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Cardiac T1 mapping is a valuable quantitative MRI technique for diagnosing diffuse myocardial diseases. Traditional methods, relying on breath-hold sequences and cardiac triggering based on an ECG signal, face challenges with patient…
Coronary anatomy governs local haemodynamics associated with atherosclerotic development, progression and ultimately adverse clinical outcomes. However, lack of large sample size studies and methods to link adverse haemodynamics to…
Early afterdepolarizations (EADs) are pathological voltage oscillations in cardiomyocytes that have been observed in response to a number of pharmacological agents and disease conditions. EADs are small voltage fluctuations that occur…
We propose and analyse the properties of a new class of models for the electromechanics of cardiac tissue. The set of governing equations consists of nonlinear elasticity using a viscoelastic and orthotropic exponential constitutive law…
Falling in Parkinsonian syndromes (PS) is associated with postural instability and consists a common cause of disability among PS patients. Current posturographic practices record the body's center-of-pressure displacement (statokinesigram)…
We present the multiscale entropy analysis of short term physiological time series of simultaneously acquired samples of heart rate, blood pressure and lung volume, from healthy subjects and from subjects with Chronic Heart Failure.…
Focused transmits are the most commonly used transmit strategy for echocardiograms, but suffer from relatively low frame rates, and in 3D, even lower volume rates. Fast imaging based on unfocused transmits has disadvantages such as motion…
We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…
Subject-specific modeling is a powerful tool in cardiovascular research, providing insights beyond the reach of current clinical diagnostics. Limitations in available clinical data require the incorporation of uncertainty into models to…
The purpose of the present study was to determine the effects of a plantar pressure-based, tongue-placed tactile biofeedback on postural control mechanisms during quiet standing. To this aim, sixteen young healthy adults were asked to stand…
Arrhythmia is an abnormality of the heart's rhythm, caused by problems in the conductive system and resulting in irregular heartbeats. There is increasing evidence that undertaking frequent endurance sports training elevates one's risk of…
Discrete-time fractional-order dynamical systems (DT-FODS) have found innumerable applications in the context of modeling spatiotemporal behaviors associated with long-term memory. Applications include neurophysiological signals such as…
The sit-to-stand movement is a key feature for wide adoption of powered lower limb orthoses for patients with complete paraplegia. In this paper we study the control of the ascending phase of the sit-to-stand movement for a minimally…
Atrial fibrillation is a clinical arrhythmia with multifactorial mechanisms still unresolved. Time-frequency analysis of epicardial electrograms has been investigated to study atrial fibrillation. However, deeper understanding of atrial…
Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…
The response to the field sequence of nonresonant hole burning, a pump-wait-probe experiment originally designed to investigate slow relaxation in complex systems, is calculated for a model of Brownian oscillators, thus including inertial…
We present a conditional space-time proper orthogonal decomposition (POD) formulation that is tailored to the eduction of the average, rare or intermittent event from an ensemble of realizations of a fluid process. By construction, the…
Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…
In living organisms, the natural motion caused by the heartbeat, breathing, or muscle movements leads to the deformation of tissue caused by translation and stretching of the tissue structure. This effect results in the displacement or…
The asteroseismology of rapidly rotating pulsating stars is hindered by our poor knowledge of the effect of the rotation on the oscillation properties. Here we present an asymptotic analysis of high-frequency acoustic modes in rapidly…