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Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing the multiple biomechanical parameters of arteries simultaneously at different time…

Human joint dynamic stiffness plays an important role in the stability of performance augmentation exoskeletons. In this paper, we consider a new frequency domain model of the human joint dynamics which features a complex value stiffness.…

Robotics · Computer Science 2020-05-04 Binghan He , Huang Huang , Gray C. Thomas , Luis Sentis

Airflow signal encodes rich information about respiratory system. While the gold standard for measuring airflow is to use a spirometer with an occlusive seal, this is not practical for ambulatory monitoring of patients. Advances in sensor…

Machine Learning · Statistics 2020-08-12 Whitney K. Huang , Yu-Min Chung , Yu-Bo Wang , Jeff E. Mandel , Hau-Tieng Wu

Cardiovascular diseases (CVDs) represent significant global health challenges today, necessitating regular and reliable monitoring to enable early intervention. Phonocardiogram (PCG) signals present a promising non-invasive method for…

Signal Processing · Electrical Eng. & Systems 2026-05-25 Abdul Ahad Mamun , Utsab Saha , Md Hasibul Hasan , Shahed Ahmed , MD Jahin Alam

The mechanisms underlying cardiac fibrillation have been investigated for over a century, but we are still finding surprising results that change our view of this phenomenon. The present study focuses on the transition from normal rhythm to…

Tissues and Organs · Quantitative Biology 2024-11-15 Alejandro Garzón , Roman O. Grigoriev

The electrocardiogram (ECG) is modulated by torso-heart anatomy, and this challenges patients' diagnosis and risk stratification. This study aims to quantify how torso-heart anatomical factors affect sex-differences in ECG biomarkers in…

Background: Several studies have shown that both respiratory and cardiac motion can be extracted from the Pilot Tone (PT) signal successfully. However, most of these studies were performed in healthy volunteers. In addition, validating PT…

Signal Processing · Electrical Eng. & Systems 2024-02-29 Chong Chen , Yingmin Liu , Orlando P. Simonetti , Matthew Tong , Ning Jin , Mario Bacher , Peter Speier , Rizwan Ahmad

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for…

Signal Processing · Electrical Eng. & Systems 2025-12-02 Yiqiao Chen , Fazheng Xu , Zijian Huang , Juchi He , Zhenghui Feng

Autonomic Dysreflexia (AD) is a potentially life-threatening condition characterized by sudden, severe blood pressure (BP) spikes in individuals with spinal cord injury (SCI). Early, accurate detection is essential to prevent cardiovascular…

Signal Processing · Electrical Eng. & Systems 2026-03-18 Bertram Fuchs , Mehdi Ejtehadi , Ana Cisnal , Jürgen Pannek , Anke Scheel-Sailer , Robert Riener , Inge Eriks-Hoogland , Diego Paez-Granados

We study the phase-synchronization properties of systolic and diastolic arterial pressure in healthy subjects. We find that delays in the oscillatory components of the time series depend on the frequency bands that are considered, in…

The sinoatrial-node (SAN) is a complex heterogeneous tissue that generates a stable rhythm in healthy hearts, yet a general mechanistic explanation for when and how this tissue remains stable is lacking. Although computational and…

Cell Behavior · Quantitative Biology 2018-09-14 Cheng Ly , Seth H. Weinberg

Objective: Syncope is a sudden loss of consciousness with loss of postural tone and spontaneous recovery; it is a common condition, albeit one that is challenging to accurately diagnose. Uncertainties about the triggering mechanisms and…

Quantitative Methods · Quantitative Biology 2016-09-08 Joseph Hart , Jesper Mehlsen , Christian H. Olsen , Mette Sofie Olufsen , Pierre Gremaud

Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting over 1% of the population. It is usually triggered by irregular electrical impulses that cause the atria to contract irregularly and…

The understanding of complex physical or biological systems nearly always requires a characterisation of the variability that underpins these processes. In addition, the data used to calibrate such models may also often exhibit considerable…

Tissues and Organs · Quantitative Biology 2017-06-22 Brodie A. J. Lawson , Christopher C. Drovandi , Nicole Cusimano , Pamela Burrage , Blanca Rodriguez , Kevin Burrage

Stability of bipedal systems in frontal plane is affected by the hip offset, to the extent that adjusting stride time using feedforward retraction and extension of the legs can lead to stable oscillations without feedback control. This…

Robotics · Computer Science 2025-10-28 Harsha Karunanayaka , Siavash Rezazadeh

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

Tissues and Organs · Quantitative Biology 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Delay differential equations (DDEs) are widely used in mathematical modeling to describe physical and biological systems. Delays can impact model dynamics, resulting in oscillatory behavior. In physiological systems, this instability may…

Dynamical Systems · Mathematics 2019-12-05 E. Benjamin Randall , Nicholas Z. Randolph , Mette S. Olufsen

Atrial fibrillation is a heart rhythm disorder that affects tens of millions people worldwide. The most effective treatment is catheter ablation. This involves irreversible heating of abnormal cardiac tissue facilitated by electroanatomical…

Medical Physics · Physics 2022-11-01 Jiyue He , Arkady Pertsov , Sanjay Dixit , Katie Walsh , Eric Toolan , Rahul Mangharam

Cuffless blood pressure (BP) estimation based on Pulse Transit Time (PTT) has emerged as a promising solution for continuous health monitoring. However, conventional models relying on the Moens-Korteweg equation often fail during rapid…

Human-Computer Interaction · Computer Science 2026-05-01 Boyuan Gu , Yijin Yang , Shuaiqi Cheng , Xiaorong Ding

Posturography is routinely used to qualitatively assess one of the cardinal symptoms of Parkinson's disease -- postural instability. While most measures of balance control are derived from displacement of the center of pressure there is…

Neurons and Cognition · Quantitative Biology 2017-10-24 Miroslaw Latka , Slawomir Budrewicz , Klaudia Kozlowska , Magdalena Koszewicz , Bruce J. West
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