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Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

This study presents a novel state estimation approach integrating Deep Neural Networks (DNNs) into Moving Horizon Estimation (MHE). This is a shift from using traditional physics-based models within MHE towards data-driven techniques.…

Systems and Control · Electrical Eng. & Systems 2025-07-29 Alexander Winkler , Pranav Shah , Katrin Baumgärtner , Vasu Sharma , David Gordon , Jakob Andert

This paper introduces an algorithm for the detection of change-points and the identification of the corresponding subsequences in transient multivariate time-series data (MTSD). The analysis of such data has become more and more important…

Signal Processing · Electrical Eng. & Systems 2023-04-05 Jonas Köhne , Lars Henning , Clemens Gühmann

Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and…

Machine Learning · Computer Science 2025-07-18 Weijieying Ren , Jingxi Zhu , Zehao Liu , Tianxiang Zhao , Vasant Honavar

In recent years, deep learning methods have achieved great success in various fields due to their strong performance in practical applications. In this paper, we present a light-weight neural network for Parkinson's disease diagnostics, in…

Over the last two decades, the Latent Position Model (LPM) has become a prominent tool to obtain model-based visualizations of networks. However, the geometric structure of the LPM is inherently symmetric, in the sense that outgoing and…

Methodology · Statistics 2026-02-02 Chaoyi Lu , Riccardo Rastelli

Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables are useful in predicting clinical outcomes can be…

Machine Learning · Statistics 2019-04-03 Eugene Laksana , Melissa Aczon , Long Ho , Cameron Carlin , David Ledbetter , Randall Wetzel

Despite the growing interest in continual learning, most of its contemporary works have been studied in a rather restricted setting where tasks are clearly distinguishable, and task boundaries are known during training. However, if our goal…

Machine Learning · Computer Science 2020-01-16 Soochan Lee , Junsoo Ha , Dongsu Zhang , Gunhee Kim

Early detection of Alzheimer disease is crucial for deploying interventions and slowing the disease progression. A lot of machine learning and deep learning algorithms have been explored in the past decade with the aim of building an…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Narotam Singh , Patteshwari. D , Neha Soni , Amita Kapoor

Event-based models (EBMs) infer disease progression from cross-sectional data, and standard EBMs assume a single underlying disease per individual. In contrast, mixed pathologies are common in neurodegeneration. We introduce the Joint…

Machine Learning · Computer Science 2026-01-14 Hongtao Hao , Joseph L. Austerweil

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

Machine Learning · Computer Science 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

In today's interconnected digital landscape, the proliferation of malware poses a significant threat to the security and stability of computer networks and systems worldwide. As the complexity of malicious tactics, techniques, and…

Cryptography and Security · Computer Science 2023-05-26 Dhruv Nandakumar , Devin Quinn , Elijah Soba , Eunyoung Kim , Christopher Redino , Chris Chan , Kevin Choi , Abdul Rahman , Edward Bowen

Obesity is a major health problem, increasing the risk of various major chronic diseases, such as diabetes, cancer, and stroke. While the role of obesity identified by cross-sectional BMI recordings has been heavily studied, the role of BMI…

Machine Learning · Computer Science 2024-12-03 Md Mozaharul Mottalib , Jessica C Jones-Smith , Bethany Sheridan , Rahmatollah Beheshti

Deep Learning (DL) requires a large amount of training data to provide quality outcomes. However, the field of medical imaging suffers from the lack of sufficient data for properly training DL models because medical images require manual…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Laith Alzubaidi , J. Santamaría , Mohamed Manoufali , Beadaa Mohammed , Mohammed A. Fadhel , Jinglan Zhang , Ali H. Al-Timemy , Omran Al-Shamma , Ye Duan

Electronic Health Records (EHR) contain valuable clinical information for predicting patient outcomes and guiding healthcare decisions. However, effectively modeling Electronic Health Records (EHRs) requires addressing data heterogeneity…

Machine Learning · Computer Science 2025-07-22 Junhan Yu , Zhunyi Feng , Junwei Lu , Tianxi Cai , Doudou Zhou

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

The ability to accurately forecast and control inpatient census, and thereby workloads, is a critical and longstanding problem in hospital management. Majority of current literature focuses on optimal scheduling of inpatients, but largely…

Methodology · Statistics 2017-01-31 Chitta Ranjan , Kamran Paynabar , Jonathan E. Helm , Julian Pan

Deep Learning (DL) has shown great promise in the unsupervised task of clustering. That said, while in classical (i.e., non-deep) clustering the benefits of the nonparametric approach are well known, most deep-clustering methods are…

Machine Learning · Computer Science 2022-03-29 Meitar Ronen , Shahaf E. Finder , Oren Freifeld

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Background: Topological data analysis (TDA) has exploded as a tool for analyzing and making sense of high dimensional datasets across a variety of fields. Mapper is a tool from TDA that captures low-dimensional structure from…

General Topology · Mathematics 2025-12-04 Brittany Story , Zhibin Zhou , Ramesh Srinivasan , Scott Kerick , David Boothe , Piotr J. Franaszczuk