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Understanding the mechanisms underlying general anesthesia would be a key step towards understanding consciousness. The process of xenon-induced general anesthesia has been shown to involve electron transfer, and the potency of xenon as a…

Biological Physics · Physics 2021-03-22 Jordan Smith , Hadi Zadeh Haghighi , Dennis Salahub , Christoph Simon

Weak magnetic fields and isotopes have been shown to influence biological processes; however, the underlying mechanisms remain poorly understood, particularly because the corresponding interaction energies are far below thermal energies,…

The N-methyl-D-aspartate receptor is a prominent player in brain development and functioning. Perturbations to its functioning through external stimuli like magnetic fields can potentially affect the brain in numerous ways. Various studies…

Biological Physics · Physics 2023-10-27 Parvathy S Nair , Hadi Zadeh-Haghighi , Christoph Simon

Drosophila's circadian clock can be perturbed by magnetic fields, as well as by lithium administration. Cryptochromes are critical for the circadian clock. Further, the radical pairs in cryptochrome also can explain magnetoreception in…

Biological Physics · Physics 2021-07-23 Hadi Zadeh-Haghighi , Christoph Simon

One possible explanation for magnetosensing in biology, such as avian magnetoreception, is based on the spin dynamics of certain chemical reactions that involve radical pairs. Radical pairs have been suggested to also play a role in…

Biological Physics · Physics 2023-01-23 Hadi Zadeh-Haghighi , Christoph Simon

A large and growing body of research shows that weak magnetic fields can significantly influence various biological systems, including plants, animals, and humans. However, the underlying mechanisms behind these phenomena remain elusive. It…

Biological Physics · Physics 2022-04-21 Hadi Zadeh-Haghighi , Christoph Simon

The radical pair mechanism is a leading hypothesis in animal magnetic navigation. This mechanism associates the magnetic sense with the visual system, the radical pairs in cryptochromes of the eye retina being specialized magnetic receptors…

Biological Physics · Physics 2018-02-09 Vladimir N. Binhi , Frank S. Prato

My findings show what causes loss of awareness, anesthesia, memory replay, opioid induced respiratory depression (OIRD), and slow-wave sleep (SWS). Opiates are fast pain relievers and anesthetics that can cause respiratory arrest. I found…

Neurons and Cognition · Quantitative Biology 2025-12-12 Karin Vadovičová

Adult hippocampal neurogenesis and hippocampus-dependent cognition in mice have been found to be adversely affected by hypomagnetic field exposure. The effect concurred with a reduction of reactive oxygen species in the absence of the…

Biological Physics · Physics 2022-10-12 Jess Ramsay , Daniel R. Kattnig

Weak magnetic field exposure can affect many biological processes across a wide range of living organisms. Recently, it has been observed that weak magnetic fields can modulate reactive oxygen species (ROS) concentration, affecting…

Biological Physics · Physics 2023-12-12 Rishabh , Hadi Zadeh-Haghighi , Christoph Simon

It is known that bipolar disorder and its lithium treatment involve the modulation of oxidative stress. Moreover, it has been observed that lithium's effects are isotope-dependent. Based on these findings, here we propose that lithium…

Biological Physics · Physics 2021-03-23 Hadi Zadeh-Haghighi , Christoph Simon

Exposures to a hypomagnetic field can affect biological processes. Recently, it has been observed that hypomagnetic field exposure can adversely affect adult hippocampal neurogenesis and hippocampus-dependent cognition in mice. In the same…

Neurons and Cognition · Quantitative Biology 2021-10-26 Rishabh , Hadi Zadeh-Haghighi , Dennis Salahub , Christoph Simon

Planarian is an intriguing model system wherein the effect of electric and magnetic fields can be studied on various biochemical pathways during cell morphogenesis. Recent experimental observations have demonstrated the non-trivial…

Biological Physics · Physics 2024-03-04 Yash Tiwari , Parul Raghuvanshi , Vishvendra Singh Poonia

A general mechanism for anesthetic function is not fully understood. Similarly, the mechanism by which xenon, a chemically inert noble gas, can produce anesthetic effects remains ambiguous. However, a previous study reported a surprisingly…

Biological Physics · Physics 2026-05-20 Allan Wang , S. Furkan Ozturk

The mechanism used by migratory birds to orientate themselves using the geomagnetic field is still a mystery in many species. The radical pair mechanism, in which very weak magnetic fields can influence certain types of spin-dependent…

Biological Physics · Physics 2013-09-24 Neill Lambert , Simone De Liberato , Clive Emary , Franco Nori

The yield of chemical reactions involving intermediate radical pairs is influenced by magnetic fields well beyond the levels expected from energy considerations. This dependence can be traced back to the microscopic dynamics of electron…

Biological Physics · Physics 2013-05-29 Gian Giacomo Guerreschi , Markus Tiersch , Ulrich E. Steiner , Hans J. Briegel

The Radical Pair Mechanism is a canonical model for the magnetosensitivity of chemical reaction processes. The key ingredient of this model is the hyperfine interaction that induces a coherent mixing of singlet and triplet electron spin…

Chemical Physics · Physics 2018-09-12 Robert H. Keens , Salil Bedkihal , Daniel R. Kattnig

In order to investigate whether the radical pair mechanism (RPM) can explain the effects of telecommunication frequency radiation on reactive oxygen species production, we modelled the effects of oscillating magnetic fields on radical pair…

Biological Physics · Physics 2024-07-08 Owaiss Talbi , Hadi Zadeh-Haghighi , Christoph Simon

Magnetic field effects (MFE) in certain chemical reactions have been well established in the last five decades and are attributed to the evolution of transient radical-pairs whose spin dynamics are determined by local and external magnetic…

A leading theory for the biological effects of low-intensity magnetic fields is the spin-chemical Radical Pair Mechanism. This mechanism is best described by the master equation for the density matrix of an open quantum system, which…

Biological Physics · Physics 2025-04-10 Vladimir N. Binhi
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