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Federated Learning (FL) facilitates collaborative model training across decentralized clients while preserving data privacy by avoiding raw data exchange. Despite its potential, FL performance is often compromised by data heterogeneity…

Machine Learning · Computer Science 2026-05-12 Qijun Hou , Yuchen Shi , Pingyi Fan , Khaled B. Letaief

Federated learning (FL) is an emerging paradigm that permits a large number of clients with heterogeneous data to coordinate learning of a unified global model without the need to share data amongst each other. A major challenge in…

Machine Learning · Computer Science 2023-11-16 Irene Tenison , Sai Aravind Sreeramadas , Vaikkunth Mugunthan , Edouard Oyallon , Irina Rish , Eugene Belilovsky

Federated learning (FL) allows multiple clients to collaboratively learn a globally shared model through cycles of model aggregation and local model training, without the need to share data. Most existing FL methods train local models…

Machine Learning · Computer Science 2023-12-05 Liangxi Liu , Xi Jiang , Feng Zheng , Hong Chen , Guo-Jun Qi , Heng Huang , Ling Shao

In this paper, we question the rationale behind propagating large numbers of parameters through a distributed system during federated learning. We start by examining the rank characteristics of the subspace spanned by gradients across…

Machine Learning · Computer Science 2022-02-02 Sheikh Shams Azam , Seyyedali Hosseinalipour , Qiang Qiu , Christopher Brinton

Machine learning methods for estimating heterogeneous treatment effects (HTE) facilitate large-scale personalized decision-making across various domains such as healthcare, policy making, education, and more. Current machine learning…

Machine Learning · Computer Science 2024-06-25 Disha Makhija , Joydeep Ghosh , Yejin Kim

Machine learning has become integral to medical research and is increasingly applied in clinical settings to support diagnosis and decision-making; however, its effectiveness depends on access to large, diverse datasets, which are limited…

Machine Learning · Computer Science 2026-04-21 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

The federated learning paradigm is wellsuited for the field of medical image analysis, as it can effectively cope with machine learning on isolated multicenter data while protecting the privacy of participating parties. However, current…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Zhekai Zhou , Guibo Luo , Mingzhi Chen , Zhenyu Weng , Yuesheng Zhu

We propose a method for inference in generalised linear mixed models (GLMMs) and several extensions of these models. First, we extend the GLMM by allowing the distribution of the random components to be non-Gaussian, that is, assuming an…

Methodology · Statistics 2021-07-27 Jeanett S. Pelck , Rodrigo Labouriau

Federated learning has attracted significant attention as a privacy-preserving framework for training personalised models on multi-source heterogeneous data. However, most existing approaches are unable to handle scenarios where subgroup…

Methodology · Statistics 2025-10-14 Changxin Yang , Zhongyi Zhu , Heng Lian

This study analyzes the performance of domain-specific Large Language Models (LLMs) for the medical field by integrating Retrieval-Augmented Generation (RAG) systems within a federated learning framework. Leveraging the inherent advantages…

Computation and Language · Computer Science 2025-01-09 Jincheol Jung , Hongju Jeong , Eui-Nam Huh

Generalized linear mixed models (GLMMs) are often used for analyzing correlated non-Gaussian data. The likelihood function in a GLMM is available only as a high dimensional integral, and thus closed-form inference and prediction are not…

Methodology · Statistics 2022-06-27 Vivekananda Roy

This paper presents a novel approach to classical linear regression, enabling model computation from data streams or in a distributed setting while preserving data privacy in federated environments. We extend this framework to generalized…

Computation · Statistics 2026-05-29 Daniel Tinoco , Raquel Menezes , Carlos Baquero

Federated learning allows edge devices to collaboratively learn a shared model while keeping the training data on device, decoupling the ability to do model training from the need to store the data in the cloud. We propose Federated matched…

Machine Learning · Computer Science 2020-02-18 Hongyi Wang , Mikhail Yurochkin , Yuekai Sun , Dimitris Papailiopoulos , Yasaman Khazaeni

In recent years, a comprehensive study of multi-view datasets (e.g., multi-omics and imaging scans) has been a focus and forefront in biomedical research. State-of-the-art biomedical technologies are enabling us to collect multi-view…

Machine Learning · Statistics 2020-04-30 Md Ashad Alam , Chuan Qiu , Hui Shen , Yu-Ping Wang , Hong-Wen Deng

This paper investigates Gaussian copula mixture models (GCMM), which are an extension of Gaussian mixture models (GMM) that incorporate copula concepts. The paper presents the mathematical definition of GCMM and explores the properties of…

Machine Learning · Computer Science 2023-05-25 Ke Wan , Alain Kornhauser

Federated learning enables distributed clients to collaborate on training while storing their data locally to protect client privacy. However, due to the heterogeneity of data, models, and devices, the final global model may need to perform…

Machine Learning · Computer Science 2024-06-25 Wolong Xing , Zhenkui Shi , Hongyan Peng , Xiantao Hu , Xianxian Li

Inference for spatial generalized linear mixed models (SGLMMs) for high-dimensional non-Gaussian spatial data is computationally intensive. The computational challenge is due to the high-dimensional random effects and because Markov chain…

Computation · Statistics 2018-10-09 Yawen Guan , Murali Haran

Generalized linear mixed models (GLMMs) are widely used in research for their ability to model correlated outcomes with non-Gaussian conditional distributions. The proper selection of fixed and random effects is a critical part of the…

Computation · Statistics 2024-04-18 Hillary M. Heiling , Naim U. Rashid , Quefeng Li , Joseph G. Ibrahim

Federated learning is becoming an increasingly viable and accepted strategy for building machine learning models in critical privacy-preserving scenarios such as clinical settings. Often, the data involved is not limited to clinical data…

Machine Learning · Statistics 2024-07-25 Celeste Damiani , Yulia Rodina , Sergio Decherchi

Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, fitting mvLMMs is computationally non-trivial,…

Quantitative Methods · Quantitative Biology 2013-09-13 Xiang Zhou , Matthew Stephens