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Modeling and simulation are recognized as important aspects of the scientific method for more than 70 years but its adoption in biology has been slow. Debates on its representativeness, usefulness, and whether the effort spent on such…

Quantitative Methods · Quantitative Biology 2023-02-21 Maurice HT Ling

Hardware, systems and algorithms research communities have historically had different incentive structures and fluctuating motivation to engage with each other explicitly. This historical treatment is odd given that hardware and software…

Computers and Society · Computer Science 2020-09-23 Sara Hooker

Evidence-based medicine promises to improve the quality of healthcare by empowering medical decisions and practices with the best available evidence. The rapid growth of medical evidence, which can be obtained from various sources, poses a…

Artificial Intelligence is providing astonishing results, with medicine being one of its favourite playgrounds. In a few decades, computers may be capable of formulating diagnoses and choosing the correct treatment, while robots may perform…

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

The current literature on AI-advised decision making -- involving explainable AI systems advising human decision makers -- presents a series of inconclusive and confounding results. To synthesize these findings, we propose a simple theory…

Artificial Intelligence · Computer Science 2024-02-05 Raymond Fok , Daniel S. Weld

The robust development of Electronic Health Records (EHRs) causes a significant growth in sharing EHRs for clinical research. However, such a sharing makes it difficult to protect patient's privacy. A number of automated de-identification…

Cryptography and Security · Computer Science 2012-11-19 Jie Qian , Nafees Qamar

The rapid evolution of artificial intelligence has led to expectations of transformative impact on science, yet current systems remain fundamentally limited in enabling genuine scientific discovery. This perspective contends that progress…

Artificial Intelligence · Computer Science 2025-12-16 Karthik Duraisamy

There is a widespread perception that pharmaceutical R&D is facing a productivity crisis characterised by stagnation in the numbers of new drug approvals in the face of increasing R&D costs. This study explores pharmaceutical R&D dynamics…

Data-mining techniques have frequently been developed for Spontaneous reporting databases. These techniques aim to find adverse drug events accurately and efficiently. Spontaneous reporting databases are prone to missing information, under…

Computational Engineering, Finance, and Science · Computer Science 2013-07-04 Jenna Reps , Jan Feyereisl , Jonathan M. Garibaldi , Uwe Aickelin , Jack E. Gibson , Richard B. Hubbard

Abstruse learning algorithms and complex datasets increasingly characterize modern clinical decision support systems (CDSS). As a result, clinicians cannot easily or rapidly scrutinize the CDSS recommendation when facing a difficult…

Artificial Intelligence · Computer Science 2021-11-02 Bojian Hou , Hao Zhang , Gur Ladizhinsky , Gur Ladizhinsky , Stephen Yang , Volodymyr Kuleshov , Fei Wang , Qian Yang

The focus of this paper is on wearable technologies which are increasingly being employed in the medical field. From smart watches to smart glasses, from electronic textile to data gloves; several gadgets are playing important roles in…

Computers and Society · Computer Science 2017-04-21 Erkan Bostanci

Park et al. [1] reported a decline in the disruptiveness of scientific and technological knowledge over time. Their main finding is based on the computation of CD indices, a measure of disruption in citation networks [2], across almost 45…

Digital Libraries · Computer Science 2024-02-23 Vincent Holst , Andres Algaba , Floriano Tori , Sylvia Wenmackers , Vincent Ginis

Machine learning promises to revolutionize clinical decision making and diagnosis. In medical diagnosis a doctor aims to explain a patient's symptoms by determining the diseases \emph{causing} them. However, existing diagnostic algorithms…

Machine Learning · Statistics 2020-03-17 Jonathan G. Richens , Ciaran M. Lee , Saurabh Johri

eHealth has expanded hugely over the last fifteen years and continues to evolve, providing greater benefits for patients, health care professionals and providers alike. The technologies that support these systems have become increasingly…

Computers and Society · Computer Science 2013-02-25 Alice Good , Arunasalam Sambhanthan

Missing values are a fundamental problem in data science. Many datasets have missing values that must be properly handled because the way missing values are treated can have large impact on the resulting machine learning model. In medical…

Machine Learning · Computer Science 2023-04-25 Zhi Chen , Sarah Tan , Urszula Chajewska , Cynthia Rudin , Rich Caruana

In recent years, machine learning (ML) has become a key enabling technology for the sciences and industry. Especially through improvements in methodology, the availability of large databases and increased computational power, today's ML…

Artificial Intelligence · Computer Science 2019-09-27 Wojciech Samek , Klaus-Robert Müller

Forensic science is usually taken to mean the application of a broad spectrum of scientific tools to answer questions of interest to the legal system. Despite such popular television series as CSI: Crime Scene Investigation and its…

Applications · Statistics 2009-09-29 Stephen E. Fienberg

As AI hype continues to grow, organizations face pressure to broadcast or downplay purported AI initiatives - even when contrary to truth. This paper introduces AI-washing as overstating (deceptive boasting) or understating (deceptive…

Computers and Society · Computer Science 2025-07-08 Greg Nyilasy , Harsha Gangadharbatla

People who are blind employ unique strategies when performing instrumental activities of daily living (iADLs), often relying on multiple sensory modalities and assistive technologies. While prior research has extensively explored adaptive…

Human-Computer Interaction · Computer Science 2025-02-25 Lily M. Turkstra , Tanya Bhatia , Alexa Van Os , Michael Beyeler