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Metastability, characterized by a variability of regimes in time, is a ubiquitous type of neural dynamics. It has been formulated in many different ways in the neuroscience literature, however, which may cause some confusion. In this…

Neurons and Cognition · Quantitative Biology 2024-05-24 Kalel L. Rossi , Roberto C. Budzinski , Everton S. Medeiros , Bruno R. R. Boaretto , Lyle Muller , Ulrike Feudel

Biological membranes are able to exhibit various morphology due to the fluidity of the lipid molecules within the monolayers. The shape transformation of membranes has been well described by the classical Helfrich theory, which consists…

Soft Condensed Matter · Physics 2023-02-24 Mei-Ting Wang , Rui Ma , Chen-Xu Wu

We study data-driven learning of robust stochastic control for infinite-horizon systems with potentially continuous state and action spaces. In many managerial settings--supply chains, finance, manufacturing, services, and dynamic…

Machine Learning · Statistics 2025-11-18 Shengbo Wang , Jason Meng , Nian Si , Jose Blanchet , Zhengyuan Zhou

Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…

Soft Condensed Matter · Physics 2025-09-04 James Clarke , Jake McGrath , Colin Johnson , José Alvarado

One of the most important branches of nonlinear control theory is the so-called sliding-mode. Its aim is the design of a (nonlinear) feedback law that brings and maintains the state trajectory of a dynamic system on a given sliding surface.…

Systems and Control · Electrical Eng. & Systems 2021-09-14 Mauro Bisiacco , Gianluigi Pillonetto

Bone remodeling involves the coordinated removal of bone by osteoclasts and addition of bone by osteoblasts, a process that is modulated by the prevailing mechanical environment. In this paper a fully coupled model of bone remodeling is…

Tissues and Organs · Quantitative Biology 2012-08-02 Stefan Scheiner , Peter Pivonka , Christian Hellmich , David W. Smith

Control of a dynamical system without the knowledge of dynamics is an important and challenging task. Modern machine learning approaches, such as deep neural networks (DNNs), allow for the estimation of a dynamics model from control inputs…

Systems and Control · Electrical Eng. & Systems 2023-11-14 Suruchi Sharma , Volodymyr Makarenko , Gautam Kumar , Stas Tiomkin

Chaos control techniques have been applied to a wide variety of experimental systems, including magneto-elastic ribbons, lasers, chemical reactions, arrhythmic cardiac tissue, and spontaneously bursting neuronal networks. An underlying…

chao-dyn · Physics 2008-02-03 David J. Christini , James J. Collins

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Soft Condensed Matter · Physics 2025-11-13 Nivedina A. Sarma , David A. King , Xuefei Wu , Brett A. Helms , Paul D. Ashby , Thomas P. Russell , Ahmad K. Omar

This paper addresses the problem of controlling the temporal dynamics of complex nonlinear network-coupled dynamical systems, specifically in terms of neurodynamics. Based on the Lyapunov direct method, we derive a control strategy with…

Systems and Control · Electrical Eng. & Systems 2024-05-14 Zhongye Xia , Weibin Li , Zhichao Liang , Kexin Lou , Quanying Liu

This paper studies set-invariance and stabilization of hyperbolic sets over rate-limited channels for discrete-time control systems. We first investigate structural and control-theoretic properties of hyperbolic sets, in particular such…

Optimization and Control · Mathematics 2021-05-20 Christoph Kawan

Safety and stability are common requirements for robotic control systems; however, designing safe, stable controllers remains difficult for nonlinear and uncertain models. We develop a model-based learning approach to synthesize robust…

Systems and Control · Electrical Eng. & Systems 2021-10-08 Charles Dawson , Zengyi Qin , Sicun Gao , Chuchu Fan

Some biological systems operate at the critical point between stability and instability and this requires a fine-tuning of parameters. We bring together two examples from the literature that illustrate this: neural integration in the…

Optimization and Control · Mathematics 2007-05-23 Luc Moreau , Eduardo Sontag

Membranes are ubiquitous in nature with primary functions that include adaptive filtering and selective transport of chemical and molecular species. Being critical to cellular functions, they are also fundamental in many areas of science…

Bang-bang control is ubiquitous for Optimal Control Problems (OCPs) where the constrained control variable appears linearly in the dynamics and cost function. Based on the Pontryagin's Minimum Principle, the indirect method is widely used…

Optimization and Control · Mathematics 2023-12-04 Kun Wang , Zheng Chen , Zhenyu Wei , Fangmin Lu , Jun Li

Robust control theory has been successfully applied to numerous real-world problems using a small set of devices called {\it controllers}. However, the real systems represented by networks contain unreliable components and modern robust…

Physics and Society · Physics 2015-06-23 Jose C. Nacher , Tatsuya Akutsu

Controller design faces a trade-off between robustness and performance, and the reliability of linear controllers has caused many practitioners to focus on the former. However, there is renewed interest in improving system performance to…

Optimization and Control · Mathematics 2012-08-07 Anil Aswani , Humberto Gonzalez , S. Shankar Sastry , Claire Tomlin

Stochastic thermodynamics provides a useful set of tools to analyze and constrain the behavior of far from equilibrium systems. In this paper, we report an application of ideas from stochastic thermodynamics to the problem of membrane…

Soft Condensed Matter · Physics 2019-10-25 Michael Nguyen , Suriyanarayanan Vaikuntanathan

The bang-bang optimal control method was proposed for glow discharge plasma actuators, taking account of practical issues, such as limited actuation states with instantaneously varied aerodynamic control performance. Hence, the main…

Plasma Physics · Physics 2012-04-12 Qingkai Wei , Zhongguo Niu , Bao Chen , Xun Huang

We study optimal control problems for interacting branching diffusion processes, a class of measure-valued dynamics capturing both spatial motion and branching mechanisms. From the perspective of the dynamic programming principle, we…

Optimization and Control · Mathematics 2026-01-19 Antonio Ocello