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Model explainability is crucial for human users to be able to interpret how a proposed classifier assigns labels to data based on its feature values. We study generalized linear models constructed using sets of feature value rules, which…

Machine Learning · Statistics 2023-11-06 Sanjeeb Dash , Soumyadip Ghosh , Joao Goncalves , Mark S. Squillante

Medical AI, including clinical language models, vision-language models, and multimodal health record models, already summarizes notes, answers questions, and supports decisions. Their adaptation to new populations, specialties, or care…

Artificial Intelligence · Computer Science 2025-12-01 Michelle M. Li , Ben Y. Reis , Adam Rodman , Tianxi Cai , Noa Dagan , Ran D. Balicer , Joseph Loscalzo , Isaac S. Kohane , Marinka Zitnik

Medical professionals frequently work in a data constrained setting to provide insights across a unique demographic. A few medical observations, for instance, informs the diagnosis and treatment of a patient. This suggests a unique setting…

Computation and Language · Computer Science 2022-12-06 Pankaj Sharma , Imran Qureshi , Minh Tran

Mental health is not a fixed trait but a dynamic process shaped by the interplay between individual dispositions and situational contexts. Building on interactionist and constructionist psychological theories, we develop interpretable…

Computation and Language · Computer Science 2026-03-09 Nikita Soni , August Håkan Nilsson , Syeda Mahwish , Vasudha Varadarajan , H. Andrew Schwartz , Ryan L. Boyd

Machine learning models that offer excellent predictive performance often lack the interpretability necessary to support integrated human machine decision-making. In clinical medicine and other high-risk settings, domain experts may be…

Machine Learning · Computer Science 2021-04-19 Zach Wood-Doughty , Isabel Cachola , Mark Dredze

Demand for mental health support through AI chatbots is surging, though current systems present several limitations, like sycophancy or overvalidation, and reinforcement of maladaptive beliefs. A core obstacle to the creation of better…

Computation and Language · Computer Science 2025-12-08 José Pombal , Maya D'Eon , Nuno M. Guerreiro , Pedro Henrique Martins , António Farinhas , Ricardo Rei

The last decade has seen huge progress in the development of advanced machine learning models; however, those models are powerless unless human users can interpret them. Here we show how the mind's construction of concepts and meaning can…

Machine Learning · Statistics 2016-07-04 Nick Condry

An important factor in the practical implementation of optimization models is the acceptance by the intended users. This is influenced among other factors by the interpretability of the solution process. Decision rules that meet this…

Machine Learning · Computer Science 2024-12-03 Marc Goerigk , Michael Hartisch , Sebastian Merten

In the rapidly growing literature on explanation algorithms, it often remains unclear what precisely these algorithms are for and how they should be used. In this position paper, we argue for a novel and pragmatic perspective: Explainable…

Machine Learning · Computer Science 2025-06-17 Sebastian Bordt , Eric Raidl , Ulrike von Luxburg

Identification of disease subtypes and corresponding biomarkers can substantially improve clinical diagnosis and treatment selection. Discovering these subtypes in noisy, high dimensional biomedical data is often impossible for humans and…

Quantitative Methods · Quantitative Biology 2020-05-18 Marc-Andre Schulz , Matt Chapman-Rounds , Manisha Verma , Danilo Bzdok , Konstantinos Georgatzis

How can we find interpretable, domain-appropriate models of natural phenomena given some complex, raw data such as images? Can we use such models to derive scientific insight from the data? In this paper, we propose some methods for…

Machine Learning · Computer Science 2024-02-06 Christopher J. Soelistyo , Alan R. Lowe

This work addresses the challenge of providing consistent explanations for predictive models in the presence of model indeterminacy, which arises due to the existence of multiple (nearly) equally well-performing models for a given dataset…

Machine Learning · Computer Science 2023-06-14 Dan Ley , Leonard Tang , Matthew Nazari , Hongjin Lin , Suraj Srinivas , Himabindu Lakkaraju

Designing sustainable systems involves complex interactions between environmental resources, social impacts, and economic issues. In a constrained world, the challenge is to achieve a balanced design across those dimensions while avoiding…

Software Engineering · Computer Science 2024-11-28 Christophe Ponsard , Bérengère Nihoul , Mounir Touzani

Disorders of consciousness are a heterogeneous mixture of different diseases or injuries. Although some indicators and models have been proposed for prognostication, any single method when used alone carries a high risk of false prediction.…

Neurons and Cognition · Quantitative Biology 2018-09-10 Ming Song , Yi Yang , Jianghong He , Zhengyi Yang , Shan Yu , Qiuyou Xie , Xiaoyu Xia , Yuanyuan Dang , Qiang Zhang , Xinhuai Wu , Yue Cui , Bing Hou , Ronghao Yu , Ruxiang Xu , Tianzi Jiang

Survival analysis is a widely-used technique for analyzing time-to-event data in the presence of censoring. In recent years, numerous survival analysis methods have emerged which scale to large datasets and relax traditional assumptions…

Machine Learning · Computer Science 2023-11-06 Mert Ketenci , Shreyas Bhave , Noémie Elhadad , Adler Perotte

There has been a large number of studies in interpretable and explainable ML for cybersecurity, in particular, for intrusion detection. Many of these studies have significant amount of overlapping and repeated evaluations and analysis. At…

Cryptography and Security · Computer Science 2024-07-08 Omer Subasi , Johnathan Cree , Joseph Manzano , Elena Peterson

Superstatistics is a widely employed tool of non-equilibrium statistical physics which plays an important role in analysis of hierarchical complex dynamical systems. Yet, its "canonical" formulation in terms of a single nuisance parameter…

Statistical Finance · Quantitative Finance 2017-11-10 Petr Jizba , Jan Korbel , Hynek Lavička , Martin Prokš , Václav Svoboda , Christian Beck

The modeling of complex systems such as ecological or socio-economic systems can be very challenging. Although various modeling approaches exist, they are generally not compatible and mutually consistent, and empirical data often do not…

Physics and Society · Physics 2010-07-19 Dirk Helbing

To make sense of massive data, we often fit simplified models and then interpret the parameters; for example, we cluster the text embeddings and then interpret the mean parameters of each cluster. However, these parameters are often…

Artificial Intelligence · Computer Science 2025-01-14 Ruiqi Zhong , Heng Wang , Dan Klein , Jacob Steinhardt

Lending decisions are usually made with proprietary models that provide minimally acceptable explanations to users. In a future world without such secrecy, what decision support tools would one want to use for justified lending decisions?…

Machine Learning · Computer Science 2021-06-07 Chaofan Chen , Kangcheng Lin , Cynthia Rudin , Yaron Shaposhnik , Sijia Wang , Tong Wang