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We present a modelling framework for the dynamics of cells structured by the concentration of a micromolecule they contain. We derive general equations for the evolution of the cell population and of the extra-cellular concentration of the…

Cell Behavior · Quantitative Biology 2024-10-30 Michael Grinfeld , Nigel Mottram , Jozsef Farkas

The run-and-tumble (RT) dynamics followed by bacterial swimmers gives rise first to a ballistic motion due to their persistence, and later, through consecutive tumbles, to a diffusive process. Here we investigate how long it takes for a…

Soft Condensed Matter · Physics 2020-07-01 Andrea Villa-Torrealba , Cristóbal Chávez Raby , Pablo de Castro , Rodrigo Soto

Gliding is a means of locomotion on rigid substrates utilized by a number of bacteria includingmyxobacteria and cyanobacteria. One of the hypotheses advanced to explain this motility mechanism hinges on the role played by the slime…

Biological Physics · Physics 2015-03-02 Epifanio G. Virga

We present an \textit{ab initio} method of diffusion, relaxation and dephasing processes of arbitrary observables, and corresponding diffusion lengths and lifetimes in solids. The method is based on linearized density-matrix master…

Computational Physics · Physics 2025-09-29 Junqing Xu

Turbulence has been recognized as a factor of paramount importance for the survival or extinction of sinking phytoplankton species. However, dealing with its multiscale nature in models of coupled fluid and biological dynamics is a…

Fluid Dynamics · Physics 2021-12-10 Vinicius Beltram Tergolina , Enrico Calzavarini , Gilmar Mompean , Stefano Berti

We propose a minimal mathematical model to explain long-range coordination of dynamics of multiple cells in epithelial spreading, which may be induced, under different conditions, by a chemical signal, or mechanical stress, or both. The…

Biological Physics · Physics 2009-11-30 L. M. Pismen , S. Y. Shvartsman

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

In this paper we develop mathematical models for collective cell motility. Initially we develop a model using a linear diffusion-advection type equation and fit the parameters to data from cell motility assays. This approach is helpful in…

Cell Behavior · Quantitative Biology 2012-03-23 Jason M. Graham , Bruce P. Ayati

Understanding the impact of collective social phenomena in epidemic dynamics is a crucial task to effectively contain the disease spread. In this work we build a mathematical description for assessing the interplay between opinion…

Physics and Society · Physics 2023-03-10 Mattia Zanella

The transition from localized to systemic spreading of bacteria, viruses and other agents is a fundamental problem that spans medicine, ecology, biology and agriculture science. We have conducted experiments and simulations in a simple…

Populations and Evolution · Quantitative Biology 2009-11-10 Anna L. Lin , Bernward A. Mann , Gelsy Torres-Oviedo , Bryan Lincoln , Josef Kas , Harry L. Swinney

Myxococcus xanthus is a model organism for studying bacterial social behaviors due to its ability to form complex multi-cellular structures. Knowledge of M. xanthus surface gliding motility and the mechanisms that coordinate it are…

The complicated dynamics of the contact line of a moving droplet on a solid substrate often hamper the efficient modeling of microfluidic systems. In particular, the selection of the effective boundary conditions, specifying the contact…

This paper introduces a reaction-diffusion-chemotaxis model for bacterial aggregation patterns on the surface of thin agar plates. It is based on the non-linear degenerate cross diffusion model proposed by Kawasaki et al. (J. of Theor.…

Cell Behavior · Quantitative Biology 2013-01-23 J. Francisco Leyva , Carlos Malaga , Ramon G. Plaza

We show, in this report, how a population balance model differential equation describing batch crystal growth from solution can be solved in closed form for the case of diffusion limited growth with and without modeling the effects of…

Materials Science · Physics 2024-11-11 Douglas A. Barlow , Kylene Monaghan

We consider a system of two kinetic equations modelling a multicellular system : The first equation governs the dynamics of cells, whereas the second kinetic equation governs the dynamics of the chemoattractant. For this system, we first…

Analysis of PDEs · Mathematics 2019-07-30 Mohamed Khaladi , Nisrine Outada , Nicolas Vauchelet

The nonequilibrium process in dislocation dynamics and its relaxation to the metastable transition profile is crucial for understanding the plastic deformation caused by line defects in materials. In this paper, we consider the full…

Analysis of PDEs · Mathematics 2022-01-07 Yuan Gao , Jean-Michel Roquejoffre

Replication through cell division is one of the most fundamental processes of life and a major driver of dynamics in systems ranging from bacterial colonies to embryogenesis, tissues and tumors. While regulation often plays a role in…

Soft Condensed Matter · Physics 2024-10-21 Lukas Hupe , Yoav G. Pollack , Jonas Isensee , Aboutaleb Amiri , Ramin Golestanian , Philip Bittihn

Antibiotic-resistant bacteria has posed a grave threat to public health by causing a number of nosocomial infections in hospitals. Mathematical models have been used to study the transmission of antibiotic-resistant bacteria within a…

Populations and Evolution · Quantitative Biology 2016-10-06 Xiuli Cen , Zhilan Feng , Yiqiang Zheng , Yulin Zhao

We investigate a model, inspired by (Johnston et al., Sci. Rep., 7:42134, 2017), to describe the movement of a biological population which consists of isolated and grouped organisms. We introduce biases in the movements and then obtain a…

Analysis of PDEs · Mathematics 2023-04-06 Diego Berti , Andrea Corli , Luisa Malaguti

Diffusion of colloidal particles in a complex environment such as polymer networks or biological cells is a topic of high complexity with significant biological and medical relevance. In such situations, the interaction between the…

Statistical Mechanics · Physics 2015-11-10 Andreas M. Menzel