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Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Annual low dose computed tomography (CT) lung screening is currently advised for individuals at high risk of lung cancer (e.g., heavy smokers between 55 and 80 years old). The recommended screening practice significantly reduces all-cause…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Riqiang Gao , Lingfeng Li , Yucheng Tang , Sanja L. Antic , Alexis B. Paulson , Yuankai Huo , Kim L. Sandler , Pierre P. Massion , Bennett A. Landman

We present a method for a real time visualization and automatic processing for detection and classification of untouched cancer cells in blood during stain free imaging flow cytometry using digital holographic microscopy and machine…

Biological Physics · Physics 2021-06-15 Noga Nissim , Matan Dudaie , Itay Barnea. , Natan T. Shaked

The spread of metastases is a crucial process in which some questions remain unanswered. In this work, we focus on tumor cells circulating in the bloodstream, the so-called Circulating Tumor Cells (CTCs). Our aim is to characterize their…

Tissues and Organs · Quantitative Biology 2025-01-22 Giorgia Ciavolella , Julien Granet , Jacky Goetz , Nael Osmani , Christèle Etchegaray , Annabelle Collin

Recent advances in high-throughput electron microscopy imaging enable detailed study of centrosome aberrations in cancer cells. While the image acquisition in such pipelines is automated, manual detection of centrioles is still necessary to…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Artem Lukoyanov , Isabella Haberbosch , Constantin Pape , Alwin Kraemer , Yannick Schwab , Anna Kreshuk

Melanoma classification is a serious stage to identify the skin disease. It is considered a challenging process due to the intra-class discrepancy of melanomas, skin lesions low contrast, and the artifacts in the dermoscopy images,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Yanhui Guo , Amira S. Ashour

Cell detection in microscopy images is important to study how cells move and interact with their environment. Most recent deep learning-based methods for cell detection use convolutional neural networks (CNNs). However, inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Royden Wagner , Karl Rohr

Melanoma is the deadliest form of skin cancer. While curable with early detection, only highly trained specialists are capable of accurately recognizing the disease. As expertise is in limited supply, automated systems capable of…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Noel Codella , Quoc-Bao Nguyen , Sharath Pankanti , David Gutman , Brian Helba , Allan Halpern , John R. Smith

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li

Cervical cancer is a crucial global health concern for women, and the persistent infection of High-risk HPV mainly triggers this remains a global health challenge, with young women diagnosis rates soaring from 10\% to 40\% over three…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Tatsuhiro Baba , Abu Saleh Musa Miah , Jungpil Shin , Md. Al Mehedi Hasan

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

The ability to automatically detect certain types of cells or cellular subunits in microscopy images is of significant interest to a wide range of biomedical research and clinical practices. Cell detection methods have evolved from…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Yao Xue , Nilanjan Ray

Computational cytology is a critical, rapid-developing, yet challenging topic in the field of medical image computing which analyzes the digitized cytology image by computer-aided technologies for cancer screening. Recently, an increasing…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Hao Jiang , Yanning Zhou , Yi Lin , Ronald CK Chan , Jiang Liu , Hao Chen

Uncontrolled cell division in the brain is what gives rise to brain tumors. If the tumor size increases by more than half, there is little hope for the patient's recovery. This emphasizes the need of rapid and precise brain tumor diagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Plabon Paul , Md. Nazmul Islam , Fazle Rafsani , Pegah Khorasani , Shovito Barua Soumma

Lung cancer has been one of the most prevalent disease in recent years. According to the research of this field, more than 200,000 cases are identified each year in the US. Uncontrolled multiplication and growth of the lung cells result in…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Hesamoddin Hosseini , Reza Monsefi , Shabnam Shadroo

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-30 Zhe Zhu , Michael Harowicz , Jun Zhang , Ashirbani Saha , Lars J. Grimm , E. Shelley Hwang , Maciej A. Mazurowski

This work seeks to determine how modern machine learning techniques may be applied to the previously unexplored topic of melanoma diagnostics using digital pathology. We curated a new dataset of 50 patient cases of cutaneous melanoma using…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Adon Phillips , Iris Teo , Jochen Lang

Cluster of microcalcifications can be an early sign of breast cancer. In this paper we propose a novel approach based on convolutional neural networks for the detection and segmentation of microcalcification clusters. In this work we used…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Gabriele Valvano , Gianmarco Santini , Nicola Martini , Andrea Ripoli , Chiara Iacconi , Dante Chiappino , Daniele Della Latta