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Related papers: Multi-Modal Multi-Instance Learning for Retinal Di…

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Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Optical Coherence Tomography (OCT) is a novel and effective screening tool for ophthalmic examination. Since collecting OCT images is relatively more expensive than fundus photographs, existing methods use multi-modal learning to complement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lehan Wang , Weihang Dai , Mei Jin , Chubin Ou , Xiaomeng Li

Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li

This paper tackles automated categorization of Age-related Macular Degeneration (AMD), a common macular disease among people over 50. Previous research efforts mainly focus on AMD categorization with a single-modal input, let it be a color…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Weisen Wang , Xirong Li , Zhiyan Xu , Weihong Yu , Jianchun Zhao , Dayong Ding , Youxin Chen

In ophthalmological imaging, multiple imaging systems, such as color fundus, infrared, fluorescein angiography, optical coherence tomography (OCT) or OCT angiography, are often involved to make a diagnosis of retinal disease. Multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Aline Sindel , Bettina Hohberger , Andreas Maier , Vincent Christlein

Diabetic retinopathy (DR) is a leading cause of blindness worldwide and a common complication of diabetes. As two different imaging tools for DR grading, color fundus photography (CFP) and infrared fundus photography (IFP) are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Fan Xiao , Junlin Hou , Ruiwei Zhao , Rui Feng , Haidong Zou , Lina Lu , Yi Xu , Juzhao Zhang

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Retinal diseases can cause irreversible vision loss in both eyes if not diagnosed and treated early. Since retinal diseases are so complicated, retinal imaging is likely to show two or more abnormalities. Current deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Tariq M Khan , Shahzaib Iqbal , Syed S. Naqvi , Imran Razzak , Erik Meijering

The Vision-Language Foundation model is increasingly investigated in the fields of computer vision and natural language processing, yet its exploration in ophthalmology and broader medical applications remains limited. The challenge is the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jiawei Du , Jia Guo , Weihang Zhang , Shengzhu Yang , Hanruo Liu , Huiqi Li , Ningli Wang

The automatic diagnosis of various retinal diseases from fundus images is important to support clinical decision-making. However, developing such automatic solutions is challenging due to the requirement of a large amount of human-annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xiaomeng Li , Mengyu Jia , Md Tauhidul Islam , Lequan Yu , Lei Xing

In medical science, the use of computer science in disease detection and diagnosis is gaining popularity. Previously, the detection of disease used to take a significant amount of time and was less reliable. Machine learning (ML) techniques…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Nowshin Tasnim , Mahmudul Hasan , Ishrak Islam

We present OCTCube-M, a 3D OCT-based multi-modal foundation model for jointly analyzing OCT and en face images. OCTCube-M first developed OCTCube, a 3D foundation model pre-trained on 26,685 3D OCT volumes encompassing 1.62 million 2D OCT…

Image and Video Processing · Electrical Eng. & Systems 2024-12-20 Zixuan Liu , Hanwen Xu , Addie Woicik , Linda G. Shapiro , Marian Blazes , Yue Wu , Verena Steffen , Catherine Cukras , Cecilia S. Lee , Miao Zhang , Aaron Y. Lee , Sheng Wang

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Diabetic Retinopathy (DR), a prevalent and severe complication of diabetes, affects millions of individuals globally, underscoring the need for accurate and timely diagnosis. Recent advancements in imaging technologies, such as…

Modern foundation models provide highly expressive visual representations, yet adapting them to high-resolution medical imaging remains challenging due to limited annotations and weak supervision. Mammography, in particular, is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Nikola Jovišić , Milica Škipina , Nicola Dall'Asen , Dubravko Ćulibrk

In complex orchard environments, the phenotypic heterogeneity of different apple leaf diseases, characterized by significant variation among lesions, poses a challenge to traditional multi-scale feature fusion methods. These methods only…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Lemin Liu , Fangchao Hu , Honghua Jiang , Yaru Chen , Limin Liu , Yongliang Qiao

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Multi-modal ophthalmic image classification plays a key role in diagnosing eye diseases, as it integrates information from different sources to complement their respective performances. However, recent improvements have mainly focused on…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Ke Zou , Tian Lin , Zongbo Han , Meng Wang , Xuedong Yuan , Haoyu Chen , Changqing Zhang , Xiaojing Shen , Huazhu Fu

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy the majority of the data, while most classes have only a limited number of samples), which results in a challenging long-tailed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Lie Ju , Zhen Yu , Lin Wang , Xin Zhao , Xin Wang , Paul Bonnington , Zongyuan Ge
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