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This paper considers the problem of robustly estimating the parameters of a heavy-tailed multivariate distribution when the covariance matrix is known to have the structure of a low-rank matrix plus a diagonal matrix as considered in factor…

Computation · Statistics 2019-09-30 Rui Zhou , Junyan Liu , Sandeep Kumar , Daniel P. Palomar

Longitudinal studies of a binary outcome are common in the health, social, and behavioral sciences. In general, a feature of random effects logistic regression models for longitudinal binary data is that the marginal functional form, when…

Linear Mixed-Effects (LME) models are a fundamental tool for modeling clustered data, including cohort studies, longitudinal data analysis, and meta-analysis. The design and analysis of variable selection methods for LMEs is considerably…

Methodology · Statistics 2022-09-28 Aleksandr Aravkin , James Burke , Aleksei Sholokhov , Peng Zheng

Joint models for a wide class of response variables and longitudinal measurements consist on a mixed-effects model to fit longitudinal trajectories whose random effects enter as covariates in a generalized linear model for the primary…

Methodology · Statistics 2014-07-03 Rolando De la Cruz , Cristian Meza , Ana Arribas-Gil , Raymond J. Carroll

This study examines the feasibility of applying large language models (LLMs) for forecasting the impact of traffic incidents on the traffic flow. The use of LLMs for this task has several advantages over existing machine learning-based…

Artificial Intelligence · Computer Science 2025-07-08 George Jagadeesh , Srikrishna Iyer , Michal Polanowski , Kai Xin Thia

Background: Linear mixed-effects models are central for analyzing longitudinal continuous data, yet many learners meet them as scattered formulas or software output rather than as a coherent workflow. There is a need for a single,…

Methodology · Statistics 2025-11-19 Sunday A. Adetunji

Multivariate data occurs in a wide range of fields, with ever more flexible model specifications being proposed, often within a multivariate generalised linear mixed effects (MGLME) framework. In this article, we describe an extended…

Methodology · Statistics 2017-10-09 Michael J. Crowther

This study was sparked by an extensive longitudinal dataset focusing on HIV CD4 T$^+$ cell counts from Livingstone district, Zambia. Analysis of the corresponding histogram plots reveals an absence of symmetry in the marginal distributions,…

Methodology · Statistics 2025-05-28 Subhajit Chattopadhyay

In machine learning and data mining, linear models have been widely used to model the response as parametric linear functions of the predictors. To relax such stringent assumptions made by parametric linear models, additive models consider…

Machine Learning · Statistics 2017-10-18 Sheng Chen , Arindam Banerjee

Modeling of high-dimensional data is very important to categorize different classes. We develop a new mixture model called Multinomial cluster-weighted model (MCWM). We derive the identifiability of a general class of MCWM. We estimate the…

Methodology · Statistics 2022-08-25 Kehinde Olobatuyi , Oludare Ariyo

Finite mixtures of regressions with fixed covariates are a commonly used model-based clustering methodology to deal with regression data. However, they assume assignment independence, i.e. the allocation of data points to the clusters is…

Methodology · Statistics 2021-04-27 Salvatore D. Tomarchio , Paul D. McNicholas , Antonio Punzo

We study optimization for losses that admit a variance-mean scale-mixture representation. Under this representation, each EM iteration is a weighted least squares update in which latent variables determine observation and parameter weights;…

Computation · Statistics 2026-02-17 Nick Polson , Vadim Sokolov

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…

Methodology · Statistics 2023-01-23 Lars Lau Raket

Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, fitting mvLMMs is computationally non-trivial,…

Quantitative Methods · Quantitative Biology 2013-09-13 Xiang Zhou , Matthew Stephens

Quantifying changes in the probability and magnitude of extreme flooding events is key to mitigating their impacts. While hydrodynamic data are inherently spatially dependent, traditional spatial models such as Gaussian processes are poorly…

Methodology · Statistics 2024-05-06 Reetam Majumder , Brian J. Reich , Benjamin A. Shaby

This paper investigates the estimation of the double autoregressive (DAR) model in the presence of skewed and heavy-tailed innovations. We propose a novel Normal Mixture Quasi-Maximum Likelihood Estimation (NM-QMLE) method to address the…

Methodology · Statistics 2025-05-30 Zhao Chen , Chen Shi , Christina Dan Wang

Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model…

Computation · Statistics 2014-06-24 Douglas Bates , Martin Mächler , Ben Bolker , Steve Walker

We extend the linear mixed-effects state model to accommodate the correlated individuals and investigate its parameter and state estimation based on disturbance smoothing in this paper. For parameter estimation, EM and score based…

Methodology · Statistics 2014-09-03 Jie Zhou , Aiping Tang

This work proposes a machine-learning framework for modeling the error incurred by approximate solutions to parameterized dynamical systems. In particular, we extend the machine-learning error models (MLEM) framework proposed in Ref. 15 to…

Numerical Analysis · Mathematics 2020-04-22 Eric J. Parish , Kevin T. Carlberg

In response to the challenge of accommodating non-Gaussian behaviour in data, the shifted asymmetric Laplace (SAL) cluster-weighted model (SALCWM) is introduced as a model-based method for jointly clustering responses and random covariates…

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