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Brain networks exhibit complications such as noise, neuron failures, and partial synaptic connectivity. These can make it difficult to model and analyze their behavior. This paper describes a way to address this difficulty, namely, breaking…

Data Structures and Algorithms · Computer Science 2025-03-25 Nancy Lynch

Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several…

Quantitative Methods · Quantitative Biology 2018-02-06 M. De Domenico

Understanding whether large language models (LLMs) and the human brain converge on similar computational principles remains a fundamental and important question in cognitive neuroscience and AI. Do the brain-like patterns observed in LLMs…

Computation and Language · Computer Science 2025-12-03 Yu Lei , Xingyang Ge , Yi Zhang , Yiming Yang , Bolei Ma

The principled design and discovery of biologically- and physically-informed models of neuronal dynamics has been advancing since the mid-twentieth century. Recent developments in artificial intelligence (AI) have accelerated this progress.…

Neurons and Cognition · Quantitative Biology 2021-12-24 Mahta Ramezanian Panahi , Germán Abrevaya , Jean-Christophe Gagnon-Audet , Vikram Voleti , Irina Rish , Guillaume Dumas

Despite the recent success of neural network models in mimicking animal performance on visual perceptual tasks, critics worry that these models fail to illuminate brain function. We take it that a central approach to explanation in systems…

Neurons and Cognition · Quantitative Biology 2021-04-13 Rosa Cao , Daniel Yamins

Recent advancements in Large Language Models (LLMs) have greatly enhanced natural language understanding and content generation. However, these models primarily operate in disembodied digital environments and lack interaction with the…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Wenbing Tang , Meilin Zhu , Fenghua Wu , Yang Liu

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Neurons and Cognition · Quantitative Biology 2021-04-15 Rosa Cao , Daniel Yamins

Modeling agent behavior is central to understanding the emergence of complex phenomena in multiagent systems. Prior work in agent modeling has largely been task-specific and driven by hand-engineering domain-specific prior knowledge. We…

Multiagent Systems · Computer Science 2018-08-02 Aditya Grover , Maruan Al-Shedivat , Jayesh K. Gupta , Yura Burda , Harrison Edwards

We try to perform geometrization of psychology by representing mental states, <<ideas>>, by points of a metric space, <<mental space>>. Evolution of ideas is described by dynamical systems in metric mental space. We apply the mental space…

Artificial Intelligence · Computer Science 2010-11-30 Andrei Khrennikov

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

Quantitative Methods · Quantitative Biology 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

Connecting brain and behavior is a longstanding issue in the areas of behavioral science, artificial intelligence, and neurobiology. As is standard among models of artificial and biological neural networks, an analogue of the fully mature…

Neurons and Cognition · Quantitative Biology 2022-05-12 Stefan Dvoretskii , Ziyi Gong , Ankit Gupta , Jesse Parent , Bradly Alicea

For decades, neuroscientists and computer scientists have pursued a shared ambition: to understand intelligence and build it. Modern artificial neural networks now rival humans in language, perception, and reasoning, yet it is still largely…

Artificial Intelligence · Computer Science 2025-10-29 Silin Chen , Yuzhong Chen , Zifan Wang , Junhao Wang , Zifeng Jia , Keith M Kendrick , Tuo Zhang , Lin Zhao , Dezhong Yao , Tianming Liu , Xi Jiang

Shapes of cognition is a new conceptual paradigm for the computational cognitive modeling of Language-Endowed Intelligent Agents (LEIAs). Shapes are remembered constellations of sensory, linguistic, conceptual, episodic, and procedural…

Artificial Intelligence · Computer Science 2025-09-17 Marjorie McShane , Sergei Nirenburg , Sanjay Oruganti , Jesse English

Complex reasoning in tool-augmented agent frameworks is inherently long-horizon, causing reasoning traces and transient tool artifacts to accumulate and strain the bounded working context of large language models. Without explicit memory…

Artificial Intelligence · Computer Science 2026-01-14 Hongjin Qian , Zhao Cao , Zheng Liu

To make progress in science, we often build abstract representations of physical systems that meaningfully encode information about the systems. The representations learnt by most current machine learning techniques reflect statistical…

AI agents -- systems that combine foundation models with reasoning, planning, memory, and tool use -- are rapidly becoming a practical interface between natural-language intent and real-world computation. This survey synthesizes the…

Artificial Intelligence · Computer Science 2026-01-06 Bin Xu

Training and education in human-centered fields require authentic practice, yet realistic simulations of human behavior have remained limited. We present a multi-agent psychological simulation system that models internal cognitive-affective…

Artificial Intelligence · Computer Science 2025-11-05 Xiangen Hu , Jiarui Tong , Sheng Xu

The study of cellular signalling pathways and their deregulation in disease states, such as cancer, is a large and extremely complex task. Indeed, these systems involve many parts and processes but are studied piecewise and their…

Artificial Intelligence · Computer Science 2016-08-22 Adrien Basso-Blandin , Walter Fontana , Russ Harmer

Intelligent biological systems are characterized by their embodiment in a complex environment and the intimate interplay between their nervous systems and the nonlinear mechanical properties of their bodies. This coordination, in which the…

Machine Learning · Computer Science 2023-02-02 Deniz Oktay , Mehran Mirramezani , Eder Medina , Ryan P. Adams

Neuro-symbolic AI is an effective method for improving the overall performance of AI models by combining the advantages of neural networks and symbolic learning. However, there are differences between the two in terms of how they process…

Artificial Intelligence · Computer Science 2024-11-08 Xin Zhang , Victor S. Sheng