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Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data,…

Medical Physics · Physics 2020-03-02 Md Ashequr Rahman , Richard Laforest , Abhinav K. Jha

Attenuation compensation (AC) is a pre-requisite for reliable quantification and beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT). Typical AC methods require the availability of an attenuation…

Medical Physics · Physics 2021-02-12 Zitong Yu , Md Ashequr Rahman , Thomas Schindler , Richard Laforest , Abhinav K. Jha

Recent developments in artificial intelligence technology have enabled new developments that can improve attenuation and scatter correction in PET and SPECT. These technologies will enable the use of accurate and quantitative imaging…

Medical Physics · Physics 2021-08-30 Alan B. McMillan , Tyler J. Bradshaw

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Single-photon avalanche diodes (SPADs) have emerged as a promising candidate for optical wireless communication (OWC) owing to their ultra-high sensitivity and singlephoton detection capability. However, under strong background radiation or…

Signal Processing · Electrical Eng. & Systems 2026-05-28 Chen Wang , Zhiyong Xu , Jingyuan Wang , Jianhua Li , Weifeng Mou , Huatao Zhu

Attenuation and scatter correction (AC) is crucial for quantitative Positron Emission Tomography (PET) imaging. Recently, direct application of AC in the image domain using deep learning approaches has been proposed for the hybrid PET/MR…

Medical Physics · Physics 2022-06-30 Reza Jahangir , Alireza Kamali-Asl , Hossein Arabi

99m-Tc Ethyl-Cysteinate-Dimer SPECT and MR imaging play a significant role in diagnosing anosmia. In this study, two-tissue class and three-tissue class attenuation maps (2C-MR and 3CMR) obtained from MR images were compared with CT-based…

Objective: In this work, we set out to investigate the accuracy of direct attenuation correction (AC) in the image domain for the myocardial perfusion SPECT imaging (MPI-SPECT) using two residual (ResNet) and UNet deep convolutional neural…

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Recent advances in computationally efficient non-myopic Bayesian optimization (BO) improve query efficiency over traditional myopic methods like expected improvement while only modestly increasing computational cost. These advances have…

Machine Learning · Statistics 2021-12-07 Yunxiang Zhang , Xiangyu Zhang , Peter I. Frazier

Aberration correction is an important aspect of modern high-resolution scanning transmission electron microscopy. Most methods of aligning aberration correctors require specialized sample regions and are unsuitable for fine-tuning…

Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…

Medical Physics · Physics 2021-09-21 Tengbo Lyu , Jiadong Zhang , Zijian Gao , Changchun Yang , Feng Gao , Fei Gao

Aberration-corrected Scanning Transmission Electron Microscopy (STEM) has become an essential tool in understanding materials at the atomic scale. However, tuning the aberration corrector to produce a sub-{\AA}ngstr\"om probe is a complex…

The purpose of this work is to provide a fast and accurate scatter artifacts correction algorithm for cone beam CT (CBCT) imaging. The method starts with an estimation of coarse scatter profiles for a set of CBCT data in either image domain…

Medical Physics · Physics 2016-04-27 Wei Zhao , Don Vernekohl , Jun Zhu , Luyao Wang , Lei Xing

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen

Attenuation artifacts remain a significant challenge in cardiac Myocardial Perfusion Imaging (MPI) using Single-Photon Emission Computed Tomography (SPECT), often compromising diagnostic accuracy and reducing clinical interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Trung Kien Pham , Hoang Minh Vu , Anh Duc Chu , Dac Thai Nguyen , Trung Thanh Nguyen , Thao Nguyen Truong , Mai Hong Son , Thanh Trung Nguyen , Phi Le Nguyen

Purpose: Photon counting (PC) computed tomography (CT) can provide material selective CT imaging at lowest patient dose but it suffers from suboptimal count rate. A dynamic beam attenuator (DBA) can help with count rate by modulating x-ray…

Medical Physics · Physics 2016-12-23 Haluk Atak , Polad M. Shikhaliev

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are being investigated as biomarkers to diagnose, assess disease…

Attenuation compensation (AC) is beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). However, traditional AC methods require the availability of a transmission…

Medical Physics · Physics 2023-03-21 Zitong Yu , Md Ashequr Rahman , Craig K. Abbey , Barry A. Siegel , Abhinav K. Jha
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