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We propose a travelling-wave perturbation method to control the spatiotemporal dynamics in a cardiac model. It is numerically demonstrated that the method can successfully suppress the wave instability (alternans in action potential…

Tissues and Organs · Quantitative Biology 2009-11-10 Peng-Ye Wang , Ping Xie , Hua-Wei Yin

Control strategy for suppression of spiral-wave in a 2-D model of an excitable media is developed with application to the cardiac system. The controller which incorporates a finite number of actuators (electrodes) assures the establishment…

Optimization and Control · Mathematics 2014-10-03 Yelena Smagina , Moshe Sheintuch

Turbulence of scroll waves is a sort of spatio-temporal chaos that exists in three-dimensional excitable media. Cardiac tissue and the Belousov-Zhabotinsky reaction are examples of such media. In cardiac tissue, chaotic behaviour is…

Pattern Formation and Solitons · Physics 2009-11-13 S. W. Morgan , I. V. Biktasheva , V. N. Biktashev

On the basis of a quite realistic ionic Fenton--Karma model of the cardiac tissue we consider the problem of defibrillation by a local weak forcing. In contrast to other systems, this model accurately reproduces the most essential…

Chaotic Dynamics · Physics 2007-05-23 Ekaterina Zhuchkova , Boris Radnaev , Alexander Loskutov

The dynamics of activation waves in excitable media can give rise to spiral turbulence, the resulting spatiotemporal chaos being associated with empirical biological phenomena such as life-threatening disturbances in the natural rhythm of…

Chaotic Dynamics · Physics 2008-04-07 S. Sridhar , Sitabhra Sinha

Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart makes it incapable of any…

Chaotic Dynamics · Physics 2009-11-07 Sitabhra Sinha , Ashwin Pande , Rahul Pandit

While spiral wave breakup has been implicated in the emergence of atrial fibrillation, its role in maintaining this complex type of cardiac arrhythmia is less clear. We used the Karma model of cardiac excitation to investigate the dynamical…

Tissues and Organs · Quantitative Biology 2017-10-11 Christopher D Marcotte , Roman O Grigoriev

A spiral wave is a macroscopic dynamic of excitable media that plays an important role in several distinct systems, including the Belousov-Zhabotinsky reaction, seizures in the brain, and lethal arrhythmia in the heart. Because spiral wave…

Pattern Formation and Solitons · Physics 2018-02-02 Hiroshi Ashikaga , Ryan G. James

Excitable media are systems which are at rest in the absence of external input but which respond to a sufficiently strong stimulus by sending a wave of "excitation" across the medium. Examples include cardiac and cortical tissue, and in…

Quantitative Methods · Quantitative Biology 2021-01-01 S. P. Hastings , M. M Sussman

Excitable media are a generic class of models used to simulate a wide variety of natural systems including cardiac tissue. Propagation of excitation waves in this medium results in the formation of characteristic patterns such as rotating…

Chaotic Dynamics · Physics 2011-11-10 Sitabhra Sinha , S. Sridhar

Turbulence control in the two-dimensional complex Ginzburg-Landau equation is investigated. A new approach is proposed for the control purpose. In the presence of a small spiral wave seed initiation, a fully developed turbulence can be…

Soft Condensed Matter · Physics 2009-11-10 Hong Zhang , Bambi Hu , Gang Hu , Qi Ouyang , J. Kurths

In a weakly excitable medium, characterized by a large threshold stimulus, the free end of an isolated broken plane wave (wave tip) can either rotate (steadily or unsteadily) around a large excitable core, thereby producing a spiral…

Soft Condensed Matter · Physics 2009-10-31 Vincent Hakim , Alain Karma

In this paper, we study the traveling wave solutions to the density-suppressed motility model describing the ``self-trapping'' mechanism that induces spatio-temporal pattern formations observed in the experiment. We establish the existence…

Analysis of PDEs · Mathematics 2020-06-24 Jing Li , Zhi-An Wang

Trapping and un-trapping of spiral tips in a two-dimensional homogeneous excitable medium with local small-world connections is studied by numerical simulation. In a homogeneous medium which can be simulated with a lattice of regular…

Pattern Formation and Solitons · Physics 2009-11-10 Xiaonan Wang , Ying Lu , Minxi Jiang , Qi Ouyang

A universal approach is proposed for suppression of collective synchrony in a large population of interacting rhythmic units. We demonstrate that provided that the internal coupling is weak, stabilization of overall oscillations with…

Adaptation and Self-Organizing Systems · Physics 2011-11-08 Ming Luo , Yongjun Wu

During episodes of atrial fibrillation, the heart's electrical activity becomes disorganized and shows fragmenting spiral waves. To systematically address how this pattern terminates using spatially extended simulations exceeds current…

Tissues and Organs · Quantitative Biology 2019-01-16 David Vidmar , Wouter-Jan Rappel

Spiral waves are self-repeating waves that can form in excitable media, propagating outward from their center in a spiral pattern. Spiral waves have been observed in different natural phenomena and have been linked to medical conditions…

Cellular Automata and Lattice Gases · Physics 2020-08-11 Vincent Vangelista , Karl Amjad-Ali , Minhyeok Kwon , Paulo H. Acioli

The physical mechanism on meridians (acupuncture lines) is studied and a theoretical model is proposed. The meridians are explained as an alternating system responsible for the integration and the regulation of life in addition to the…

Medical Physics · Physics 2021-06-09 Liaofu Luo , Fengqi Bao

Spiral waves arise in many biological, chemical, and physiological systems. The kinematical model can be used to describe the motion of the spiral arms approximated as curves in the plane. For this model, there appeared some results in the…

Dynamical Systems · Mathematics 2007-05-23 Chu-Pin Lo , Nedialko S. Nedialkov , Juan-Ming Yuan

Controlling spatiotemporal chaos in excitable media by applying low-amplitude perturbations {\em locally} is of immediate applicability, e.g., in treating ventricular fibrillation, a fatal disturbance in the normal rhythmic functioning of…

Chaotic Dynamics · Physics 2007-05-23 Johannes Breuer , Sitabhra Sinha
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