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Suppose that we intend to perform an experiment consisting of a set of independent trials. The mean value of the response of each trial is assumed to be equal to the sum of the effect of the treatment selected for the trial, and some…

Statistics Theory · Mathematics 2016-12-21 Samuel Rosa , Radoslav Harman

In several applications such as databases, planning, and sensor networks, parameters such as selectivity, load, or sensed values are known only with some associated uncertainty. The performance of such a system (as captured by some…

Data Structures and Algorithms · Computer Science 2010-01-28 Sudipto Guha , Kamesh Munagala

Adaptive designs have been proposed for clinical trials in which the nuisance parameters or alternative of interest are unknown or likely to be misspecified before the trial. Whereas most previous works on adaptive designs and mid-course…

Methodology · Statistics 2011-05-18 Jay Bartroff , Tze Leung Lai

There is wide interest in studying how the distribution of a continuous response changes with a predictor. We are motivated by environmental applications in which the predictor is the dose of an exposure and the response is a health…

Methodology · Statistics 2018-05-10 Antonio Canale , Daniele Durante , David Dunson

Indirect experiments provide a valuable framework for estimating treatment effects in situations where conducting randomized control trials (RCTs) is impractical or unethical. Unlike RCTs, indirect experiments estimate treatment effects by…

Machine Learning · Computer Science 2023-12-06 Yash Chandak , Shiv Shankar , Vasilis Syrgkanis , Emma Brunskill

Following SimCSE, contrastive learning based methods have achieved the state-of-the-art (SOTA) performance in learning sentence embeddings. However, the unsupervised contrastive learning methods still lag far behind the supervised…

Computation and Language · Computer Science 2022-06-07 Wei Wang , Liangzhu Ge , Jingqiao Zhang , Cheng Yang

Dealing with distribution shifts is one of the central challenges for modern machine learning. One fundamental situation is the covariate shift, where the input distributions of data change from training to testing stages while the…

Machine Learning · Computer Science 2024-05-28 Yu-Jie Zhang , Zhen-Yu Zhang , Peng Zhao , Masashi Sugiyama

Analysis of variance (ANOVA) reveals some disadvantages, such as non-robustness against heteroscedastic or non-normal errors and using difference to overall mean as effect sizes only. As an alternative the multiple contrast test comparing…

Methodology · Statistics 2023-03-27 Ludwig A. Hothorn

Comparative effectiveness research frequently addresses a time-to-event outcome and can require unique considerations in the presence of treatment noncompliance. Motivated by the challenges in addressing noncompliance in the ADAPTABLE…

Methodology · Statistics 2025-08-19 Chao Cheng , Bo Liu , Lisa Wruck , Fan Li , Fan Li

This paper addresses the problem of deciding whether the dose response relationships between subgroups and the full population in a multi-regional trial are similar to each other. Similarity is measured in terms of the maximal deviation…

Statistics Theory · Mathematics 2024-04-30 Holger Dette , Lukas Koletzko , Frank Bretz

Reliable detection of anomalies is crucial when deploying machine learning models in practice, but remains challenging due to the lack of labeled data. To tackle this challenge, contrastive learning approaches are becoming increasingly…

Computer Vision and Pattern Recognition · Computer Science 2021-07-19 Puck de Haan , Sindy Löwe

Recently, contrastive self-supervised learning has become a key component for learning visual representations across many computer vision tasks and benchmarks. However, contrastive learning in the context of domain adaptation remains…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Mamatha Thota , Georgios Leontidis

Adaptive attacks have (rightfully) become the de facto standard for evaluating defenses to adversarial examples. We find, however, that typical adaptive evaluations are incomplete. We demonstrate that thirteen defenses recently published at…

Machine Learning · Computer Science 2020-10-26 Florian Tramer , Nicholas Carlini , Wieland Brendel , Aleksander Madry

Estimation of the high-dimensional banded covariance matrix is widely used in multivariate statistical analysis. To ensure the validity of estimation, we aim to test the hypothesis that the covariance matrix is banded with a certain…

Methodology · Statistics 2022-04-26 Xiaoyi Wang , Gongjun Xu , Shurong Zheng

We propose SparseContrast, a new framework that merges dynamic sparse attention with contrastive learning for medical imaging, with a focus on chest X-ray disease detection in low-data settings. Traditional contrastive learning methods rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Paarth Prasad , Ruchika Malhotra

A new gradient-based adaptive sampling method is proposed for design of experiments applications which balances space filling, local refinement, and error minimization objectives while reducing reliance on delicate tuning parameters. High…

Methodology · Statistics 2024-05-09 Lucas Caparini , Gwynn J. Elfring , Mauricio Ponga

We consider sequential hypothesis testing between two quantum states using adaptive and non-adaptive strategies. In this setting, samples of an unknown state are requested sequentially and a decision to either continue or to accept one of…

Quantum Physics · Physics 2023-03-07 Yonglong Li , Vincent Y. F. Tan , Marco Tomamichel

In randomized clinical trials, adjustments for baseline covariates at both design and analysis stages are highly encouraged by regulatory agencies. A recent trend is to use a model-assisted approach for covariate adjustment to gain…

Methodology · Statistics 2021-07-14 Ting Ye , Jun Shao , Yanyao Yi , Qingyuan Zhao

This study reveals the inherent tolerance of contrastive learning (CL) towards sampling bias, wherein negative samples may encompass similar semantics (\eg labels). However, existing theories fall short in providing explanations for this…

Machine Learning · Computer Science 2023-10-18 Junkang Wu , Jiawei Chen , Jiancan Wu , Wentao Shi , Xiang Wang , Xiangnan He

Saliency methods are widely used to visualize which input features are deemed relevant to a model's prediction. However, their visual plausibility can obscure critical limitations. In this work, we propose a diagnostic test for class…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Dane Williamson , Yangfeng Ji , Matthew Dwyer
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