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Because of the complicated mechanism of ankle injury, it is very difficult to diagnose ankle fracture in clinic. In order to simplify the process of fracture diagnosis, an automatic diagnosis model of ankle fracture was proposed. Firstly, a…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Hongzhi Liu , Guicheng Li , Jiacheng Nie , Hui Tang , Chunfeng Yang , Qianjin Feng , Hailin Xu , Yang Chen

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Advances in deep learning have opened an era of abundant and accurate predicted protein structures; however, similar progress in protein ensembles has remained elusive. This review highlights several recent research directions towards…

Biomolecules · Quantitative Biology 2025-09-23 Bowen Jing , Bonnie Berger , Tommi Jaakkola

The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst…

Machine Learning · Computer Science 2025-05-30 Niamh Belton , Aonghus Lawlor , Kathleen M. Curran

This study evaluates a multimodal machine learning framework for predicting treatment outcomes in intracranial aneurysms (IAs). Combining angiographic parametric imaging (API), patient biomarkers, and disease morphology, the framework aims…

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 David Butler , Adrian Hilton , Gustavo Carneiro

Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively…

Artificial Intelligence · Computer Science 2023-10-31 Adam White , Margarita Saranti , Artur d'Avila Garcez , Thomas M. H. Hope , Cathy J. Price , Howard Bowman

We aim at the solution of inverse problems in imaging, by combining a penalized sparse representation of image patches with an unconstrained smooth one. This allows for a straightforward interpretation of the reconstruction. We formulate…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Stanislas Ducotterd , Sebastian Neumayer , Michael Unser

Recent advances in sensing technologies require the design and development of pattern recognition models capable of processing spatiotemporal data efficiently. In this study, we propose a spatially and temporally aware tensor-based neural…

Health care decisions are increasingly informed by clinical decision support algorithms, but these algorithms may perpetuate or increase racial and ethnic disparities in access to and quality of health care. Further complicating the…

Methodology · Statistics 2024-02-28 Solvejg Wastvedt , Joshua Snoke , Denis Agniel , Julie Lai , Marc N. Elliott , Steven C. Martino

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang

Supervised machine learning algorithms, especially in the medical domain, are affected by considerable ambiguity in expert markings. In this study we address the case where the experts' opinion is obtained as a distribution over the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan

The regulatory approval and broad clinical deployment of medical AI have been hampered by the perception that deep learning models fail in unpredictable and possibly catastrophic ways. A lack of statistically rigorous uncertainty…

Machine Learning · Computer Science 2022-07-07 Charles Lu , Anastasios N. Angelopoulos , Stuart Pomerantz

Tabular datasets are widely used in scientific disciplines such as biology. While these disciplines have already adopted AI methods to enhance their findings and analysis, they mainly use tree-based methods due to their interpretability. At…

Machine Learning · Computer Science 2025-04-16 Salvatore Raieli , Nathalie Jeanray , Stéphane Gerart , Sebastien Vachenc , Abdulrahman Altahhan

Recent studies have demonstrated advantages of information fusion based on sparsity models for multimodal classification. Among several sparsity models, tree-structured sparsity provides a flexible framework for extraction of…

Computer Vision and Pattern Recognition · Computer Science 2015-02-04 Soheil Bahrampour , Asok Ray , Nasser M. Nasrabadi , Kenneth W. Jenkins

Parkinson's disease (PD) is projected to increase substantially due to population aging, making early diagnosis increasingly important, as timely detection may delay progression and reduce long-term complications. Retinal microvasculature…

Designing strong and robust bio-inspired structures requires an understanding of how function arises from the architecture and geometry of materials found in nature. We draw from trabecular bone, a lightweight bone tissue that exhibits a…

Biological Physics · Physics 2019-10-09 Chantal Nguyen , Darin Peetz , Ahmed E. Elbanna , Jean M. Carlson

This chapter presents the investigations and the results of feature learning using convolutional neural networks to automatically assess knee osteoarthritis (OA) severity and the associated clinical and diagnostic features of knee OA from…

Computer Vision and Pattern Recognition · Computer Science 2019-08-26 Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O' Connor