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The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

There is a growing trend in molecular and synthetic biology of using mechanistic (non machine learning) models to design biomolecular networks. Once designed, these networks need to be validated by experimental results to ensure the…

Quantitative Methods · Quantitative Biology 2020-11-26 Ruby Sedgwick , John Goertz , Molly Stevens , Ruth Misener , Mark van der Wilk

In networks of dynamic systems, one challenge is to identify the interconnection structure on the basis of measured signals. Inspired by a Bayesian approach in [1], in this paper, we explore a Bayesian model selection method for identifying…

Systems and Control · Computer Science 2019-03-18 Shengling Shi , Giulio Bottegal , Paul M. J. Van den Hof

This paper studies the optimal state estimation problem for interconnected systems. Each subsystem can obtain its own measurement in real time, while, the measurements transmitted between the subsystems suffer from random delay. The optimal…

Systems and Control · Electrical Eng. & Systems 2023-05-03 Yan Wang , Junlin Xiong , Zaiyue Yang , Rong Su

Using mathematical models to assist in the interpretation of experiments is becoming increasingly important in research across applied mathematics, and in particular in biology and ecology. In this context, accurate parameter estimation is…

Statistics Theory · Mathematics 2025-04-29 Jie Qi , Ruth E. Baker

Understanding the dynamics of complex systems is a central task in many different areas ranging form biology via epidemics to economics and engineering. Unexpected behaviour of dynamic systems or even systems failure is sometimes difficult…

Optimization and Control · Mathematics 2020-06-11 Dominik Kahl , Andreas Weber , Maik Kschischo

We consider the utilization of a computational model to guide the optimal acquisition of experimental data to inform the stochastic description of model input parameters. Our formulation is based on the recently developed consistent…

Computation · Statistics 2021-05-04 Scott N. Walsh , Tim M. Wildey , John D. Jakeman

The increasing penetration of intermittent distributed energy resources in power networks calls for novel planning and control methodologies which hinge on detailed knowledge of the grid. However, reliable information concerning the system…

Systems and Control · Electrical Eng. & Systems 2021-09-21 Emanuele Fabbiani , Pulkit Nahata , Giuseppe De Nicolao , Giancarlo Ferrari-Trecate

Recently there has been a lot of interest in monitoring and identifying changes in dynamic networks, which has led to the development of a variety of monitoring methods. Unfortunately, these methods have not been systematically compared;…

Computation · Statistics 2019-05-27 Lisha Yu , Inez M. Zwetsloot , Nathaniel T. Stevens , James D. Wilson , Kwok Leung Tsui

This paper investigates the state estimation problem for a class of complex networks, in which the dynamics of each node is subject to Gaussian noise, system uncertainties and nonlinearities. Based on a regularized least-squares approach,…

Systems and Control · Electrical Eng. & Systems 2021-03-16 Peihu Duan , Qishao Wang , Zhisheng Duan , Guanrong Chen

As electrical generation becomes more distributed and volatile, and loads become more uncertain, controllability of distributed energy resources (DERs), regardless of their ownership status, will be necessary for grid reliability. Grid…

Systems and Control · Electrical Eng. & Systems 2024-10-22 Adam Lechowicz , Joshua Comden , Andrey Bernstein

In this paper, we study networks of positive linear systems subject to time-invariant and random uncertainties. We present linear matrix inequalities for checking the stability of the whole network around the origin with prescribed…

Optimization and Control · Mathematics 2016-11-09 Masaki Ogura , Victor M. Preciado

Optimal operation of distribution grid resources relies on accurate estimation of its state and topology. Practical estimation of such quantities is complicated by the limited presence of real-time meters. This paper discusses a theoretical…

Systems and Control · Computer Science 2020-01-06 Deepjyoti Deka , Michael Chertkov , Scott Backhaus

The dynamics of systems of interacting agents is determined by the structure of their coupling network. The knowledge of the latter is, therefore, highly desirable, for instance, to develop efficient control schemes, to accurately predict…

Adaptation and Self-Organizing Systems · Physics 2021-10-13 Melvyn Tyloo , Robin Delabays , Philippe Jacquod

In this work we study the interplay between the dynamics of a model of diffusion governed by a mechanism of imitation and its underlying structure. The dynamics of the model can be quantified by a macroscopic observable which permits the…

Statistical Mechanics · Physics 2009-11-10 Mateu Llas , Pablo M. Gleiser , Albert Diaz-Guilera , Conrad J. Perez

The problem of quickest detection of dynamic events in networks is studied. At some unknown time, an event occurs, and a number of nodes in the network are affected by the event, in that they undergo a change in the statistics of their…

Signal Processing · Electrical Eng. & Systems 2018-07-18 Shaofeng Zou , Venugopal V. Veeravalli , Jian Li , Don Towsley

We present a systematic method for designing distributed generation and demand control schemes for secondary frequency regulation in power networks such that stability and an economically optimal power allocation can be guaranteed. A…

Optimization and Control · Mathematics 2017-03-03 Andreas Kasis , Nima Monshizadeh , Eoin Devane , Ioannis Lestas

This paper traces the strong relations between experimental design and control, such as the use of optimal inputs to obtain precise parameter estimation in dynamical systems and the introduction of suitably designed perturbations in…

Optimization and Control · Mathematics 2008-03-03 Luc Pronzato

This work presents a detailed covariance and correlation matrix analysis for experimentally measured cross sections obtained using the activation technique. Both statistical and systematic contributions to the covariance matrix were…

Nuclear Theory · Physics 2026-04-01 Tanmoy Bar

The problem of resource allocation of nonlinear networked control systems is investigated, where, unlike the well discussed case of triggering for stability, the objective is optimal triggering. An approximate dynamic programming approach…

Systems and Control · Computer Science 2014-12-19 Ali Heydari