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Genome-scale gene networks contain regulatory genes called hubs that have many interaction partners. These genes usually play an essential role in gene regulation and cellular processes. Despite recent advancements in high-throughput…

Quantitative Methods · Quantitative Biology 2017-10-06 Nurgazy Sulaimanov , Sunil Kumar , Frédéric Burdet , Mark Ibberson , Marco Pagni , Heinz Koeppl

In network tomography, one goal is to identify a small set of failed links in a network, by sending a few packets through the network and seeing which reach their destination. This problem can be seen as a variant of combinatorial group…

Information Theory · Computer Science 2018-09-12 Bruce Spang , Mary Wootters

Penalized regression methods, most notably the lasso, are a popular approach to analyzing high-dimensional data. An attractive property of the lasso is that it naturally performs variable selection. An important area of concern, however, is…

Methodology · Statistics 2026-05-13 Ryan Miller , Patrick Breheny

The graphical lasso (glasso) is an $l_1$ penalised likelihood estimator for a Gaussian precision matrix. A benefit of the glasso is that it exists even when the sample covariance matrix is not positive definite but only positive…

Statistics Theory · Mathematics 2025-05-27 Jack Storror Carter

Lasso is a popular and efficient approach to simultaneous estimation and variable selection in high-dimensional regression models. In this paper, a robust LAD-lasso method for multiple outcomes is presented that addresses the challenges of…

Methodology · Statistics 2022-12-02 Jyrki Möttönen , Tero Lähderanta , Janne Salonen , Mikko J. Sillanpää

In recent years, network models have gained prominence for their ability to capture complex associations. In statistical omics, networks can be used to model and study the functional relationships between genes, proteins, and other types of…

Methodology · Statistics 2023-06-21 Camilla Lingjærde , Sylvia Richardson

A conditional independence graph is a concise representation of pairwise conditional independence among many variables. Graphical Random Forests (GRaFo) are a novel method for estimating pairwise conditional independence relationships among…

We consider adaptive estimation and statistical inference for high-dimensional graph-based linear models. In our model, the coordinates of regression coefficients correspond to an underlying undirected graph. Furthermore, the given graph…

Statistics Theory · Mathematics 2020-01-30 Duzhe Wang , Po-Ling Loh

We study the property of the Fused Lasso Signal Approximator (FLSA) for estimating a blocky signal sequence with additive noise. We transform the FLSA to an ordinary Lasso problem. By studying the property of the design matrix in the…

Machine Learning · Statistics 2012-11-26 Junyang Qian , Jinzhu Jia

I develop an algorithm to produce the piecewise quadratic that computes leave-one-out cross-validation for the lasso as a function of its hyperparameter. The algorithm can be used to find exact hyperparameters that optimize leave-one-out…

Machine Learning · Statistics 2025-11-04 Ryan Burn

Federated learning, where algorithms are trained across multiple decentralized devices without sharing local data, is increasingly popular in distributed machine learning practice. Typically, a graph structure $G$ exists behind local…

Machine Learning · Statistics 2022-09-20 Huiyuan Wang , Xuyang Zhao , Wei Lin

The precision matrix that encodes conditional linear dependency relations among a set of variables forms an important object of interest in multivariate analysis. Sparse estimation procedures for precision matrices such as the graphical…

Methodology · Statistics 2023-03-09 Gaëtan Louvet , Jakob Raymaekers , Germain Van Bever , Ines Wilms

We consider the problem of testing graph cluster structure: given access to a graph $G=(V, E)$, can we quickly determine whether the graph can be partitioned into a few clusters with good inner conductance, or is far from any such graph?…

Data Structures and Algorithms · Computer Science 2018-09-19 Ashish Chiplunkar , Michael Kapralov , Sanjeev Khanna , Aida Mousavifar , Yuval Peres

The time-evolving precision matrix of a piecewise-constant Gaussian graphical model encodes the dynamic conditional dependency structure of a multivariate time-series. Traditionally, graphical models are estimated under the assumption that…

Methodology · Statistics 2017-11-01 Alexander J. Gibberd , James D. B. Nelson

Statistical inference on graphs is a burgeoning field in the applied and theoretical statistics communities, as well as throughout the wider world of science, engineering, business, etc. In many applications, we are faced with the reality…

Machine Learning · Statistics 2014-07-22 Carey E. Priebe , Daniel L. Sussman , Minh Tang , Joshua T. Vogelstein

Graphical modeling explores dependences among a collection of variables by inferring a graph that encodes pairwise conditional independences. For jointly Gaussian variables, this translates into detecting the support of the precision…

Methodology · Statistics 2018-02-16 Shota Katayama , Hironori Fujisawa , Mathias Drton

We consider the problems of variable selection and estimation in nonparametric additive regression models for high-dimensional data. In recent years, several methods have been proposed to model nonlinear relationships when the number of…

Methodology · Statistics 2013-10-07 Linn Cecilie Bergersen , Kukatharmini Tharmaratnam , Ingrid K. Glad

Graph embedding techniques have been increasingly deployed in a multitude of different applications that involve learning on non-Euclidean data. However, existing graph embedding models either fail to incorporate node attribute information…

Machine Learning · Computer Science 2021-06-22 Chenhui Deng , Zhiqiang Zhao , Yongyu Wang , Zhiru Zhang , Zhuo Feng

Graph neural networks (GNNs) have become essential tools for analyzing non-Euclidean data across various domains. During training stage, sampling plays an important role in reducing latency by limiting the number of nodes processed,…

Machine Learning · Computer Science 2024-11-11 Yi Li , Zhichun Guo , Guanpeng Li , Bingzhe Li

This paper proposes a penalized composite likelihood method for model selection in colored graphical Gaussian models. The method provides a sparse and symmetry-constrained estimator of the precision matrix, and thus conducts model selection…

Methodology · Statistics 2020-04-06 Qiong Li , Xiaoying Sun , Nanwei Wang