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Cellularized tissue and polymer networks can both transition from floppy to rigid as a function of their control parameters, and, yet, the two systems often mechanically interact, which may affect their respective rigidities. To study this…

Cell Behavior · Quantitative Biology 2020-06-30 Amanda Parker , M. Cristina Marchetti , M. Lisa Manning , J. M. Schwarz

Epithelial tissues play a fundamental role in various morphogenetic events during development and early embryogenesis. Although epithelial monolayers are often modeled as two-dimensional (2D) elastic surfaces, they distinguish themselves…

Soft Condensed Matter · Physics 2020-06-15 Benjamin Loewe , Francesco Serafin , Suraj Shankar , Mark J. Bowick , M. Cristina Marchetti

Shell structures are generally modeled based on kinematic hypotheses, where some of the parameters are preferentially evaluated in a phenomenological manner. In this article, asymptotic analysis against the underlying three-dimensional…

Materials Science · Physics 2025-07-02 Xiwei Pan , Yichao Zhu

In biological tissues, it is now well-understood that mechanical cues are a powerful mechanism for pattern regulation. While much work has focused on interactions between cells and external substrates, recent experiments suggest that cell…

Soft Condensed Matter · Physics 2017-11-01 Michael Czajkowski , Dapeng Bi , M. Lisa Manning , M. Cristina Marchetti

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

Tissues and Organs · Quantitative Biology 2023-03-08 Nen Saito , Shuji Ishihara

We investigate shear-induced crystallization in a very dense flow of mono-disperse inelastic hard spheres. We consider a steady plane Couette flow under constant pressure and neglect gravity. We assume that the granular density is greater…

Soft Condensed Matter · Physics 2009-11-11 Evgeniy Khain , Baruch Meerson

When granular materials with interstitial liquid bridges are sheared in a split-bottom cell, a localized shear band develops, accompanied by a surface elevation. Cohesion, governed by the surface tension of the interstitial liquid, enhances…

Soft Condensed Matter · Physics 2026-01-06 Huzaif Rahim , Thorsten Poeschel , Sudeshna Roy

The similarity in mechanical properties of dense active matter and sheared amorphous solids has been noted in recent years without a rigorous examination of the underlying mechanism. We develop a mean-field model that predicts that their…

Soft Condensed Matter · Physics 2021-08-03 Peter K. Morse , Sudeshna Roy , Elisabeth Agoritsas , Ethan Stanifer , Eric I. Corwin , M. Lisa Manning

The deformation of an elastic micro-capsule in an infinite shear flow is studied numerically using a spectral method. The shape of the capsule and the hydrodynamic flow field are expanded into smooth basis functions. Analytic expressions…

Soft Condensed Matter · Physics 2008-09-03 S. Kessler , R. Finken , U. Seifert

The onset of nonlinear effects in metals, such as plasticity and damage, is strongly influenced by the heterogeneous stress distribution at the grain level. This work is devoted to studying the local stress distribution of shear stresses…

Materials Science · Physics 2022-07-26 Flavia Gehrig , Daniel Wicht , Maximilian Krause , Thomas Böhlke

The rheology of biological tissues is important for their function, and we would like to better understand how single cells control global tissue properties such as tissue fluidity. A confluent tissue can fluidize when cells diffuse by…

Soft Condensed Matter · Physics 2019-05-31 Preeti Sahu , Janice Kang , Gonca Erdemci-Tandogan , M. Lisa Manning

It is well known that jammed soft materials will flow if sheared above their yield stress - think mayonnaise spread on bread - but a complete microscopic description of this seemingly sim- ple process has yet to emerge. What remains elusive…

Soft Condensed Matter · Physics 2016-08-09 Vishwas V. Vasisht , S. K. Dutta , Emanuela Del Gado , Daniel L. Blair

This work investigates the morphological stability of a soft body composed of two heavy elastic layers, attached to a rigid surface and subjected only to the bulk gravity force. Using theoretical and computational tools, we characterize the…

Soft Condensed Matter · Physics 2017-09-21 Davide Riccobelli , Pasquale Ciarletta

The jamming transition, generally manifested by a rapid increase of rigidity under compression (i.e., compression hardening), is ubiquitous in amorphous materials. Here we study shear hardening in deeply annealed frictionless packings…

Soft Condensed Matter · Physics 2023-12-12 Deng Pan , Fanlong Meng , Yuliang Jin

A partially-wetting liquid can deform the underlying elastic substrate upon which it rests. This situation requires the development of theoretical models to describe the wetting forces imparted by the drop onto the solid substrate,…

Soft Condensed Matter · Physics 2014-05-02 Joshua B. Bostwick , Michael Shearer , Karen E. Daniels

Molecular-motor generated active stresses drive the cytoskeleton away from equilibrium, endowing it with tunable mechanical properties that are essential for diverse functions such as cell division and motility[1-5]. Designing analogous…

We investigate the elasticity of unsupported epithelial monolayer and we discover that unlike a thin solid plate, which wrinkles if geometrically incompatible with the underlying substrate, the epithelium may do so even in absence of the…

Soft Condensed Matter · Physics 2023-05-24 Urška Andrenšek , Primož Ziherl , Matej Krajnc

Dry granular materials such as sand, gravel, pills, or agricultural grains, can become rigid when compressed or sheared. At low density, one can distort the shape of a container of granular material without encountering any resistance.…

Soft Condensed Matter · Physics 2022-08-08 Yiqiu Zhao , Yuchen Zhao , Dong Wang , Hu Zheng , Bulbul Chakraborty , Joshua E. S. Socolar

We theoretically explore fluidization of epithelial tissues by active T1 neighbor exchanges. We show that the geometry of cell-cell junctions encodes important information about the local features of the energy landscape, which we support…

Soft Condensed Matter · Physics 2018-08-31 Matej Krajnc , Sabyasachi Dasgupta , Primož Ziherl , Jacques Prost

Vertex Models, as used to describe cellular tissue, have an energy controlled by deviations of each cell area and perimeter from target values. The constrained nonlinear relation between area and perimeter leads to new mechanical response.…

Soft Condensed Matter · Physics 2022-07-04 Arthur Hernandez , Michael F. Staddon , Mark J. Bowick , M. Cristina Marchetti , Michael Moshe