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This paper presents a soft earthworm robot that is capable of both efficient locomotion and obstacle avoidance. The robot is designed to replicate the unique locomotion mechanisms of earthworms, which enable them to move through narrow and…

Robotics · Computer Science 2024-02-06 Sean Even , Yasemin Ozkan-Aydin

Although part-based motion synthesis networks have been investigated to reduce the complexity of modeling heterogeneous human motions, their computational cost remains prohibitive in interactive applications. To this end, we propose a novel…

Graphics · Computer Science 2023-06-22 Shuaiying Hou , Hongyu Tao , Hujun Bao , Weiwei Xu

Domain-aware machine learning (ML) models have been increasingly adopted for accelerating small molecule therapeutic design in the recent years. These models have been enabled by significant advancement in state-of-the-art artificial…

Machine Learning · Computer Science 2021-02-12 Rajendra P. Joshi , Neeraj Kumar

The flow of motor proteins on a filamental track is modelled within the the framework of lattice driven diffusive systems. Motors, considered as hopping particles, perform a highly biased asymmetric exclusion process when bound to the…

Statistical Mechanics · Physics 2007-05-23 M. Ebrahim Fouladvand , Modjtaba Salehi , Mostafa Yadegari

As an emerging field, Automated Machine Learning (AutoML) aims to reduce or eliminate manual operations that require expertise in machine learning. In this paper, a graph-based architecture is employed to represent flexible combinations of…

Neural and Evolutionary Computing · Computer Science 2019-01-24 Fei Qi , Zhaohui Xia , Gaoyang Tang , Hang Yang , Yu Song , Guangrui Qian , Xiong An , Chunhuan Lin , Guangming Shi

Knotted molecules occur naturally and are designed by scientists to gain special biological and material properties. Understanding and utilizing knotting require efficient methods to recognize and generate knotted structures, which are…

Computational Physics · Physics 2025-01-23 Zhiyu Zhang , Yongjian Zhu , Liang Dai

With their unique combination of characteristics - an energy density almost 100 times that of human muscle, and a power density of 5.3 kW/kg, similar to a jet engine's output - Nylon artificial muscles stand out as particularly apt for…

Robotics · Computer Science 2023-10-05 Seyed Mo Mirvakili , Ehsan Haghighat , Douglas Sim

Conventional kinesin is a two-headed homodimeric motor protein, which is able to walk along microtubules processively by hydrolyzing ATP. Its neck linkers, which connect the two motor domains and can undergo a docking/undocking transition,…

Biomolecules · Quantitative Biology 2015-05-27 András Czövek , Gergely J Szöllősi , Imre Derényi

Control over molecular scale electrical properties within nano junctions is demonstrated, utilizing site-directed C60 targeting into protein macromolecules as a doping means. The protein molecules, self-assembled in a miniaturized…

Mesoscale and Nanoscale Physics · Physics 2011-12-13 Elad Mentovich , Bogdan Belgorodsky , Michael Gozin , Shachar Richter , Hagai Cohen

We present a model of an ATP-fueled molecular machine which push a polymer through a pore channel. The machine acts between two levels (working-waiting), and the working one remains active for a fixed time giving a constant force. The…

Soft Condensed Matter · Physics 2012-02-24 Alessandro Fiasconaro , Juan José Mazo , Fernando Falo

We argue that hardware modularity plays a key role in the convergence of Robotics and Artificial Intelligence (AI). We introduce a new approach for building robots that leads to more adaptable and capable machines. We present the concept of…

Robotics · Computer Science 2018-02-13 Víctor Mayoral , Risto Kojcev , Nora Etxezarreta , Alejandro Hernández , Irati Zamalloa

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various…

Emerging Technologies · Computer Science 2022-12-23 Sasitharan Balasubramaniam , Samitha Somathilaka , Sehee Sun , Adrian Ratwatte , Massimiliano Pierobon

Machine learning (ML)-guided directed evolution is a new paradigm for biological design that enables optimization of complex functions. ML methods use data to predict how sequence maps to function without requiring a detailed model of the…

Biomolecules · Quantitative Biology 2019-04-23 Kevin K. Yang , Zachary Wu , Frances H. Arnold

The increasing deployment of robots has significantly enhanced the automation levels across a wide and diverse range of industries. This paper investigates the automation challenges of laser-based dermatology procedures in the beauty…

Here we demonstrate a synthetic micro-engine, based on long-range controlled movement of colloidal particles, which is induced by a local catalytic reaction. The directed motion at long timescales was achieved by placing specially designed…

Statistical Mechanics · Physics 2008-07-16 Larysa Baraban , Christian Kreidler , Denys Makarov , Paul Leiderer , Artur Erbe

We propose a model for motor proteins based on a hierarchical Hamiltonian that we have previously introduced to describe protein folding. The proposed motor model has high efficiency and is consistent with a linear load-velocity response.…

Condensed Matter · Physics 2009-10-31 Alex Hansen , Mogens H. Jensen , Kim Sneppen , Giovanni Zocchi

A great advantage of legged robots is their ability to operate on particularly difficult and obstructed terrain, which demands dynamic, robust, and precise movements. The study of obstacle courses provides invaluable insights into the…

Robotics · Computer Science 2024-08-27 Maximilian Albracht , Shivesh Kumar , Shubham Vyas , Frank Kirchner

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

Statistical Mechanics · Physics 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

A geometric analysis of protein folding, which complements many of the models in the literature, is presented. We examine the process from unfolded strand to the point where the strand becomes self-interacting. A central question is how it…

Mathematical Physics · Physics 2008-09-13 Walter A. Simmons , Joel L. Weiner

A novel assay based on micropatterning and time-lapse microscopy has been developed for the study of nuclear migration dynamics in cultured mammalian cells. When cultured on 10-20 um wide adhesive stripes, the motility of C6 glioma and…

Cell Behavior · Quantitative Biology 2009-09-29 B. Szabo , Zs. Kornyei , J. Zach , D. Selmeczi , G. Csucs , A. Czirok , T. Vicsek