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We present the Julia package HomotopyContinuation.jl, which provides an algorithmic framework for solving polynomial systems by numerical homotopy continuation. We introduce the basic capabilities of the package and demonstrate the software…

Mathematical Software · Computer Science 2018-05-31 Paul Breiding , Sascha Timme

Despite recent advances in natural language processing, many statistical models for processing text perform extremely poorly under domain shift. Processing biomedical and clinical text is a critically important application area of natural…

Computation and Language · Computer Science 2021-03-24 Mark Neumann , Daniel King , Iz Beltagy , Waleed Ammar

Chemellia is an open-source framework for atomistic machine learning in the Julia programming language. The framework takes advantage of Julia's high speed as well as the ability to share and reuse code and interfaces through the paradigm…

Computational Engineering, Finance, and Science · Computer Science 2023-05-23 Anant Thazhemadam , Dhairya Gandhi , Venkatasubramanian Viswanathan , Rachel C. Kurchin

Analog Quantum Computers are promising tools for improving performance on applications such as modeling behavior of quantum materials, providing fast heuristic solutions to optimization problems, and simulating quantum systems. Due to the…

Quantum Physics · Physics 2024-07-31 Zachary Morrell , Marc Vuffray , Sidhant Misra , Carleton Coffrin

Computational elements in thermodynamics have become increasingly important in contemporary chemical-engineering research and practice. However, traditional thermodynamics instruction provides little exposure to computational…

Physics Education · Physics 2025-06-26 Luc Paoli , Pavan K. Inguva , Andrew J. Haslam , Pierre J. Walker

In this paper we present an introduction to the area of computability in dynamical systems. This is a fairly new field which has received quite some attention in recent years. One of the central questions in this area is if relevant…

Dynamical Systems · Mathematics 2023-11-08 Michael Burr , Christian Wolf

We introduce CBXPy and ConsensusBasedX.jl, Python and Julia implementations of consensus-based interacting particle systems (CBX), which generalise consensus-based optimization methods (CBO) for global, derivative-free optimisation. The…

Optimization and Control · Mathematics 2024-12-04 Rafael Bailo , Alethea Barbaro , Susana N. Gomes , Konstantin Riedl , Tim Roith , Claudia Totzeck , Urbain Vaes

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

The ability to represent scientific data and concepts visually is becoming increasingly important due to the unprecedented exponential growth of computational power during the present digital age. The data sets and simulations scientists in…

Instrumentation and Methods for Astrophysics · Physics 2009-11-18 Alyssa Goodman

ChatGPT, a recently developed product by openAI, is successfully leaving its mark as a multi-purpose natural language based chatbot. In this paper, we are more interested in analyzing its potential in the field of computational biology. A…

Artificial Intelligence · Computer Science 2023-12-05 Chowdhury Rafeed Rahman , Limsoon Wong

OutlierDetection.jl is an open-source ecosystem for outlier detection in Julia. It provides a range of high-performance outlier detection algorithms implemented directly in Julia. In contrast to previous packages, our ecosystem enables the…

Machine Learning · Computer Science 2022-11-10 David Muhr , Michael Affenzeller , Anthony D. Blaom

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Molecular biology and biochemistry interpret microscopic processes in the living world in terms of molecular structures and their interactions, which are quantum mechanical by their very nature. Whereas the theoretical foundations of these…

Quantum Physics · Physics 2023-07-07 Alberto Baiardi , Matthias Christandl , Markus Reiher

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

Large systems biology projects can encompass several workgroups often located in different countries. An overview about existing data standards in systems biology and the management, storage, exchange and integration of the generated data…

Databases · Computer Science 2009-12-15 Gerhard Mayer

Agent based modelling is a computational approach that aims to understand the behaviour of complex systems through simplified interactions of programmable objects in computer memory called agents. Agent based models (ABMs) are predominantly…

Multiagent Systems · Computer Science 2022-07-06 Renu Solanki , Monisha Khanna , Shailly Anand , Anita Gulati , Prateek Kumar , Munendra Kumar , Dushyant Kumar

Reproducibility of research is essential for science. However, in the way modern computational biology research is done, it is easy to lose track of small, but extremely critical, details. Key details, such as the specific version of a…

Increasingly sophisticated experiments, coupled with large-scale computational models, have the potential to systematically test biological hypotheses to drive our understanding of multicellular systems. In this short review, we explore key…

Quantitative Methods · Quantitative Biology 2019-10-28 Paul Macklin

One of the most compelling problems in science consists in understanding how living systems process information. After all, the way they process information defines their capacities to learning and adaptation. There is an increasing…

Adaptation and Self-Organizing Systems · Physics 2017-04-21 Carlos Eduardo Maldonado

Understanding large molecular networks consisting of entities such as genes, proteins or RNAs that interact in complex ways to drive the cellular machinery has been an active focus of systems biology. Computational approaches have played a…

Molecular Networks · Quantitative Biology 2013-04-23 Sriganesh Srihari , Mark A. Ragan