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Drosophila melanogaster, a small dipteran of African origin, represents one of the best-studied model organisms. Early work in this system has uniquely shed light on the basic principles of genetics and resulted in a versatile collection of…

Populations and Evolution · Quantitative Biology 2018-10-12 Annabelle Haudry , Stefan Laurent , Martin Kapun

The X chromosome is present as a single copy in the heterogametic sex, and this hemizygosity is expected to drive unusual patterns of evolution on the X relative to the autosomes. For example, the hemizgosity of the X may lead to a lower…

Populations and Evolution · Quantitative Biology 2015-03-20 Melek A. Kayserili , Dave T. Gerrard , Pavel Tomancak , Alex T. Kalinka

Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions. While there are some more complex genome rearrangements such as…

Genomics · Quantitative Biology 2015-04-07 Nikita Alexeev , Rustem Aidagulov , Max A. Alekseyev

Insertion of transposed elements within mammalian genes is thought to be an important contributor to mammalian evolution and speciation. Insertion of transposed elements into introns can lead to their activation as alternatively spliced…

Genomics · Quantitative Biology 2010-06-17 Noa Sela , Britta Mersch , Agnes Hotz-Wagenblatt , Gil Ast

The biological world, especially its majority microbial component, is strongly interacting and may be dominated by collective effects. In this review, we provide a brief introduction for statistical physicists of the way in which living…

Populations and Evolution · Quantitative Biology 2015-05-20 Nicholas Chia , Nigel Goldenfeld

Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale arrays of tandem repeats. Despite their importance, very…

Gene expression programming, a genotype/phenotype genetic algorithm (linear and ramified), is presented here for the first time as a new technique for the creation of computer programs. Gene expression programming uses character linear…

Artificial Intelligence · Computer Science 2007-05-23 Candida Ferreira

Natural selection at one site shapes patterns of genetic variation at linked sites. Quantifying the effects of 'linked selection' on levels of genetic diversity is key to making reliable inference about demography, building a null model in…

Populations and Evolution · Quantitative Biology 2016-08-30 Eyal Elyashiv , Shmuel Sattath , Tina T. Hu , Alon Strustovsky , Graham McVicker , Peter Andolfatto , Graham Coop , Guy Sella

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

A correlation between karyotype diversity and species richness was first observed in mammals in 1980, and subsequently confirmed after controlling for phylogenetic signal. The correlation was attributed to submicroscopic factors, presumably…

Populations and Evolution · Quantitative Biology 2025-11-18 John Herrick

Freshwater Unionid bivalves have recently faced ecological upheaval through pollution, barriers to dispersal, human harvesting, and changes in fish-host prevalence. Currently, over 70% of species are threatened, endangered or extinct. To…

Populations and Evolution · Quantitative Biology 2022-11-18 Rebekah L. Rogers , Stephanie L. Grizzard , Jeffrey T. Garner

Cryptic genetic sequences have attenuated effects on phenotypes. In the classic view, relaxed selection allows cryptic genetic diversity to build up across individuals in a population, providing alleles that may later contribute to…

Populations and Evolution · Quantitative Biology 2013-05-23 Etienne Rajon , Joanna Masel

Diversity-Generating Retroelements (DGRs) create rapid, targeted variation within specific genomic regions in phages and bacteria. They operate through stochastic retro-transcription of a template region (TR) into a variable region (VR),…

Populations and Evolution · Quantitative Biology 2026-02-19 Léo Régnier , Paul Rochette , Raphaël Laurenceau , David Bikard , Simona Cocco , Rémi Monasson

Evolution by Natural Selection is a process by which progeny inherit some properties from their progenitors with small variation. These properties are subject to Natural Selection and are called adaptive traits and carriers of the latter…

Analysis of PDEs · Mathematics 2024-01-29 Gonzalo Galiano , Yosef Cohen

How adaptive evolution to one environmental stress improves or suppresses adaptation to another is an important problem in evolutionary biology. For instance, in microbiology, the evolution of bacteria to be resistant to different…

Populations and Evolution · Quantitative Biology 2023-02-23 Takuya U. Sato , Chikara Furusawa , Kunihiko Kaneko

Transposable elements may acquire unrelated gene fragments into their sequences in a process called transduplication. Transduplication of protein-coding genes is common in plants, but is unknown of in animals. Here, we report that the…

Genomics · Quantitative Biology 2008-11-24 Noa Sela , Adi Stern , Wojciech Makalowski , Tal Pupko , Gil Ast

We have used the Monte Carlo based computer models to show that selection pressure could affect the distribution of recombination hotspots along the chromosome. Close to critical crossover rate, where genomes may switch between the…

Genomics · Quantitative Biology 2015-05-13 Jakub Kowalski , Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

The spatial dispersal of individuals is known to play an important role in the dynamics of populations, and is central to metapopulation theory. At the same time, local adaptation to environmental conditions creates a geographic mosaic of…

Populations and Evolution · Quantitative Biology 2017-09-25 Justin D. Yeakel , Jean P. Gibert , Peter A. H. Westley , Jonathan W. Moore

Various variants of the well known Covariance Matrix Adaptation Evolution Strategy (CMA-ES) have been proposed recently, which improve the empirical performance of the original algorithm by structural modifications. However, in practice it…

Neural and Evolutionary Computing · Computer Science 2018-08-20 Sander van Rijn , Hao Wang , Matthijs van Leeuwen , Thomas Bäck

The effects of the evolution force are observable in nature at all structural levels ranging from small molecular systems to conversely enormous biospheric systems. However, the evolution force and work associated with formation of…

Biological Physics · Physics 2021-03-19 Leroy K. Davis