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Machine learning methods for identifying molecular structures from tandem mass spectra (MS/MS) have advanced rapidly, yet current approaches still exhibit significant error rates. In high-stakes applications such as clinical metabolomics…

Machine Learning · Computer Science 2026-03-12 Mira Jürgens , Gaetan De Waele , Morteza Rakhshaninejad , Willem Waegeman

Technological and computational advances continuously drive forward the broad field of deep learning. In recent years, the derivation of quantities describing theuncertainty in the prediction - which naturally accompanies the modeling…

Machine Learning · Computer Science 2022-05-31 Christoph Koller , Göran Kauermann , Xiao Xiang Zhu

Expensive ultrasonic anemometers are usually required to measure wind speed accurately. The aim of this work is to overcome the loss of accuracy of a low cost hot-wire anemometer caused by the changes of air temperature, by means of a…

Majority voting and averaging are common approaches employed to resolve annotator disagreements and derive single ground truth labels from multiple annotations. However, annotators may systematically disagree with one another, often…

Computation and Language · Computer Science 2021-10-13 Aida Mostafazadeh Davani , Mark Díaz , Vinodkumar Prabhakaran

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Vanessa Gonzalez Duque , Leonhard Zirus , Yordanka Velikova , Nassir Navab , Diana Mateus

The success of Deep Neural Network (DNN) models significantly depends on the quality of provided annotations. In medical image segmentation, for example, having multiple expert annotations for each data point is common to minimize…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Asma Ahmed Hashmi , Aigerim Zhumabayeva , Nikita Kotelevskii , Artem Agafonov , Mohammad Yaqub , Maxim Panov , Martin Takáč

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

There are two major types of uncertainty one can model. Aleatoric uncertainty captures noise inherent in the observations. On the other hand, epistemic uncertainty accounts for uncertainty in the model -- uncertainty which can be explained…

Computer Vision and Pattern Recognition · Computer Science 2017-10-06 Alex Kendall , Yarin Gal

Although neural networks are powerful function approximators, the underlying modelling assumptions ultimately define the likelihood and thus the hypothesis class they are parameterizing. In classification, these assumptions are minimal as…

Machine Learning · Computer Science 2021-11-24 Maria R. Cervera , Rafael Dätwyler , Francesco D'Angelo , Hamza Keurti , Benjamin F. Grewe , Christian Henning

Graph Neural Networks (GNN) provide a powerful framework that elegantly integrates Graph theory with Machine learning for modeling and analysis of networked data. We consider the problem of quantifying the uncertainty in predictions of GNN…

Machine Learning · Computer Science 2022-05-23 Sai Munikoti , Deepesh Agarwal , Laya Das , Balasubramaniam Natarajan

This paper focuses on the unsupervised domain adaptation of transferring the knowledge from the source domain to the target domain in the context of semantic segmentation. Existing approaches usually regard the pseudo label as the ground…

Computer Vision and Pattern Recognition · Computer Science 2020-10-16 Zhedong Zheng , Yi Yang

Engineering simulations using boundary-value partial differential equations often implicitly assume that the uncertainty in the location of the boundary has a negligible impact on the output of the simulation. In this work, we develop a…

Tissues and Organs · Quantitative Biology 2024-06-11 S. Gerry Gralton , Farah Alkhatib , Ben Zwick , George Bourantas , Adam Wittek , Karol Miller

In machine learning, accurately predicting the probability that a specific input is correct is crucial for risk management. This process, known as uncertainty (or confidence) estimation, is particularly important in mission-critical…

Machine Learning · Computer Science 2023-01-12 Gabriella Chouraqui , Liron Cohen , Gil Einziger , Liel Leman

Jointly extracting entity pairs and their relations is challenging when working on distantly-supervised data with ambiguous or noisy labels. To mitigate such impact, we propose uncertainty-aware bootstrap learning, which is motivated by the…

Computation and Language · Computer Science 2023-06-12 Yufei Li , Xiao Yu , Yanchi Liu , Haifeng Chen , Cong Liu

Statistical models incorporating change points are common in practice, especially in the area of biomedicine. This approach is appealing in that a specific parameter is introduced to account for the abrupt change in the response variable…

Statistics Theory · Mathematics 2008-12-18 Hongling Zhou , Kung-Yee Liang

Traditionally, most of the existing attribute learning methods are trained based on the consensus of annotations aggregated from a limited number of annotators. However, the consensus might fail in settings, especially when a wide spectrum…

Machine Learning · Computer Science 2019-06-19 Zhiyong Yang , Qianqian Xu , Xiaochun Cao , Qingming Huang

Lesions or organ boundaries visible through medical imaging data are often ambiguous, thus resulting in significant variations in multi-reader delineations, i.e., the source of aleatoric uncertainty. In particular, quantifying the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Xiaofeng Liu , Fangxu Xing , Thibault Marin , Georges El Fakhri , Jonghye Woo

For the purposes of computational dialectology or other geographically bound text analysis tasks, texts must be annotated with their or their authors' location. Many texts are locatable through explicit labels but most have no explicit…

Computation and Language · Computer Science 2016-12-21 Max Berggren , Jussi Karlgren , Robert Östling , Mikael Parkvall

Thousands of scanned historical topographic maps contain valuable information covering long periods of time, such as how the hydrography of a region has changed over time. Efficiently unlocking the information in these maps requires…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Weiwei Duan , Yao-Yi Chiang , Stefan Leyk , Johannes H. Uhl , Craig A. Knoblock