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Mechanical properties of tissue provide valuable information for identifying lesions. One approach to obtain quantitative estimates of elastic properties is shear wave elastography with optical coherence elastography (OCE). However, given…

Image and Video Processing · Electrical Eng. & Systems 2020-04-30 Maximilian Neidhardt , Marcel Bengs , Sarah Latus , Matthias Schlüter , Thore Saathoff , Alexander Schlaefer

Purpose. Needle placement is a challenging problem for applications such as biopsy or brachytherapy. Tip force sensing can provide valuable feedback for needle navigation inside the tissue. For this purpose, fiber-optical sensors can be…

Image and Video Processing · Electrical Eng. & Systems 2020-08-07 M. Gromniak , N. Gessert , T. Saathoff , A. Schlaefer

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Needle positioning is essential for various medical applications such as epidural anaesthesia. Physicians rely on their instincts while navigating the needle in epidural spaces. Thereby, identifying the tissue structures may be helpful to…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Debayan Bhattacharya , Sarah Latus , Finn Behrendt , Florin Thimm , Dennis Eggert , Christian Betz , Alexander Schlaefer

Robot-assisted surgery has advantages compared to conventional laparoscopic procedures, e.g., precise movement of the surgical instruments, improved dexterity, and high-resolution visualization of the surgical field. However, mechanical…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Maximilian Neidhardt , Robin Mieling , Sarah Latus , Martin Fischer , Tobias Maurer , Alexander Schlaefer

We demonstrate that a simple, unscanned polarization-sensitive optical coherence tomography needle probe can be used to perform layer identification in biological tissues. Broadband light from a laser centered at 1310 nm was sent through a…

Medical Physics · Physics 2023-10-06 Danielle J. Harper , Yongjoo Kim , Alejandra Gómez-Ramírez , Benjamin J. Vakoc

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Mayank Goswami

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Optical coherence elastography (OCE) is a powerful non-invasive imaging technique for high-resolution assessment of tissue elasticity and viscoelasticity. Accurate characterization of viscoelastic properties requires estimating shear wave…

To explore the clinical validity of elastic deformation of optical coherence tomography (OCT) images for data augmentation in the development of deep-learning model for detection of diabetic macular edema (DME).

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Daniel Bar-David , Laura Bar-David , Yinon Shapira , Rina Leibu , Dalia Dori , Ronit Schneor , Anath Fischer , Shiri Soudry

This paper proposes a smart handheld textural sensing medical device with complementary Machine Learning (ML) algorithms to enable on-site Colorectal Cancer (CRC) polyp diagnosis and pathology of excised tumors. The proposed unique handheld…

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

We demonstrate a deep-learning-based scatterer density estimator (SDE) that processes local speckle patterns of optical coherence tomography (OCT) images and estimates the scatterer density behind each speckle pattern. The SDE is trained…

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

Purpose. Precise placement of needles is a challenge in a number of clinical applications such as brachytherapy or biopsy. Forces acting at the needle cause tissue deformation and needle deflection which in turn may lead to misplacement or…

Displacement estimation in optical coherence tomography (OCT) imaging is relevant for several potential applications, e.g. for optical coherence elastography (OCE) for corneal biomechanical characterization. Larger displacements may be…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Hossein Khodadadi , Orcun Goksel , Sabine Kling

Optical coherence tomography (OCT) is a non-invasive volumetric imaging modality with high spatial and temporal resolution. For imaging larger tissue structures, OCT probes need to be moved to scan the respective area. For handheld…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Suresh Guttikonda , Maximilian Neidhardt , Vidas Raudonis , Alexander Schlaefer

Lens tension is essential for accommodative vision but remains difficult to measure with precision. Here, we present an optical coherence elastography (OCE) technique that quantifies both tension and elastic modulus in the lens capsule and…

Applied Physics · Physics 2025-12-29 Xu Feng , Guo-yang Li , Yuxuan Jiang , Owen Shortt-Nguyen , Seok-Hyun Yun

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Traveling-wave optical coherence elastography (OCE) is a promising technique to measure the stiffness of biological tissues. While OCE has been applied to relatively homogeneous samples, tissues with significantly varying elasticity through…

Medical Physics · Physics 2022-01-31 Xu Feng , Guo-Yang Li , Antoine Ramier , Amira M. Eltony , Seok-Hyun Yun
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