Related papers: Mass vaccination in a roaring pandemic
The introduction of the rotavirus vaccine in the United Kingdom (UK) in 2013 led to a noticeable decline in laboratory reports in subsequent years. To assess the impact of vaccination on rotavirus transmissibility we calibrated a stochastic…
Knowledge of the protection afforded by vaccines might, in some circumstances, modify a vaccinated individual's behaviour, potentially increasing exposure to pathogens and hindering effectiveness. Although vaccine studies typically do not…
By the end of 2020, a year since the first cases of infection by the Covid-19 virus have been reported, there is a light at the end of the tunnel. Several pharmaceutical companies made significant progress in developing effective vaccines…
Population heterogeneity, especially in individuals' contact networks, plays an important role in transmission dynamics of infectious diseases. For vaccine-preventable diseases, outstanding issues like vaccine hesitancy and availability of…
In this work we analyze the evolution of voluntary vaccination in networked populations by entangling the spreading dynamics of an influenza-like disease with an evolutionary framework taking place at the end of each influenza season so…
Voluntary vaccination is effective to prevent infectious diseases from spreading. Both vaccination behavior and cognition of the vaccination risk play important roles in individual vaccination decision making. However, it is not clear how…
Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…
The spreading of infectious diseases with and without immunization of individuals can be modeled by stochastic processes that exhibit a transition between an active phase of epidemic spreading and an absorbing phase, where the disease dies…
We investigate stochastic extinction in an epidemic model and the impact of random vaccinations in large populations. We show that, in the absence of vaccinations, the effective entropic barrier for extinction displays scaling with the…
Purpose: Only few companies were able to produce vaccine again COVID-19. Thus, one producer supplied it to many countries. The distribution was not effective. Some countries overstocked the vaccine while other countries were not able to buy…
The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of genetic clades. New variants show intrinsic changes, notably increased transmissibility, as well as antigenic changes that reduce the cross-immunity…
The response of the immune system to different vaccination patterns is studied with a simple model. It is argued that the history and characteristics of the pattern defines very different secondary immune responses in the case of infection.…
Most vaccines require multiple doses, the first to induce recognition and antibody production and subsequent doses to boost the primary response and achieve optimal protection. We show that properly prioritizing the administration of first…
The potential waning of the vaccination immunity to COVID-19 could pose threats to public health, as it is tenable that the timing of such waning would synchronize with the near-complete restoration of normalcy. Should also testing be…
Voluntary vaccination is essential to protect oneself from infection and suppress the spread of infectious diseases. Voluntary vaccination behavior is influenced by factors such as age and interaction patterns. Differences in health…
Optimal strategies for epidemic containment are focused on dismantling the contact network through effective immunization with minimal costs. However, network fragmentation is seldom accessible in practice and may present extreme side…
In order to slow the spread of the CoViD-19 pandemic, governments around the world have enacted a wide set of policies limiting the transmission of the disease. Initially, these focused on non-pharmaceutical interventions; more recently,…
Heterogeneity of population is a key factor in modeling the transmission of disease among the population and has huge impact on the outcome of the transmission. In order to investigate the decision making process in the heterogeneous mixing…
Polarization of opinions about vaccination can have a negative impact on pandemic control. In this work we quantify this negative impact for the transmission of COVID-19, using an agent based simulation in an heterogeneous population with…
Seasonal influenza is a significant public health concern in the United States and globally. While influenza vaccines are the single most effective intervention to reduce influenza morbidity and mortality, there is considerable debate…