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Autism Spectrum Disorder (ASD) represents a multifaceted neurodevelopmental condition marked by difficulties in social interaction, communication impediments, and repetitive behaviors. Despite progress in understanding ASD, its diagnosis…

Artificial Intelligence · Computer Science 2024-07-15 Hossein Mohammadi Rouzbahani , Hadis Karimipour

The insufficient supervision limit the performance of the deep supervised models for brain disease diagnosis. It is important to develop a learning framework that can capture more information in limited data and insufficient supervision. To…

Neurons and Cognition · Quantitative Biology 2024-10-10 Wenjing Gao , Yuanyuan Yang , Jianrui Wei , Xuntao Yin , Xinhan Di

Machine learning (ML) has advanced quickly, particularly throughout the area of health care. The diagnosis of neurodevelopment problems using ML is a very important area of healthcare. Autism spectrum disorder (ASD) is one of the…

Machine Learning · Computer Science 2024-04-04 Trapti Shrivastava , Harshal Chaudhari , Vrijendra Singh

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two…

Machine Learning · Statistics 2016-12-04 Rushil Anirudh , Jayaraman J. Thiagarajan , Irene Kim , Wolfgang Polonik

Autism spectrum disorder (ASD) can be defined as a neurodevelopmental disorder that affects how children interact, communicate and socialize with others. This disorder can occur in a broad spectrum of symptoms, with varying effects and…

Machine Learning · Computer Science 2021-10-08 Vikram Ramesh , Rida Assaf

Understanding the complex neural activity dynamics is crucial for the development of the field of neuroscience. Although current functional MRI classification approaches tend to be based on static functional connectivity or cannot capture…

Machine Learning · Computer Science 2025-08-20 Amirali Arbab , Zeinab Davarani , Mehran Safayani

Autism spectrum disorders (ASDs) are developmental conditions characterized by restricted interests and difficulties in communication. The complexity of ASD has resulted in a deficiency of objective diagnostic biomarkers. Deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-03-28 Xinyuan Zheng , Orren Ravid , Robert A. J. Barry , Yoojean Kim , Qian Wang , Young-geun Kim , Xi Zhu , Xiaofu He

Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

Using predictive models to identify patterns that can act as biomarkers for different neuropathoglogical conditions is becoming highly prevalent. In this paper, we consider the problem of Autism Spectrum Disorder (ASD) classification where…

Machine Learning · Statistics 2018-10-31 Rushil Anirudh , Jayaraman J. Thiagarajan

Autism spectrum disorder(ASD) is a lifelong neurodevelopmental condition that affects social communication and behavior. Investigating functional magnetic resonance imaging (fMRI)-based brain functional connectome can aid in the…

Neurons and Cognition · Quantitative Biology 2023-07-21 Anushree Bannadabhavi , Soojin Lee , Wenlong Deng , Xiaoxiao Li

Eye movements have been widely investigated to study the atypical visual attention in Autism Spectrum Disorder (ASD). The majority of these studies have been focused on limited eye movement features by statistical comparisons between ASD…

Image and Video Processing · Electrical Eng. & Systems 2019-11-27 Jin Xie , Longfei Wang , Paula Webster , Yang Yao , Jiayao Sun , Shuo Wang , Huihui Zhou

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Diagnosing autism spectrum disorder (ASD) by identifying abnormal speech patterns from examiner-patient dialogues presents significant challenges due to the subtle and diverse manifestations of speech-related symptoms in affected…

Sound · Computer Science 2024-05-09 Chuanbo Hu , Jacob Thrasher , Wenqi Li , Mindi Ruan , Xiangxu Yu , Lynn K Paul , Shuo Wang , Xin Li

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

Neurons and Cognition · Quantitative Biology 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

The multifactorial etiology of autism spectrum disorder (ASD) suggests that its study would benefit greatly from multimodal approaches that combine data from widely varying platforms, e.g., neuroimaging, genetics, and clinical…

Quantitative Methods · Quantitative Biology 2023-08-11 Nicha C. Dvornek , Catherine Sullivan , James S. Duncan , Abha R. Gupta

Attention Deficit Hyperactive Disorder (ADHD) is a common behavioral problem affecting children. In this work, we investigate the automatic classification of ADHD subjects using the resting state Functional Magnetic Resonance Imaging (fMRI)…

Neurons and Cognition · Quantitative Biology 2023-06-16 Soumyabrata Dey , Ravishankar Rao , Mubarak Shah

Brain network topology, derived from functional magnetic resonance imaging (fMRI), holds promise for improving Alzheimer's disease (AD) diagnosis. Current methods primarily focus on lower-order topological features, often overlooking the…

Geometric Topology · Mathematics 2025-09-19 Dengyi Zhao , Shanyong Li , Yunping Wang , Chenfei Wang , Zhiheng Zhou , Guiying Yan , Xingqin Qi

Autism spectrum disorder (ASD) represents a neurodevelopmental condition characterized by difficulties in expressing emotions and communication, particularly during early childhood. Understanding the affective state of children at an early…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Aura Loredana Dan

Graphs are widely used as a natural framework that captures interactions between individual elements represented as nodes in a graph. In medical applications, specifically, nodes can represent individuals within a potentially large…