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Recently, machine learning methods have been used to propose molecules with desired properties, which is especially useful for exploring large chemical spaces efficiently. However, these methods rely on fully labelled training data, and are…

Chemical Physics · Physics 2023-08-16 Jonathan P. Mailoa , Xin Li , Jiezhong Qiu , Shengyu Zhang

Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Machine Learning · Computer Science 2026-04-08 Kevin Zhang , Yixin Wang

Recent advances in generative artificial intelligence have had a significant impact on diverse domains spanning computer vision, natural language processing, and drug discovery. This work extends the reach of generative models into physical…

Machine Learning · Computer Science 2024-10-22 Christian Jacobsen , Yilin Zhuang , Karthik Duraisamy

Text-to-image diffusion models have demonstrated tremendous success in synthesizing visually stunning images given textual instructions. Despite remarkable progress in creating high-fidelity visuals, text-to-image models can still struggle…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Taewook Kim , Ze Wang , Zhengyuan Yang , Jiang Wang , Lijuan Wang , Zicheng Liu , Qiang Qiu

Class-conditional generative models are crucial tools for data generation from user-specified class labels. Existing approaches for class-conditional generative models require nontrivial modifications of backbone generative architectures to…

Machine Learning · Computer Science 2023-05-09 Enmao Diao , Jie Ding , Vahid Tarokh

We present a new perspective of achieving image synthesis by viewing this task as a visual token generation problem. Different from existing paradigms that directly synthesize a full image from a single input (e.g., a latent code), the new…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Yanhong Zeng , Huan Yang , Hongyang Chao , Jianbo Wang , Jianlong Fu

Large transformer-based language models (LMs) trained on huge text corpora have shown unparalleled generation capabilities. However, controlling attributes of the generated language (e.g. switching topic or sentiment) is difficult without…

Computation and Language · Computer Science 2020-03-04 Sumanth Dathathri , Andrea Madotto , Janice Lan , Jane Hung , Eric Frank , Piero Molino , Jason Yosinski , Rosanne Liu

Disentangled representations can be useful in many downstream tasks, help to make deep learning models more interpretable, and allow for control over features of synthetically generated images that can be useful in training other models…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Aadhithya Sankar , Matthias Keicher , Rami Eisawy , Abhijeet Parida , Franz Pfister , Seong Tae Kim , Nassir Navab

Despite recent success in conditional image synthesis, prevalent input conditions such as semantics and edges are not clear enough to express `Linear (Ridges)' and `Planar (Scale)' representations. To address this problem, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-16 Gunhee Lee , Jonghwa Yim , Chanran Kim , Minjae Kim

Recent text-to-image diffusion models are able to learn and synthesize images containing novel, personalized concepts (e.g., their own pets or specific items) with just a few examples for training. This paper tackles two interconnected…

Computer Vision and Pattern Recognition · Computer Science 2024-02-26 Chun-Hsiao Yeh , Ta-Ying Cheng , He-Yen Hsieh , Chuan-En Lin , Yi Ma , Andrew Markham , Niki Trigoni , H. T. Kung , Yubei Chen

Recently introduced generative adversarial network (GAN) has been shown numerous promising results to generate realistic samples. The essential task of GAN is to control the features of samples generated from a random distribution. While…

Machine Learning · Computer Science 2019-04-02 Minhyeok Lee , Junhee Seok

Synthetic medical image generation has a huge potential for improving healthcare through many applications, from data augmentation for training machine learning systems to preserving patient privacy. Conditional Adversarial Generative…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Mohammad Havaei , Ximeng Mao , Yiping Wang , Qicheng Lao

This paper adapts a StyleGAN model for speech generation with minimal or no conditioning on text. StyleGAN is a multi-scale convolutional GAN capable of hierarchically capturing data structure and latent variation on multiple spatial (or…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-17 Kasperi Palkama , Lauri Juvela , Alexander Ilin

Generating molecules that satisfy precise numeric constraints over multiple physicochemical properties is critical and challenging. Although large language models (LLMs) are expressive, they struggle with precise multi-objective control and…

Artificial Intelligence · Computer Science 2026-01-19 Yizhan Li , Florence Cloutier , Sifan Wu , Ali Parviz , Boris Knyazev , Yan Zhang , Glen Berseth , Bang Liu

Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…

Quantitative Methods · Quantitative Biology 2025-10-13 Berker Demirel , Marco Fumero , Theofanis Karaletsos , Francesco Locatello

This work addresses the challenging domain adaptation setting in which knowledge from the labelled source domain dataset is available only from the pretrained black-box segmentation model. The pretrained model's predictions for the target…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Gabriel Tjio , Ping Liu , Yawei Luo , Chee Keong Kwoh , Joey Zhou Tianyi

Synthesizing high resolution photorealistic images has been a long-standing challenge in machine learning. In this paper we introduce new methods for the improved training of generative adversarial networks (GANs) for image synthesis. We…

Machine Learning · Statistics 2017-07-24 Augustus Odena , Christopher Olah , Jonathon Shlens

We present RoboGen, a generative robotic agent that automatically learns diverse robotic skills at scale via generative simulation. RoboGen leverages the latest advancements in foundation and generative models. Instead of directly using or…

In recent years, deep learning has been successfully adopted in a wide range of applications related to electronic health records (EHRs) such as representation learning and clinical event prediction. However, due to privacy constraints,…

Machine Learning · Computer Science 2023-09-04 Chang Lu , Chandan K. Reddy , Ping Wang , Dong Nie , Yue Ning

Programmatic Weak Supervision (PWS) and generative models serve as crucial tools that enable researchers to maximize the utility of existing datasets without resorting to laborious data gathering and manual annotation processes. PWS uses…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Kumar Shubham , Pranav Sastry , Prathosh AP
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