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Contrastive learning is a recent promising approach in unsupervised representation learning where a feature representation of data is learned by solving a pseudo classification problem from unlabelled data. However, it is not…

Machine Learning · Computer Science 2022-08-10 Hiroaki Sasaki , Takashi Takenouchi

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Identifying molecules from mass spectrometry (MS) data remains a fundamental challenge due to the semantic gap between physical spectral peaks and underlying chemical structures. Existing deep learning approaches often treat spectral…

Machine Learning · Computer Science 2026-02-03 Seunghyun Yoo , Sanghong Kim , Namkyung Yoon , Hwangnam Kim

Capturing molecular knowledge with representation learning approaches holds significant potential in vast scientific fields such as chemistry and life science. An effective and generalizable molecular representation is expected to capture…

Machine Learning · Computer Science 2024-06-17 Yizhen Luo , Kai Yang , Massimo Hong , Xing Yi Liu , Zikun Nie , Hao Zhou , Zaiqing Nie

We seek to automate the design of molecules based on specific chemical properties. Our primary contributions are a simpler method for generating SMILES strings guaranteed to be chemically valid, using a combination of a new context-free…

Machine Learning · Computer Science 2018-11-29 Egor Kraev

Molecular property prediction is a fundamental task in computational chemistry with critical applications in drug discovery and materials science. While recent works have explored Large Language Models (LLMs) for this task, they primarily…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Deepan Adak , Yogesh Singh Rawat , Shruti Vyas

The field of chemistry and Artificial Intelligence (AI) intersection is an area of active research that aims to accelerate scientific discovery. The integration of large language models (LLMs) with scientific modalities has shown…

Computation and Language · Computer Science 2024-07-16 Dimitris Gkoumas

In this paper, we propose a new progressive pre-training method for image understanding tasks which leverages RGB-D datasets. The method utilizes Multi-Modal Contrastive Masked Autoencoder and Denoising techniques. Our proposed approach…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Muhammad Abdullah Jamal , Omid Mohareri

Recent advancements in Multimodal Large Language Models (MLLMs) have revolutionized the field of vision-language understanding by integrating visual perception capabilities into Large Language Models (LLMs). The prevailing trend in this…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Sirnam Swetha , Jinyu Yang , Tal Neiman , Mamshad Nayeem Rizve , Son Tran , Benjamin Yao , Trishul Chilimbi , Mubarak Shah

Vision-language models pre-trained on large scale of unlabeled biomedical images and associated reports learn generalizable semantic representations. These multi-modal representations can benefit various downstream tasks in the biomedical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xinliu Zhong , Kayhan Batmanghelich , Li Sun

Face analysis tasks have a wide range of applications, but the universal facial representation has only been explored in a few works. In this paper, we explore high-performance pre-training methods to boost the face analysis tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Yue Wang , Jinlong Peng , Jiangning Zhang , Ran Yi , Liang Liu , Yabiao Wang , Chengjie Wang

Most spoken language understanding systems use a pipeline approach composed of an automatic speech recognition interface and a natural language understanding module. This approach forces hard decisions when converting continuous inputs into…

Computation and Language · Computer Science 2023-10-18 Quentin Meeus , Marie-Francine Moens , Hugo Van hamme

Contrastive learning has become pivotal in unsupervised representation learning, with frameworks like Momentum Contrast (MoCo) effectively utilizing large negative sample sets to extract discriminative features. However, traditional…

Machine Learning · Computer Science 2025-01-29 Duy Hoang , Huy Ngo , Khoi Pham , Tri Nguyen , Gia Bao , Huy Phan

Image-text multimodal representation learning aligns data across modalities and enables important medical applications, e.g., image classification, visual grounding, and cross-modal retrieval. In this work, we establish a connection between…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Peiqi Wang , William M. Wells , Seth Berkowitz , Steven Horng , Polina Golland

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Multimodal representation learning, exemplified by multimodal contrastive learning (MMCL) using image-text pairs, aims to learn powerful representations by aligning cues across modalities. This approach relies on the core assumption that…

Machine Learning · Computer Science 2025-09-29 Yichao Cai , Yuhang Liu , Erdun Gao , Tianjiao Jiang , Zhen Zhang , Anton van den Hengel , Javen Qinfeng Shi

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches…

Machine Learning · Computer Science 2026-03-24 Long Xu , Junping Guo , Jianbo Zhao , Jianbo Lu , Yuzhong Peng

Recent advances in molecular representation integrates molecular topological and visual modalities, opening new avenues for precise Molecular Relational Learning (MRL). Existing MRL methods focus on intra-domain modeling, and their inherent…

Machine Learning · Computer Science 2026-05-25 Peiliang Zhang , Jingling Yuan , Shiqing Wu , Mengqing Hu , Chao Che , Yongjun Zhu , Lin Li

Recent multi-modal contrastive learning models have demonstrated the ability to learn an embedding space suitable for building strong vision classifiers, by leveraging the rich information in large-scale image-caption datasets. Our work…

Machine Learning · Computer Science 2023-02-09 Yuhui Zhang , Jeff Z. HaoChen , Shih-Cheng Huang , Kuan-Chieh Wang , James Zou , Serena Yeung

In the field of chemistry, the objective is to create novel molecules with desired properties, facilitating accurate property predictions for applications such as material design and drug screening. However, existing graph deep learning…

Machine Learning · Computer Science 2024-08-28 Sakhinana Sagar Srinivas , Venkataramana Runkana