Related papers: Partial-Field Illumination Ophthalmoscope: improvi…
The evaluation and monitoring of cells health in the human retina is crucial and follow time course of retinal diseases, detect lesions before irreversible visual loss and to evaluate treatment effects. Towards this goal, a major challenge…
A resolution-enhanced dark-field microscope by structured light illumination is proposed to improve resolution and contrast. A set of phase-shifted fringes are projected to the sample plane at large angle to capture modulated dark-field…
The health of cells found in the inner retinal layers of the human eye is crucial to understand the onset of diseases of the retina such as macular degeneration and retinopathy. A challenge is to periodically image these cells in human eyes…
Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…
A comprehensive assessment of retinal health demands reliable and precise methods to measure localized blood perfusion. Despite considerable advancements in imaging techniques, such as indocyanine green and fluorescein angiography, along…
Structured illumination can reject out-of-focus signal from a sample, enabling high-speed and high-contrast imaging over large areas with widefield detection optics. Currently, this optical-sectioning technique is limited by image…
Adaptive optical correction is an efficient technique to obtain high-resolution images of the retinal surface. A main limitation of adaptive optical correction, however, is the small size of the corrected image. For medical purposes it is…
An image-based technique for measuring the complex field in the pupil of an imaging system is presented. Two point source images, one with a small modification introduced in the pupil, are combined using a simple and non-iterative…
Traditional optical imaging faces an unavoidable trade-off between resolution and depth of field (DOF). To increase resolution, high numerical apertures (NA) are needed, but the associated large angular uncertainty results in a limited…
We present an overview of the performances of a plenoptic microscope which combines the high sensitivity of a laser optical feedback imaging setup , the high resolution of optical synthetic aperture and a shot noise limited signal to noise…
The contrast of an image can be degraded by the presence of background light and sensor noise. To overcome this degradation, quantum illumination protocols have been theorised (Science 321 (2008), Physics Review Letters 101 (2008)) that…
Interferometric-based microscopies stand as powerful label-free approaches for monitoring and characterising chemical reactions and heterogeneous nanoparticle systems in real time with single particle sensitivity. Nevertheless, coherent…
This paper proposes a novel image contrast enhancement method based on both a noise aware shadow-up function and Retinex (retina and cortex) decomposition. Under low light conditions, images taken by digital cameras have low contrast in…
Polarization-resolved near-infrared imaging adds a useful optical contrast mechanism to eye tracking by measuring the polarization state of light reflected by ocular tissues in addition to its intensity. In this paper we demonstrate how…
Ultra-Wide-Field (UWF) retinal imaging has revolutionized retinal diagnostics by providing a comprehensive view of the retina. However, it often suffers from quality-degrading factors such as blurring and uneven illumination, which obscure…
Non-invasive imaging plays a crucial role in diagnosing and studying eye diseases. However, existing photoacoustic ophthalmoscopy (PAOM) techniques in mice have limitations due to handling restrictions, suboptimal optical properties,…
Low-light image enhancement task is essential yet challenging as it is ill-posed intrinsically. Previous arts mainly focus on the low-light images captured in the visible spectrum using pixel-wise loss, which limits the capacity of…
We develop a framework for rendering photographic images, taking into account display limitations, so as to optimize perceptual similarity between the rendered image and the original scene. We formulate this as a constrained optimization…
This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…
Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…