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Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Spatial resolution of most imaging devices is fundamentally restricted by diffraction. This limitation is manifested in the loss of high spatial frequency information contained in evanescent waves. As a result, conventional far-field optics…

Optics · Physics 2010-03-16 Leonid Alekseyev , Evgenii Narimanov , Jacob Khurgin

Angular speckle correlations known as the 'memory-effect' have recently been exploited for non-invasive imaging through scattering layers. Here, we show how the imaging information obtained from speckle correlations can be used as a…

Optics · Physics 2019-01-30 Galya Stern , Ori Katz

We introduce a practical digital holographic method capable of imaging through a diffusive or scattering medium. The method relies on statistical averaging from a rotating ground glass diffuser to negate the adverse effects caused by…

We demonstrate a high-speed method to image objects through a thin scattering medium and around a corner. The method employs a reference object of known shape to retrieve the speckle-like point spread function of the scatterer. We extract…

Optical imaging through complex scattering media is one of the major technical challenges with important applications in many research fields, ranging from biomedical imaging, astronomical telescopy, and spatially multiplex optical…

Scattering can rapidly degrade our ability to form an optical image, to the point where only speckle-like patterns can be measured. Truly non-invasive imaging through a strongly scattering obstacle is difficult, and usually reliant on a…

Optics · Physics 2022-10-26 Y. Jauregui-Sánchez , Harry Penketh , Jacopo Bertolotti

Light passing through scattering media will be strongly scattered and diffused into complex speckle pattern, which however contains almost all the spatial information and color information of the objects. Although various technologies have…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Lei Zhu , Yuxiang Wu , Jietao Liu , Tengfei Wu , Lixian Liu , Xiaopeng Shao

Recovering the physical attributes of an object's appearance from its images captured under an unknown illumination is challenging yet essential for photo-realistic rendering. Recent approaches adopt the emerging implicit scene…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Youjia Zhang , Teng Xu , Junqing Yu , Yuteng Ye , Junle Wang , Yanqing Jing , Jingyi Yu , Wei Yang

Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most…

Optics · Physics 2014-03-04 T. Chaigne , O. Katz , A. C. Boccara , M. Fink , E. Bossy , S. Gigan

Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…

Optics · Physics 2024-01-23 Dror Aizik , Anat Levin

The ability to spatially and temporally map nanoscale environments in situ over extended timescales would be transformative for biology, biomedicine, and bioengineering. All nanometer objects, from nanoparticles down to single proteins,…

Optics · Physics 2023-10-04 Guangjie Cui , Do Young Kim , Di Zu , Guanbo Chai , Somin Eunice Lee

Just as turbulence in the Earth's atmosphere can severely limit the angular resolution of optical telescopes, turbulence in the ionized interstellar medium fundamentally limits the resolution of radio telescopes. We present a scattering…

Instrumentation and Methods for Astrophysics · Physics 2016-12-14 Michael D. Johnson

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. Recently, it was demonstrated that it is possible to surpass the acoustic diffraction limit by analyzing fluctuations in a set of…

By switching fluorophores on and off in either a deterministic or a stochastic manner, superresolution microscopy has enabled the imaging of biological structures at resolutions well beyond the diffraction limit. Superresolution optical…

Object-motion-based speckle correlation can recover hidden objects from any inhomogeneous medium, which takes advantage of the inherent connection that the cross-correlation between speckle patterns can reflect the autocorrelation of…

Optics · Physics 2023-12-01 Zhao Wang , Rui Ma , Mingzhu She , Anda Shi , Weili Zhang

We exploit memory effect speckle correlations for the imaging of incoherent linear (single-photon) fluorescent sources behind scattering tissue. While memory effect-based imaging techniques have been heavily studied in the past, for thick…

Surface molecules, distributed in diverse patterns and clusters on cell membranes, influence vital functions of living cells. It is therefore important to understand their molecular surface organisation under different physiological and…

To overcome the limit of diffraction while achieving the superresolution technique, solid immersion lenses are the key optical elements for data storage and nanophotonics applications. Recent demonstrations have shown how different…

Optics · Physics 2026-02-24 Subhankar Roy , Jianping Hu , M Ummal Momeen

Sensing and manipulating targets hidden under scattering media are universal problems that take place in applications ranging from deep-tissue optical imaging to laser surgery. A major issue in these applications is the shallow light…

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