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Bayesian Non-negative Matrix Factorization (NMF) is a promising approach for understanding uncertainty and structure in matrix data. However, a large volume of applied work optimizes traditional non-Bayesian NMF objectives that fail to…

Machine Learning · Statistics 2018-03-19 M. Arjumand Masood , Finale Doshi-Velez

The drug discovery and development process is a long and expensive one, costing over 1 billion USD on average per drug and taking 10-15 years. To reduce the high levels of attrition throughout the process, there has been a growing interest…

Quantitative Methods · Quantitative Biology 2022-08-22 Cheng Ye , Rowan Swiers , Stephen Bonner , Ian Barrett

Nonnegative matrix factorization (NMF) is a linear dimensionality reduction technique for analyzing nonnegative data. A key aspect of NMF is the choice of the objective function that depends on the noise model (or statistics of the noise)…

Machine Learning · Computer Science 2021-02-10 Nicolas Gillis , Le Thi Khanh Hien , Valentin Leplat , Vincent Y. F. Tan

We introduce negative binomial matrix factorization (NBMF), a matrix factorization technique specially designed for analyzing over-dispersed count data. It can be viewed as an extension of Poisson matrix factorization (PF) perturbed by a…

Machine Learning · Computer Science 2018-01-08 Olivier Gouvert , Thomas Oberlin , Cédric Févotte

Missing link prediction is a method for network analysis, with applications in recommender systems, biology, social sciences, cybersecurity, information retrieval, and Artificial Intelligence (AI) reasoning in Knowledge Graphs. Missing link…

Machine Learning · Computer Science 2025-03-07 Ryan Barron , Maksim E. Eren , Duc P. Truong , Cynthia Matuszek , James Wendelberger , Mary F. Dorn , Boian Alexandrov

The understanding of the type of inhibitory interaction plays an important role in drug design. Therefore, researchers are interested to know whether a drug has competitive or non-competitive interaction to particular protein targets.…

Data with underlying nonlinear structure are collected across numerous application domains, necessitating new data processing and analysis methods adapted to nonlinear domain structure. Riemannanian manifolds present a rich environment in…

Numerical Analysis · Mathematics 2025-02-24 Joyce Chew , Willem Diepeveen , Deanna Needell

Linear dimensionality reduction techniques are powerful tools for image analysis as they allow the identification of important features in a data set. In particular, nonnegative matrix factorization (NMF) has become very popular as it is…

Computer Vision and Pattern Recognition · Computer Science 2016-10-07 Gabriella Casalino , Nicolas Gillis

The study of representations is widespread across fields, including neuroscience, psychology, and artificial intelligence. While representations are often studied and compared through similarities between stimuli, current methods provide…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Florian P. Mahner , Ka Chun Lam , Francisco Pereira , Martin N. Hebart

Nonnegative Matrix Factorization (NMF) is a widely-used data analysis technique, and has yielded impressive results in many real-world tasks. Generally, existing NMF methods represent each sample with several centroids, and find the optimal…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Mulin Chen , Xuelong Li

Modern biomedical datasets are increasingly high dimensional and exhibit complex correlation structures. Generalized Linear Mixed Models (GLMMs) have long been employed to account for such dependencies. However, proper specification of the…

Tensor decomposition is an effective tool for learning multi-way structures and heterogeneous features from high-dimensional data, such as the multi-view images and multichannel electroencephalography (EEG) signals, are often represented by…

Machine Learning · Computer Science 2022-06-29 Wanguang Yin , Youzhi Qu , Zhengming Ma , Quanying Liu

Nonnegative Matrix Factorization (NMF) is an unsupervised learning algorithm that produces a linear, parts-based approximation of a data matrix. NMF constructs a nonnegative low rank basis matrix and a nonnegative low rank matrix of weights…

Machine Learning · Statistics 2020-12-08 Matthew Corsetti , Ernest Fokoué

Non-negative matrix factorization (NMF) is a dimensionality reduction technique which tends to produce a sparse representation of data. Commonly, the error between the actual and recreated matrices is used as an objective function, but this…

Machine Learning · Computer Science 2019-02-06 Steven Squires , Adam Prugel Bennett , Mahesan Niranjan

Low rank matrix factorisation is often used in recommender systems as a way of extracting latent features. When dealing with large and sparse datasets, traditional recommendation algorithms face the problem of acquiring large, unrestrained,…

Machine Learning · Computer Science 2018-07-17 Shuai Jiang , Kan Li , Richard Yi Da Xu

Dimensionality Reduction plays a pivotal role in improving feature learning accuracy and reducing training time by eliminating redundant features, noise, and irrelevant data. Nonnegative Matrix Factorization (NMF) has emerged as a popular…

Machine Learning · Computer Science 2024-05-07 Farid Saberi-Movahed , Kamal Berahman , Razieh Sheikhpour , Yuefeng Li , Shirui Pan

In this paper we consider the Nonnegative Matrix Factorization (NMF) problem: given an (elementwise) nonnegative matrix $V \in \R_+^{m\times n}$ find, for assigned $k$, nonnegative matrices $W\in\R_+^{m\times k}$ and $H\in\R_+^{k\times n}$…

Optimization and Control · Mathematics 2014-07-08 Lorenzo Finesso , Peter Spreij

There has been a recent critical need to study fairness and bias in machine learning (ML) algorithms. Since there is clearly no one-size-fits-all solution to fairness, ML methods should be developed alongside bias mitigation strategies that…

Machine Learning · Computer Science 2026-03-06 Lara Kassab , Erin George , Deanna Needell , Haowen Geng , Nika Jafar Nia , Aoxi Li

The establishment of robust target appearance model over time is an overriding concern in visual tracking. In this paper, we propose an inverse nonnegative matrix factorization (NMF) method for robust appearance modeling. Rather than using…

Computer Vision and Pattern Recognition · Computer Science 2016-01-13 Fanghui Liu , Tao Zhou , Keren Fu , Irene Y. H. Gu , Jie Yang

In this paper we explore avenues for improving the reliability of dimensionality reduction methods such as Non-Negative Matrix Factorization (NMF) as interpretive exploratory data analysis tools. We first explore the difficulties of the…

Artificial Intelligence · Computer Science 2009-04-22 Nikolaos Vasiloglou , Alexander G. Gray , David V. Anderson
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