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Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous…

Biological Physics · Physics 2019-04-10 Neelam Hari , Priyanka Patel , Jacqueline Ross , Kevin Hicks , Frédérique Vanholsbeeck

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

We report a proof-of-concept demonstration of a tunable infrared (IR) optical coherence tomography (OCT) technique with detection of only visible range photons. Our method is based on the nonclassical interference of frequency correlated…

Quantum Physics · Physics 2018-04-09 Anna V. Paterova , Hongzhi Yang , Chengwu An , Dmitry A. Kalashnikov , Leonid A. Krivitsky

Using spectrally correlated photon pairs instead of classical laser light and coincidence detection instead of light intensity detection, Quantum Optical Coherence Tomography (Q-OCT) outperforms classical OCT in several experimental terms.…

Quantum Physics · Physics 2025-10-06 Sylwia M. Kolenderska , Crislane Vieira de Brito , Piotr Kolenderski

Optical coherence tomography angiography (OCTA) performs non-invasive visualization and characterization of microvasculature in research and clinical applications mainly in ophthalmology and dermatology. A wide variety of instruments,…

Polarization-sensitive optical coherence tomography (PS-OCT) extends OCT by analyzing the polarization states of backscattered light to quantify tissue birefringence. However, conventional implementations require polarization-diverse…

Mid-infrared light scatters much less than shorter wavelengths, allowing greatly enhanced penetration depths for optical imaging techniques such as optical coherence tomography (OCT). However, both detection and broadband sources in the…

A resolution enhancement technique for optical coherence tomography (OCT), based on Generative Adversarial Networks (GANs), was developed and investigated. GANs have been previously used for resolution enhancement of photography and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Kaicheng Liang , Xinyu Liu , Si Chen , Jun Xie , Wei Qing Lee , Linbo Liu , Hwee Kuan Lee

We demonstrate optical coherence tomography based on an SU(1,1) nonlinear interferometer with high-gain parametric down-conversion. For imaging and sensing applications, this scheme promises to outperform previous experiments working at low…

Quantum Physics · Physics 2020-08-31 Gerard J. Machado , Gaetano Frascella , Juan P. Torres , Maria V. Chekhova

Optical Deflectometric Tomography (ODT) provides an accurate characterization of transparent materials whose complex surfaces present a real challenge for manufacture and control. In ODT, the refractive index map (RIM) of a transparent…

Computer Vision and Pattern Recognition · Computer Science 2013-10-31 Adriana Gonzalez , Laurent Jacques , Christophe De Vleeschouwer , Philippe Antoine

Optical Coherence Tomography Angiography (OCTA) is a crucial imaging technique for visualizing retinal vasculature and diagnosing eye diseases such as diabetic retinopathy and glaucoma. However, precise segmentation of OCTA vasculature…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Shun Zou , Zhuo Zhang , Guangwei Gao

We report an algorithm, based on quantum optics formulation, where a coherent state is used as the elementary quantum resource for the image representation. We provide an architecture with constituent optical elements in linear order with…

Quantum Physics · Physics 2024-10-01 Vivek Mehta , Sonali Jana , Utpal Roy

Background: Cervical cancer seriously affects the health of the female reproductive system. Optical coherence tomography (OCT) emerged as a non-invasive, high-resolution imaging technology for cervical disease detection. However, OCT image…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Kaiyi Chen , Qingbin Wang , Yutao Ma

Large-volume optical coherence tomography (OCT)-setups employ scanning mirrors and suffer from non-linear geometric distortion artifacts in which the degree of distortion is determined by the maximum angles over which the mirrors rotate. In…

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

We present an experimental demonstration of quantum optical coherence tomography (QOCT). The technique makes use of an entangled twin-photon light source to carry out axial optical sectioning. QOCT is compared to conventional optical…

Quantum Physics · Physics 2019-10-18 Magued B. Nasr , Bahaa E. A. Saleh , Alexander V. Sergienko , Malvin C. Teich