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In this note, we describe an experiment on portfolio optimization using the Quadratic Unconstrained Binary Optimization (QUBO) formulation. The dataset we use is taken from a real-world problem for which a classical solution is currently…

One of the problems frequently mentioned as a candidate for quantum advantage is that of selecting a portfolio of financial assets to maximize returns while minimizing risk. In this paper we formulate several real-world constraints for use…

Materials Science · Physics 2022-03-10 Salvatore Certo , Anh Dung Pham , Daniel Beaulieu

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

This paper explores the applications of quantum annealing (QA) and classical simulated annealing (SA) to a suite of combinatorial optimization problems in machine learning, namely feature selection, instance selection, and clustering. We…

Quantum Physics · Physics 2025-07-22 Chloe Pomeroy , Aleksandar Pramov , Karishma Thakrar , Lakshmi Yendapalli

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

We study quantum computing algorithms for solving certain constrained resource allocation problems we coin as Mission Covering Optimization (MCO). We compare formulations of constrained optimization problems using Quantum Annealing…

Quantum Physics · Physics 2022-05-05 Massimiliano Cutugno , Annarita Giani , Paul M. Alsing , Laura Wessing , Austars Schnore

We present a novel formulation of structural design optimization problems specifically tailored to be solved by quantum annealing (QA). Structural design optimization aims to find the best, i.e., material-efficient yet high-performance,…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Fabian Key , Lukas Freinberger

As consequences of disruptions in railway traffic affect passenger experience/satisfaction, appropriate rerouting and/or rescheduling is necessary. These problems are known to be NP-hard, given the numerous restrictions of traffic nature.…

Emerging Technologies · Computer Science 2022-10-06 Krzysztof Domino , Akash Kundu , Özlem Salehi , Krzysztof Krawiec

Quantum annealing offers a novel approach to finding the optimal solutions for a variety of computational problems, where the quantum annealing controls influence the observed performance and error mechanisms by tuning the underlying…

Quantum Physics · Physics 2021-01-13 Erica Grant , Travis Humble , Benjamin Stump

Quantum annealers can solve QUBO problems efficiently but struggle with continuous optimization tasks like regression due to their discrete nature. We introduce Quadratic Continuous Quantum Optimization (QCQO), an anytime algorithm that…

Quantum Physics · Physics 2026-01-01 Sascha Mücke , Thore Gerlach , Nico Piatkowski

Portfolio optimization (PO) is extensively employed in financial services to assist in achieving investment objectives. By providing an optimal asset allocation, PO effectively balances the risk and returns associated with investments.…

Quantum Physics · Physics 2024-07-09 Zhijie Tang , Alex Lu Dou , Arit Kumar Bishwas

Quadratic unconstrained binary optimization (QUBO) is the mathematical formalism for phrasing and solving a class of optimization problems that are combinatorial in nature. Due to their natural equivalence with the two dimensional Ising…

Quantum annealing (QA) is a heuristic search algorithm that can run on Adiabatic Quantum Computation (AQC) processors to solve combinatorial optimization problems. Although theoretical studies and simulations on classic hardware have shown…

This paper studies quantum optimization baselines for the Generalized Traveling Salesman Problem (GTSP), a clustered routing problem that naturally models variant selection and sequencing problems under discrete alternatives. We propose a…

Operation management of nuclear power plants consists of several computationally hard problems. Searching for an in-core fuel loading pattern is among them. The main challenge of this combinatorial optimization problem is the exponential…

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

In this work, we review quantum approaches to combinatorial optimization, with the aim of bridging theoretical developments and industrial relevance. We first survey the main families of quantum algorithms, including Quantum Annealing, the…

Quantum Physics · Physics 2026-03-20 Hala Hawashin , Deep Nath , Marco Alberto Javarone

Real-world optimization problems must undergo a series of transformations before becoming solvable on current quantum hardware. Even for a fixed problem, the number of possible transformation paths -- from industry-relevant formulations…

Quantum annealing (QA) is a quantum computing algorithm that works on the principle of Adiabatic Quantum Computation (AQC), and it has shown significant computational advantages in solving combinatorial optimization problems such as vehicle…

Optimization and Control · Mathematics 2020-05-28 Ramkumar Harikrishnakumar , Saideep Nannapaneni , Nam H. Nguyen , James E. Steck , Elizabeth C. Behrman
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