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Localization microscopy is an imaging technique in which the positions of individual nanoscale point emitters (e.g. fluorescent molecules) are determined at high precision from their images. This is the key ingredient in…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Elias Nehme , Daniel Freedman , Racheli Gordon , Boris Ferdman , Lucien E. Weiss , Onit Alalouf , Reut Orange , Tomer Michaeli , Yoav Shechtman

Image Phase Alignment Super-Sampling (ImPASS) is a computational imaging algorithm for converting a sequence of displaced low-resolution images into a single high-resolution image. The method consists of a unique combination of Phase…

Optics · Physics 2025-09-01 James N. Caron

Malaria is one of the most common diseases caused by mosquitoes and is a great public health problem worldwide. Currently, for malaria diagnosis the standard technique is microscopic examination of a stained blood film. We propose use of…

Medical Physics · Physics 2016-08-25 Purnima Pandit , A. Anand

Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams…

Ptychography is a popular imaging technique that combines diffractive imaging with scanning microscopy. The technique consists of a coherent beam that is scanned across an object in a series of overlapping positions, leading to reliable and…

Numerical Analysis · Mathematics 2024-08-08 Ricardo Parada , Samy Wu Fung , Stanley Osher

We present a novel approach to implement compressive sensing in laser scanning microscopes (LSM), specifically in image scanning microscopy (ISM), using a single-photon avalanche diode (SPAD) array detector. Our method addresses two…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Ajay Gunalan , Marco Castello , Simonluca Piazza , Shunlei Li , Alberto Diaspro , Leonardo S. Mattos , Paolo Bianchini

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

Automated and computerised control of scientific instrumentation is almost ubiquitous in the modern laboratory. Most instrumentation is controlled over decades old communication busses or is accessed via proprietary system libraries. This…

Instrumentation and Detectors · Physics 2022-01-07 Joel T. Collins , Joe Knapper , Julian Stirling , Samuel McDermott , Richard Bowman

The Spreading Projection Algorithm for Rapid K-space samplING, or SPARKLING, is an optimization-driven method that has been recently introduced for accelerated 2D T2*-w MRI using compressed sensing. It has then been extended to address 3D…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-26 Chaithya G R , Pierre Weiss , Guillaume Daval-Frérot , Aurélien Massire , Alexandre Vignaud , Philippe Ciuciu

Real-time 3D fluorescence microscopy is crucial for the spatiotemporal analysis of live organisms, such as neural activity monitoring. The eXtended field-of-view light field microscope (XLFM), also known as Fourier light field microscope,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Josué Page Vizcaíno , Panagiotis Symvoulidis , Zeguan Wang , Jonas Jelten , Paolo Favaro , Edward S. Boyden , Tobias Lasser

This paper presents a systematic solution for the intelligent recognition and automatic analysis of microscopy images. We developed a data engine that generates high-quality annotated datasets through a combination of the collection of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Yanhui Hong , Nan Wang , Zhiyi Xia , Haoyi Tao , Xi Fang , Yiming Li , Jiankun Wang , Peng Jin , Xiaochen Cai , Shengyu Li , Ziqi Chen , Zezhong Zhang , Guolin Ke , Linfeng Zhang

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

Versatile, sterically accessible imaging systems capable of in vivo rapid volumetric functional and structural imaging deep in the brain continue to be a limiting factor in neuroscience research. Towards overcoming this obstacle, we present…

Neurons and Cognition · Quantitative Biology 2018-05-10 Manish Kumar , Sandeep Kishore , Jordan Nasenbeny , David McLean , Yevgenia Kozorovitskiy

A unique sample independent 3D self calibration methodology is tested on a unique optical coherence tomography and multi-spectral scanning laser ophthalmoscope (OCT-SLO) hybrid system. Operators visual cognition is replaced by computer…

Medical Physics · Physics 2024-08-08 Mayank Goswami

Malaria is considered one of the deadliest diseases in today world which causes thousands of deaths per year. The parasites responsible for malaria are scientifically known as Plasmodium which infects the red blood cells in human beings.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-22 Aayush Kumar , Sanat B Singh , Suresh Chandra Satapathy , Minakhi Rout

Raman microscopy is a powerful method combining non-invasiveness with no special sample preparation. Because of this remarkable simplicity, it has been widely exploited in many fields, ranging from life and materials sciences, to…

The first choice in diagnostic imaging for patients suffering from peripheral arterial disease is 2D ultrasound (US). However, for a proper imaging process, a skilled and experienced sonographer is required. Additionally, it is a highly…

To accelerate MRI, the field of compressed sensing is traditionally concerned with optimizing the image quality after a partial undersampling of the measurable $\textit{k}$-space. In our work, we propose to change the focus from the quality…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Artem Razumov , Oleg Y. Rogov , Dmitry V. Dylov

Microscopy, in particular scanning probe and electron microscopy, has been pivotal in improving our understanding of structure-function relationships at the nanoscale and is by now ubiquitous in most research characterization labs and…

We present an overview of the performances of a plenoptic microscope which combines the high sensitivity of a laser optical feedback imaging setup , the high resolution of optical synthetic aperture and a shot noise limited signal to noise…

Optics · Physics 2015-06-19 W Glastre , O Hugon , O Jacquin , H Guillet de Chatellus , E Lacot