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Clinicians are increasingly looking towards machine learning to gain insights about patient evolutions. We propose a novel approach named Multi-Modal UMLS Graph Learning (MMUGL) for learning meaningful representations of medical concepts…

Machine Learning · Computer Science 2024-02-07 Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Scientific results are communicated visually in the literature through diagrams, visualizations, and photographs. These information-dense objects have been largely ignored in bibliometrics and scientometrics studies when compared to…

Social and Information Networks · Computer Science 2016-05-30 Po-shen Lee , Jevin D. West , Bill Howe

Vector data is prevalent across business and scientific applications, and its popularity is growing with the proliferation of learned embeddings. Vector data collections often reach billions of vectors with thousands of dimensions, thus,…

Information Retrieval · Computer Science 2025-09-08 Ilias Azizi , Karima Echihabi , Themis Palpanas

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Knowledge graphs are a key technique for linking and integrating cross-domain data, concepts, tools, and knowledge to enable data-driven analytics. As much of the worlds data have become massive in size, visualizing graph entities and their…

Human-Computer Interaction · Computer Science 2023-04-21 Sizhe Wang , Wenwen Li , Zhining Gu

Image-based characterization and disease understanding involve integrative analysis of morphological, spatial, and topological information across biological scales. The development of graph convolutional networks (GCNs) has created the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Kexin Ding , Mu Zhou , Zichen Wang , Qiao Liu , Corey W. Arnold , Shaoting Zhang , Dimitri N. Metaxas

Background : Knowledge is evolving over time, often as a result of new discoveries or changes in the adopted methods of reasoning. Also, new facts or evidence may become available, leading to new understandings of complex phenomena. This is…

Computation and Language · Computer Science 2023-04-24 Ayoub Harnoune , Maryem Rhanoui , Mounia Mikram , Siham Yousfi , Zineb Elkaimbillah , Bouchra El Asri

The continuous growth of scientific literature brings innovations and, at the same time, raises new challenges. One of them is related to the fact that its analysis has become difficult due to the high volume of published papers for which…

Computation and Language · Computer Science 2020-11-06 Danilo Dessì , Francesco Osborne , Diego Reforgiato Recupero , Davide Buscaldi , Enrico Motta

Spatial transcriptomics methods capture cellular measurements such as gene expression and cell types at specific locations in a cell, helping provide a localized picture of tissue health. Traditional visualization techniques superimpose the…

Quantitative Methods · Quantitative Biology 2024-10-16 Siyuan Zhao , G. Elisabeta Marai

Graphs are structured data that models complex relations between real-world entities. Heterophilic graphs, where linked nodes are prone to be with different labels or dissimilar features, have recently attracted significant attention and…

Social and Information Networks · Computer Science 2025-03-21 Chenghua Gong , Yao Cheng , Jianxiang Yu , Can Xu , Caihua Shan , Siqiang Luo , Xiang Li

Motivation: Networks underlie the generation and interpretation of many biological datasets: gene networks shed light on the regulatory structure of the genome, and cell networks can capture structure of the tumor micro-environment.…

Machine Learning · Statistics 2026-03-18 Bailey Andrew , Erica L. Harris , James A. Poulter , David R. Westhead , Luisa Cutillo

This paper provides theoretical and computational developments in statistical shape analysis of shape graphs, and demonstrates them using analysis of complex data from retinal blood-vessel (RBV) networks. The shape graphs are represented by…

Methodology · Statistics 2022-11-29 Aditi Basu Bal , Xiaoyang Guo , Tom Needham , Anuj Srivastava

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

Node-link diagrams are widely used to visualize graphs. Most graph layout algorithms only use graph topology for aesthetic goals (e.g., minimize node occlusions and edge crossings) or use node attributes for exploration goals (e.g.,…

Data Structures and Algorithms · Computer Science 2023-01-20 Leixian Shen , Zhiwei Tai , Enya Shen , Jianmin Wang

Node-link diagrams are a popular method for representing graphs that capture relationships between individuals, businesses, proteins, and telecommunication endpoints. However, node-link diagrams may fail to convey insights regarding graph…

Social and Information Networks · Computer Science 2023-09-20 Paul Rosen , Mustafa Hajij , Bei Wang

Vast amounts of heterogeneous knowledge are becoming publicly available in the form of knowledge graphs, often linking multiple sources of data that have never been together before, and thereby enabling scholars to answer many new research…

Artificial Intelligence · Computer Science 2024-10-10 Xander Wilcke , Rick Mourits , Auke Rijpma , Richard Zijdeman

In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality…

Molecular Networks · Quantitative Biology 2007-05-23 Oliver Mason , Mark Verwoerd

Graphs are widely used as a popular representation of the network structure of connected data. Graph data can be found in a broad spectrum of application domains such as social systems, ecosystems, biological networks, knowledge graphs, and…

Machine Learning · Computer Science 2021-05-04 Feng Xia , Ke Sun , Shuo Yu , Abdul Aziz , Liangtian Wan , Shirui Pan , Huan Liu

A broad spectrum of data from different modalities are generated in the healthcare domain every day, including scalar data (e.g., clinical measures collected at hospitals), tensor data (e.g., neuroimages analyzed by research institutes),…

Machine Learning · Computer Science 2018-03-28 Bokai Cao

Knowledge graphs (KGs) serve as powerful tools for organizing and representing structured knowledge. While their utility is widely recognized, challenges persist in their automation and completeness. Despite efforts in automation and the…

Artificial Intelligence · Computer Science 2024-05-07 Mutahira Khalid , Raihana Rahman , Asim Abbas , Sushama Kumari , Iram Wajahat , Syed Ahmad Chan Bukhari