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Scanning tunneling spectroscopy measures how a single electron with definite energy propagates between a sample surface and the tip of a scanning tunneling microscope. In the simplest description, the differential conductance measured is…

Mesoscale and Nanoscale Physics · Physics 2019-05-07 Mikko M. Ervasti , Fabian Schulz , Peter Liljeroth , Ari Harju

We have developed a controlled and highly reproducible method of making nanometer-spaced electrodes using electromigration in ambient lab conditions. This advance will make feasible single molecule measurements of macromolecules with…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 D. R. Strachan , D. E. Smith , D. E. Johnston , T. -H. Park , M. J. Therien , D. A. Bonnell , A. T. Johnson

We investigate the thermopower of single molecules weakly coupled to metallic leads. We model the molecule in terms of the relevant electronic orbitals coupled to phonons corresponding to both internal vibrations and to oscillations of the…

Mesoscale and Nanoscale Physics · Physics 2009-09-29 Jens Koch , Felix von Oppen , Yuval Oreg , Eran Sela

Phase separation and transitions among different molecular states are ubiquitous in living cells. Such transitions can be governed by local equilibrium thermodynamics or by active processes controlled by biological fuel. It remains largely…

Biological Physics · Physics 2021-11-24 G. Bartolucci , O. Adame-Arana , X. Zhao , C. A. Weber

The question of characterization of the degree of non-equilibrium activity in active matter systems is studied in the context of a stochastic microswimmer model driven by a chemical cycle. The resulting dynamical properties and entropy…

Statistical Mechanics · Physics 2024-05-27 Michalis Chatzittofi , Jaime Agudo-Canalejo , Ramin Golestanian

We propose a simple model to study resonant tunneling through an organic molecule between to conducting leads, taking into account the vibrational modes of the molecule. We solve the model approximately analytically in the weak coupling…

Mesoscale and Nanoscale Physics · Physics 2011-08-24 Sergei Kruchinin , Thomas Pruschke

Achieving dynamic manipulation and control of single molecules at high spatio-temporal resolution is pivotal for advancing atomic-scale computing and nanorobotics. However, this endeavour is critically challenged by complex nature of atomic…

Atomic and Molecular Clusters · Physics 2024-06-18 Divyam Neer Verma , KV Chinmaya , Jan Heck , G Mohan Rao , Sonia Contera , Moumita Ghosh , Siddharth Ghosh

Molecular dynamics simulations are used to simulate the thermal properties of a model fluid containing nanoparticles (nanofluid). By modelling transient absorption experiments, we show that they provide a reliable determination of…

Materials Science · Physics 2015-06-25 Mihail Vladkov , J. -L. Barrat

We introduce axiomatically a complete thermodynamic formalism for a single macromolecule, either with or without detailed balance, in an isothermal ambient fluid based on its stochastic dynamics. With detailed balance, the novel theory…

Statistical Mechanics · Physics 2007-05-23 Hong Qian

It is understood that molecular conjugation plays an important role in charge transport through single-molecule junctions. Here, we investigate electron transport through an anthraquinone based single-molecule three-terminal device. With…

Mesoscale and Nanoscale Physics · Physics 2016-05-19 M. Koole , J. M. Thijssen , H. Valkenier , J. C. Hummelen , H. S. J. van der Zant

The spectroscopy of free radicals and radical containing entrance-channel complexes embedded in superfluid helium nano-droplets is reviewed. The collection of dopants inside individual droplets in the beam represents a micro-canonical…

Atomic and Molecular Clusters · Physics 2007-08-02 Jochen Küpper , Jeremy M. Merritt

We investigate experimentally the entropy transfer between two distinguishable atomic quantum gases at ultralow temperatures. Exploiting a species-selective trapping potential, we are able to control the entropy of one target gas in…

Single-molecule narrowfield microscopy is a versatile tool to investigate a diverse range of protein dynamics in live cells and has been extensively used in bacteria. Here, we describe how these methods can be extended to larger eukaryotic,…

Subcellular Processes · Quantitative Biology 2016-06-09 Adam J. M. Wollman , Mark C. Leake

Single-molecule detection at a nanometric interface in a femtomolar solution, can take weeks as the encounter rate between the diffusing molecule to be detected and the transducing nano-device is negligibly small. On the other hand, several…

Measuring the electrophoretic mobility of molecules is a powerful experimental approach for investigating biomolecular processes. A frequent challenge in the context of single-particle measurements is throughput, limiting the obtainable…

Optics · Physics 2021-07-26 Xuanhui Meng , Philipp Kukura , Sanli Faez

Two recent experimental (Li, J.~\emphj{et al}, \emph{Proc.\ Natl.\ Acad.\ Sci.\ U.~S.~A.} {\bf 2014}, 111, 1282-1287) and theoretical studies (B\^aldea, I, \emph{Phys.\ Chem.\ Chem.\ Phys.}\ {\bf 2014}, 16, 25942-25949) have addressed the…

Chemical Physics · Physics 2015-09-21 Ioan Baldea

Single molecules in solids have been considered as an attractive class of solid-state single quantum systems because they can be chemically synthesized at low cost to have stable narrow transitions at desired wavelengths. Here we report and…

Applied Physics · Physics 2020-07-01 Shangming Wei , Penglong Ren , Yong He , Pu Zhang , Xue-Wen Chen

Molecular electronics is a fascinating area of research with the ability to tune device properties by a chemical tailoring of organic molecules. However, molecular electronics devices often suffer from dispersion and lack of reproducibility…

Mesoscale and Nanoscale Physics · Physics 2013-02-11 Nicolas Clement , David Guerin , Stephane Pleutin , Sylvie Godey , Dominique Vuillaume

Entropy is one of the key thermodynamic variables reflecting changes in the state of matter. Unlike other thermodynamic variables, it is well-defined also for nonequilibrium steady states through its relation to information. Applying this…

Statistical Mechanics · Physics 2026-04-15 Haim Diamant , Gil Ariel

Every time a chemical reaction occurs, an energy exchange between reactants and environment exists, which is defined as the enthalpy of the reaction. In the last decades, research has resulted in an increasing number of devices at the…