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Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Julian Lo , Morgan Heisler , Vinicius Vanzan , Sonja Karst , Ivana Zadro Matovinovic , Sven Loncaric , Eduardo V. Navajas , Mirza Faisal Beg , Marinko V. Sarunic

The measurement of retinal blood flow (RBF) in capillaries can provide a powerful biomarker for the early diagnosis and treatment of ocular diseases. However, no single modality can determine capillary flowrates with high precision.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Chiao-Yi Wang , Faranguisse Kakhi Sadrieh , Yi-Ting Shen , Shih-En Chen , Sarah Kim , Victoria Chen , Achyut Raghavendra , Dongyi Wang , Osamah Saeedi , Yang Tao

Human veins are important for carrying the blood from the body-parts to the heart. The improper functioning of the human veins may arise from several venous diseases. Varicose vein is one such disease wherein back flow of blood can occur,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Maryam Viqar , Violeta Madjarova , Vipul Baghel , Elena Stoykova

Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) are key diagnostic tools for clinical evaluation and management of retinal diseases. Compared to traditional OCT, OCTA provides richer microvascular…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Renzhi Tian , Jinjie Wang , Wei Yang , Weizhen Li , Haoran Chen , Yiran Zhu , Chengchang Pan , Honggang Qi

Optical coherence tomography angiography (OCTA) has drawn numerous attentions in ophthalmology. However, its data acquisition is time-consuming, because it is based on temporal-decorrelation principle thus requires multiple repeated…

Medical Physics · Physics 2019-10-15 Jianlong Yang , Peng Liu , Lixin Duan , Yan Hu , Jiang Liu

The aortic vessel tree is composed of the aorta and its branching arteries, and plays a key role in supplying the whole body with blood. Aortic diseases, like aneurysms or dissections, can lead to an aortic rupture, whose treatment with…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuan Jin , Antonio Pepe , Jianning Li , Christina Gsaxner , Fen-hua Zhao , Kelsey L. Pomykala , Jens Kleesiek , Alejandro F. Frangi , Jan Egger

Optical Coherence Tomography Angiography (OCTA) is a promising tool for detecting Alzheimer's disease (AD) by imaging the retinal microvasculature. Ophthalmologists commonly use region-based analysis, such as the ETDRS grid, to study OCTA…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Shouyue Liu , Jinkui Hao , Yanwu Xu , Huazhu Fu , Xinyu Guo , Jiang Liu , Yalin Zheng , Yonghuai Liu , Jiong Zhang , Yitian Zhao

Segmentation of the coronary artery is an important task for the quantitative analysis of coronary computed tomography angiography (CCTA) images and is being stimulated by the field of deep learning. However, the complex structures with…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Xiaoyu Yang , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

Retinal vessel segmentation is a crucial step in diagnosing and screening various diseases, including diabetes, ophthalmologic diseases, and cardiovascular diseases. In this paper, we propose an effective and efficient method for vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Zhun Fan , Jiajie Mo , Benzhang Qiu , Wenji Li , Guijie Zhu , Chong Li , Jianye Hu , Yibiao Rong , Xinjian Chen

Optical coherence tomography angiography (OCTA) provides non-invasive visualization of retinal microvasculature, but learning robust representations remains challenging due to sparse vessel structures and strong topological constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Ilerioluwakiiye Abolade , Prince Mireku , Kelechi Chibundu , Peace Ododo , Emmanuel Idoko , Promise Omoigui , Solomon Odelola

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Yankui Sun , Tian Zhang , Yue Zhao , Yufan He

To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Quantitative Methods · Quantitative Biology 2024-11-11 Min Gao , Yukun Guo , Tristan T. Hormel , Jie Wang , Elizabeth White , Dong-Wouk Park , Thomas S. Hwang , Steven T. Bailey , Yali Jia

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Optical coherence tomography angiography (OCTA) is a new imaging modality to visualize retinal microvasculature and has been readily adopted in clinics. High-resolution OCT angiograms are important to qualitatively and quantitatively…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Yuyan Ruan , Dawei Yang , Ziqi Tang , An Ran Ran , Carol Y. Cheung , Hao Chen

Optical coherence tomography angiography (OCTA) requires high transverse sampling density for visualizing retinal and choroidal capillaries. Low transverse sampling causes resolution degradation, such as the angiograms in wide-field OCTA.…

Image and Video Processing · Electrical Eng. & Systems 2020-01-09 Ting Zhou , Kang Zhou , Jianlong Yang , Liyang Fang , Yan Hu , Yitian Zhao , Jun Cheng , Xiangping Chen , Shenghua Gao , Jiang Liu

Optical Coherence Tomography is a technique used to scan the Retina of the eye and check for tears. In this paper, we develop a Convolutional Neural Network Architecture for OCT scan classification. The model is trained to detect Retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Adit Magotra , Aagat Gedam , Tanush Savadi , Emily Li

Structural changes in retinal blood vessels are critical biomarkers for the onset and progression of glaucoma and other ocular diseases. However, current vessel segmentation approaches largely rely on supervised learning and extensive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Cheng Huang , Weizheng Xie , Fan Gao , Yutong Liu , Ruoling Wu , Zeyu Han , Jingxi Qiu , Xiangxiang Wang , Zhenglin Yang , Hao Wang , Yongbin Yu

A polarization-multiplexed, dual-beam setup is proposed to expand the field of view for a swept source optical coherence tomography angiography (OCTA) system. This method used a Wollaston prism to split sample path light into two…

Medical Physics · Physics 2017-10-30 Jianlong Yang , Rahul Chandwani , Rui Zhao , Zhuo Wang , Yali Jia , David Huang , Gangjun Liu
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