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We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

Efficiently utilizing discriminative features is crucial for convolutional neural networks to achieve remarkable performance in medical image segmentation and is also important for model generalization across multiple domains, where letting…

Computer Vision and Pattern Recognition · Computer Science 2022-05-16 Ran Gu , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Xiaofan Zhang , Guotai Wang , Shaoting Zhang

Convolutional networks (ConvNets) have achieved great successes in various challenging vision tasks. However, the performance of ConvNets would degrade when encountering the domain shift. The domain adaptation is more significant while…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Qi Dou , Cheng Ouyang , Cheng Chen , Hao Chen , Pheng-Ann Heng

Convolutional neural networks (CNNs) have led to significant improvements in the semantic segmentation of images. When source and target datasets come from different modalities, CNN performance suffers due to domain shift. In such cases…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Serban Stan , Mohammad Rostami

Unsupervised domain adaptation (UDA) aims to learn a model trained on source domain and performs well on unlabeled target domain. In medical image segmentation field, most existing UDA methods depend on adversarial learning to address the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Shaolei Liu , Siqi Yin , Linhao Qu , Manning Wang

Tremendous research efforts have been made to thrive deep domain adaptation (DA) by seeking domain-invariant features. Most existing deep DA models only focus on aligning feature representations of task-specific layers across domains while…

Computer Vision and Pattern Recognition · Computer Science 2020-05-15 Shuang Li , Chi Harold Liu , Qiuxia Lin , Binhui Xie , Zhengming Ding , Gao Huang , Jian Tang

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Domain-invariant representation learning is a powerful method for domain generalization. Previous approaches face challenges such as high computational demands, training instability, and limited effectiveness with high-dimensional data,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Yuheng Xu , Taiping Zhang

Single-source domain generalization (SDG) aims to learn a model from a single source domain that can generalize well on unseen target domains. This is an important task in computer vision, particularly relevant to medical imaging where…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Boqi Chen , Yuanzhi Zhu , Yunke Ao , Sebastiano Caprara , Reto Sutter , Gunnar Rätsch , Ender Konukoglu , Anna Susmelj

Efficient medical image segmentation aims to provide accurate pixel-wise predictions for medical images with a lightweight implementation framework. However, lightweight frameworks generally fail to achieve superior performance and suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Xingqun Qi , Zhuojie Wu , Min Ren , Muyi Sun , Caifeng Shan , Zhenan Sun

Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Xi Chen , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

The capability of generalization to unseen domains is crucial for deep learning models when considering real-world scenarios. However, current available medical image datasets, such as those for COVID-19 CT images, have large variations of…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Qiangguo Jin , Hui Cui , Changming Sun , Zhaopeng Meng , Leyi Wei , Ran Su

With the widespread success of deep learning in biomedical image segmentation, domain shift becomes a critical and challenging problem, as the gap between two domains can severely affect model performance when deployed to unseen data with…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Ping Gong , Wenwen Yu , Qiuwen Sun , Ruohan Zhao , Junfeng Hu

For medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ziqi Zhou , Lei Qi , Xin Yang , Dong Ni , Yinghuan Shi

Single source domain generalization (SDG) holds promise for more reliable and consistent image segmentation across real-world clinical settings particularly in the medical domain, where data privacy and acquisition cost constraints often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

Due to domain shifts across diverse medical imaging modalities, learned segmentation models often suffer significant performance degradation during deployment. We posit that these domain shifts can generally be categorized into two main…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Zhaolin Chen

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ran Gu , Guotai Wang , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Yinan Chen , Wenjun Liao , Shichuan Zhang , Kang Li , Dimitris N. Metaxas , Shaoting Zhang

Deep learning (DL) has shown remarkable success in various medical imaging data analysis applications. However, it remains challenging for DL models to achieve good generalization, especially when the training and testing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Yuemeng Li , Yong Fan
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