English
Related papers

Related papers: Spike2Vec: An Efficient and Scalable Embedding App…

200 papers

Genomic surveillance of SARS-CoV-2 has been instrumental in tracking the spread and evolution of the virus during the pandemic. The availability of SARS-CoV-2 molecular sequences isolated from infected individuals, coupled with phylodynamic…

Applications · Statistics 2021-08-31 Lorenzo Cappello , Jaehee Kim , Sifan Liu , Julia A. Palacios

Advances in next-generation metagenome sequencing have the potential to revolutionize the point-of-care diagnosis of novel pathogen infections, which could help prevent potential widespread transmission of diseases. Given the high volume of…

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

Complex multi-step attacks have caused significant damage to numerous critical infrastructures. To detect such attacks, graph neural network based methods have shown promising results by modeling the system's events as a graph. However,…

Cryptography and Security · Computer Science 2024-06-17 Wei Liu , Peng Gao , Haotian Zhang , Ke Li , Weiyong Yang , Xingshen Wei , Jiwu Shu

Experimental studies support the notion of spike-based neuronal information processing in the brain, with neural circuits exhibiting a wide range of temporally-based coding strategies to rapidly and efficiently represent sensory stimuli.…

Neural and Evolutionary Computing · Computer Science 2020-08-18 Brian Gardner , André Grüning

Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

Fast screening of drug molecules based on the ligand binding affinity is an important step in the drug discovery pipeline. Graph neural fingerprint is a promising method for developing molecular docking surrogates with high throughput and…

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

SARS-CoV-2 is an upper respiratory system RNA virus that has caused over 3 million deaths and infecting over 150 million worldwide as of May 2021. With thousands of strains sequenced to date, SARS-CoV-2 mutations pose significant challenges…

Quantitative Methods · Quantitative Biology 2021-11-15 Yanyi Ding , Zhiyi Kuang , Yuxin Pei , Jeff Tan , Ziyu Zhang , Joseph Konan

The current COVID-19 global pandemic caused by the SARS-CoV-2 betacoronavirus has resulted in over a million deaths and is having a grave socio-economic impact, hence there is an urgency to find solutions to key research challenges. Much of…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-14 Jamie J Alnasir

The importance of the working document is that it allows the analysis of information and cases associated with (SARS-CoV-2) COVID-19, based on the daily information generated by the Government of Mexico through the Secretariat of Health,…

Computers and Society · Computer Science 2021-12-03 Medel-Ramírez Carlos , Medel-López Hilario , Lara-Mérida Jennifer

Motivation: In this paper we present the latest release of EBIC, a next-generation biclustering algorithm for mining genetic data. The major contribution of this paper is adding support for big data, making it possible to efficiently run…

Genomics · Quantitative Biology 2024-09-05 Patryk Orzechowski , Jason H. Moore

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

Vector data is prevalent across business and scientific applications, and its popularity is growing with the proliferation of learned embeddings. Vector data collections often reach billions of vectors with thousands of dimensions, thus,…

Information Retrieval · Computer Science 2025-09-09 Ilias Azizi , Karima Echihab , Themis Palpanas , Vassilis Christophides

Effective molecular representations are essential for ligand-based virtual screening. We investigate how quantum data embedding strategies can improve this task by developing and evaluating a family of quantum-classical hybrid embedding…

Quantum Physics · Physics 2025-12-19 Junggu Choi , Tak Hur , Seokhoon Jeong , Kyle L. Jung , Jun Bae Park , Junho Lee , Jae U. Jung , Daniel K. Park

Neural networks have been shown to be an effective tool for learning algorithms over graph-structured data. However, graph representation techniques---that convert graphs to real-valued vectors for use with neural networks---are still in…

Machine Learning · Computer Science 2018-10-10 Shaileshh Bojja Venkatakrishnan , Mohammad Alizadeh , Pramod Viswanath

Large-scale statistical analysis of data sets associated with genome sequences plays an important role in modern biology. A key component of such statistical analyses is the computation of $p$-values and confidence bounds for statistics…

Applications · Statistics 2011-01-06 Peter J. Bickel , Nathan Boley , James B. Brown , Haiyan Huang , Nancy R. Zhang

Despite the recent success of reconciling spike-based coding with the error backpropagation algorithm, spiking neural networks are still mostly applied to tasks stemming from sensory processing, operating on traditional data structures like…

Neural and Evolutionary Computing · Computer Science 2023-08-25 Dominik Dold , Josep Soler Garrido

SpikeCV is a new open-source computer vision platform for the spike camera, which is a neuromorphic visual sensor that has developed rapidly in recent years. In the spike camera, each pixel position directly accumulates the light intensity…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Yajing Zheng , Jiyuan Zhang , Rui Zhao , Jianhao Ding , Shiyan Chen , Ruiqin Xiong , Zhaofei Yu , Tiejun Huang

Due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) being a novel virus, there are currently no known effective antiviral drugs capable of slowing its progress. To accelerate the discovery of potential drug candidates,…

Biomolecules · Quantitative Biology 2020-09-29 Lokesh Agrawal , Thanasis Poullikkas , Scott Eisenhower , Carlo Monsanto , Ranjith Kumar Bakku