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COVID-19 has shown the importance of having a fast response against pandemics. Finding a novel drug is a very long and complex procedure, and it is possible to accelerate the preliminary phases by using computer simulations. In particular,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-13 Emanuele Vitali , Federico Ficarelli , Mauro Bisson , Davide Gadioli , Massimiliano Fatica , Andrea R. Beccari , Gianluca Palermo

Maintaining computational load balance is important to the performant behavior of codes which operate under a distributed computing model. This is especially true for GPU architectures, which can suffer from memory oversubscription if…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-11-05 Michael E. Rowan , Axel Huebl , Kevin N. Gott , Jack Deslippe , Maxence Thévenet , Remi Lehe , Jean-Luc Vay

Many modern parallel computing systems are heterogeneous at their node level. Such nodes may comprise general purpose CPUs and accelerators (such as, GPU, or Intel Xeon Phi) that provide high performance with suitable energy-consumption…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-19 Suejb Memeti , Lu Li , Sabri Pllana , Joanna Kolodziej , Christoph Kessler

We present the extension of the Tinker-HP package (Lagard\`ere et al., Chem. Sci., 2018,9, 956-972) to the use of Graphics Processing Unit (GPU) cards to accelerate molecular dynamics simulations using polarizable many-body force fields.…

The new Cell processor represents a turning point for computing intensive applications. Here, I show that for molecular dynamics it is possible to reach an impressive sustained performance in excess of 30 Gflops with a peak of 45 Gflops for…

Computational Physics · Physics 2009-11-13 G. De Fabritiis

The high arithmetic performance and intrinsic parallelism of recent graphical processing units (GPUs) can offer a technological edge for molecular dynamics simulations. ACEMD is a production-class bio-molecular dynamics (MD) simulation…

Computational Physics · Physics 2009-02-06 M. J. Harvey , G. Giupponi , G. De Fabritiis

As fusion energy devices advance, plasma simulations are crucial for reactor design. Our work extends BIT1 hybrid parallelization by integrating MPI with OpenMP and OpenACC, focusing on asynchronous multi-GPU programming. Results show…

In drug discovery, molecular docking aims at characterizing the binding of a drug-like molecule to a macromolecule. AutoDock-GPU, a state-of-the-art docking software, estimates the geometrical conformation of a docked ligand-protein complex…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-15 Gabin Schieffer , Ivy Peng

High-performance, multi-core processors are the key to accelerating workloads in several application domains. To continue to scale performance at the limit of Moore's Law and Dennard scaling, software and hardware designers have turned to…

Hardware Architecture · Computer Science 2023-10-27 Changxi Liu , Alen Sabu , Akanksha Chaudhari , Qingxuan Kang , Trevor E. Carlson

The capabilities of CP2K, a density-functional theory package and OMEN, a nano-device simulator, are combined to study transport phenomena from first-principles in unprecedentedly large nanostructures. Based on the Hamiltonian and overlap…

High-performance GPU-accelerated particle filter methods are critical for object detection applications, ranging from autonomous driving, robot localization, to time-series prediction. In this work, we investigate the design, development…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-03 Gabin Schieffer , Nattawat Pornthisan , Daniel Araújo de Medeiros , Stefano Markidis , Jacob Wahlgren , Ivy Peng

We scrutinize how to accelerate the bottleneck operations of Pythonic coupled cluster implementations performed on a \texttt{NVIDIA} Tesla V100S PCIe 32GB (rev 1a) Graphics Processing Unit (GPU). The \texttt{NVIDIA} Compute Unified Device…

Commercial graphics processors (GPUs) have high compute capacity at very low cost, which makes them attractive for general purpose scientific computing. In this paper we show how graphics processors can be used for N-body simulations to…

Computational Engineering, Finance, and Science · Computer Science 2007-06-22 Erich Elsen , V. Vishal , Mike Houston , Vijay Pande , Pat Hanrahan , Eric Darve

With high-performance computing systems now running at exascale, optimizing power-scaling management and resource utilization has become more critical than ever. This paper explores runtime power-capping optimizations that leverage…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-26 Maria Patrou , Thomas Wang , Wael Elwasif , Markus Eisenbach , Ross Miller , William Godoy , Oscar Hernandez

$N$-body simulation serves as a critical method for modeling cosmic evolution and poses a significant challenge in high-performance computing. We present CUBE2, an open-source cosmological $N$-body code emphasizing memory efficiency,…

Instrumentation and Methods for Astrophysics · Physics 2026-03-05 Hao-Ran Yu , Bing-Hang Chen , Kun Xu , Ming-Jie Sheng , Jiaxin Han , Yipeng Jing , Huahua Cui

Numerical integration of stochastic differential equations is commonly used in many branches of science. In this paper we present how to accelerate this kind of numerical calculations with popular NVIDIA Graphics Processing Units using the…

Computational Physics · Physics 2011-05-31 M. Januszewski , M. Kostur

Graphics processing units have been extensively used to accelerate classical molecular dynamics simulations. However, there is much less progress on the acceleration of force evaluations for many-body potentials compared to pairwise ones.…

Computational Physics · Physics 2017-06-27 Zheyong Fan , Wei Chen , Ville Vierimaa , Ari Harju

The Kernel Polynomial Method (KPM) is one of the fast diagonalization methods used for simulations of quantum systems in research fields of condensed matter physics and chemistry. The algorithm has a difficulty to be parallelized on a…

Computational Physics · Physics 2011-05-30 Shixun Zhang , Shinichi Yamagiwa , Masahiko Okumura , Seiji Yunoki

Computational biology has increasingly turned to agent-based modeling to explore complex biological systems. Biological diffusion (diffusion, decay, secretion, and uptake) is a key driver of biological tissues. GPU computing can vastly…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-27 Matt Stack , Paul Macklin , Robert Searles , Sunita Chandrasekaran

In drug discovery, molecular docking is the task in charge of estimating the position of a molecule when interacting with the docking site. This task is usually used to perform screening of a large library of molecules, in the early phase…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-21 Emanuele Vitali , Davide Gadioli , Gianluca Palermo , Andrea Beccari , Carlo Cavazzoni , Cristina Silvano
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