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Machine learning has transformed material discovery for inorganic compounds and small molecules, yet polymers remain largely inaccessible to these methods. While data scarcity is often cited as the primary bottleneck, we demonstrate that…

Machine Learning · Computer Science 2025-12-09 Jihun Ahn , Gabriella Pasya Irianti , Vikram Thapar , Su-Mi Hur

Multimodal Large Language Models (MLLMs) have shown exceptional capabilities in vision-language tasks. However, effectively integrating image segmentation into these models remains a significant challenge. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Mengcheng Lan , Chaofeng Chen , Jiaxing Xu , Zongrui Li , Yiping Ke , Xudong Jiang , Yingchen Yu , Yunqing Zhao , Song Bai

Text-guided image-to-image diffusion models excel in translating images based on textual prompts, allowing for precise and creative visual modifications. However, such a powerful technique can be misused for spreading misinformation,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Wenhao Wang , Yifan Sun , Zongxin Yang , Zhentao Tan , Zhengdong Hu , Yi Yang

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li

Recent advances in scanning transmission electron and scanning probe microscopies have opened exciting opportunities in probing the materials structural parameters and various functional properties in real space with angstrom-level…

The crucial field of Optical Chemical Structure Recognition (OCSR) aims to transform chemical structure photographs into machine-readable formats so that chemical databases may be efficiently stored and queried. Although a number of OCSR…

Machine Learning · Computer Science 2025-02-25 Zishuo Lin , Jiajie Wang , Zhe Yan , Peiyong Ma

Finding point-wise correspondences between images is a long-standing problem in image analysis. This becomes particularly challenging for sketch images, due to the varying nature of human drawing style, projection distortions and viewport…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Pablo Navarro , José Ignacio Orlando , Claudio Delrieux , Emmanuel Iarussi

The task here is to predict the toxicological activity of chemical compounds based on the Tox21 dataset, a benchmark in computational toxicology. After a domain-specific overview of chemical toxicity, we discuss current computational…

Machine Learning · Computer Science 2025-10-28 Eduard Popescu , Adrian Groza , Andreea Cernat

Machine learning methods have shown promise in predicting molecular properties, and given sufficient training data machine learning approaches can enable rapid high-throughput virtual screening of large libraries of compounds. Graph-based…

Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…

Molecule optimization is a fundamental task for accelerating drug discovery, with the goal of generating new valid molecules that maximize multiple drug properties while maintaining similarity to the input molecule. Existing generative…

Machine Learning · Computer Science 2024-07-02 Tianfan Fu , Cao Xiao , Xinhao Li , Lucas M. Glass , Jimeng Sun

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Ionic Liquids (ILs) provide a promising solution for CO$_2$ capture and storage to mitigate global warming. However, identifying and designing the high-capacity IL from the giant chemical space requires expensive, and exhaustive simulations…

Chemical Physics · Physics 2022-11-10 Yue Jian , Yuyang Wang , Amir Barati Farimani

The process of screening molecules for desirable properties is a key step in several applications, ranging from drug discovery to material design. During the process of drug discovery specifically, protein-ligand docking, or chemical…

Machine Learning · Computer Science 2022-11-08 Ryien Hosseini , Filippo Simini , Austin Clyde , Arvind Ramanathan

Inspired by its success in natural language processing and computer vision, pre-training has attracted substantial attention in cheminformatics and bioinformatics, especially for molecule based tasks. A molecule can be represented by either…

Quantitative Methods · Quantitative Biology 2021-10-14 Jinhua Zhu , Yingce Xia , Tao Qin , Wengang Zhou , Houqiang Li , Tie-Yan Liu

Multi-modal information retrieval (MMIR) is a rapidly evolving field, where significant progress, particularly in image-text pairing, has been made through advanced representation learning and cross-modality alignment research. However,…

Referring Remote Sensing Image Segmentation (RRSIS) aims to segment target objects in remote sensing (RS) images based on textual descriptions. Although Segment Anything Model 2 (SAM2) has shown remarkable performance in various…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Fu Rong , Meng Lan , Qian Zhang , Lefei Zhang

Advancements in text-to-image generative AI with large multimodal models are spreading into the field of image compression, creating high-quality representation of images at extremely low bit rates. This work introduces novel components to…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Cheng-Lin Wu , Hyomin Choi , Ivan V. Bajić

Molecule representation learning (MRL) methods aim to embed molecules into a real vector space. However, existing SMILES-based (Simplified Molecular-Input Line-Entry System) or GNN-based (Graph Neural Networks) MRL methods either take…

Machine Learning · Computer Science 2021-09-23 Hongwei Wang , Weijiang Li , Xiaomeng Jin , Kyunghyun Cho , Heng Ji , Jiawei Han , Martin D. Burke

Molecular structure elucidation from spectra is a fundamental challenge in molecular science. Conventional approaches rely heavily on expert interpretation and lack scalability, while retrieval-based machine learning approaches remain…

Machine Learning · Computer Science 2025-11-06 Liang Wang , Yu Rong , Tingyang Xu , Zhenyi Zhong , Zhiyuan Liu , Pengju Wang , Deli Zhao , Qiang Liu , Shu Wu , Liang Wang , Yang Zhang