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Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

All simulation approaches eventually face limits in computational scalability when applied to large spatiotemporal domains. This challenge becomes especially apparent in molecular-level particle simulations, where high spatial and temporal…

Computational Physics · Physics 2025-10-23 Matthias Busch , Gregor Häfner , Jiayu Xie , Marius Tacke , Marcus Müller , Christian J. Cyron , Roland C. Aydin

In radiological practice, multi-sequence MRI is routinely acquired to characterize anatomy and tissue. However, due to the heterogeneity of imaging protocols and contra-indications to contrast agents, some MRI sequences, e.g.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Yunjie Chen , Marius Staring , Jelmer M. Wolterink , Qian Tao

Click-through rate (CTR) prediction is one of the fundamental tasks for online advertising and recommendation. While multi-layer perceptron (MLP) serves as a core component in many deep CTR prediction models, it has been widely recognized…

Information Retrieval · Computer Science 2023-12-01 Kelong Mao , Jieming Zhu , Liangcai Su , Guohao Cai , Yuru Li , Zhenhua Dong

Automatic medical image segmentation via convolutional neural networks (CNNs) has shown promising results. However, they may not always be robust enough for clinical use. Sub-optimal segmentation would require clinician's to manually…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Helena Williams , João Pedrosa , Laura Cattani , Susanne Housmans , Tom Vercauteren , Jan Deprest , Jan D'hooge

The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Francesco La Rosa , Erin S Beck , Ahmed Abdulkadir , Jean-Philippe Thiran , Daniel S Reich , Pascal Sati , Meritxell Bach Cuadra

Subcortical segmentation remains challenging despite its important applications in quantitative structural analysis of brain MRI scans. The most accurate method, manual segmentation, is highly labor intensive, so automated tools like…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Aaron Cao , Vishwanatha M. Rao , Kejia Liu , Xinrui Liu , Andrew F. Laine , Jia Guo

Here we present a method for the simultaneous segmentation of white matter lesions and normal-appearing neuroanatomical structures from multi-contrast brain MRI scans of multiple sclerosis patients. The method integrates a novel model for…

Image and Video Processing · Electrical Eng. & Systems 2020-11-26 Stefano Cerri , Oula Puonti , Dominik S. Meier , Jens Wuerfel , Mark Mühlau , Hartwig R. Siebner , Koen Van Leemput

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by diffuse and focal areas of tissue loss. Conventional MRI techniques such as T1-weighted and T2-weighted scans are generally used in the diagnosis and…

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

This paper introduces a novel method for brain segmentation using only FLAIR MRIs, specifically targeting cases where access to other imaging modalities is limited. By leveraging existing automatic segmentation methods, we train a network…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Edern Le Bot , Rémi Giraud , Boris Mansencal , Thomas Tourdias , Josè V. Manjon , Pierrick Coupé

In this paper, a novel label fusion method is proposed for brain magnetic resonance image segmentation. This label fusion method is formulated on a graph, which embraces both label priors from atlases and anatomical priors from target…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Siqi Bao , Albert C. S. Chung

Automated brain tissue segmentation into white matter (WM), gray matter (GM), and cerebro-spinal fluid (CSF) from magnetic resonance images (MRI) is helpful in the diagnosis of neuro-disorders such as epilepsy, Alzheimer's, multiple…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Pulkit Kumar , Pravin Nagar , Chetan Arora , Anubha Gupta

In this work we revisit the most fundamental building block in deep learning, the multi-layer perceptron (MLP), and study the limits of its performance on vision tasks. Empirical insights into MLPs are important for multiple reasons. (1)…

Machine Learning · Computer Science 2023-10-04 Gregor Bachmann , Sotiris Anagnostidis , Thomas Hofmann

The development of automated tools for brain morphometric analysis in infants has lagged significantly behind analogous tools for adults. This gap reflects the greater challenges in this domain due to: 1) a smaller-scaled region of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Lilla Zöllei , Juan Eugenio Iglesias , Yangming Ou , P. Ellen Grant , Bruce Fischl

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

Medical Physics · Physics 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Recent progress on Transformers and multi-layer perceptron (MLP) models provide new network architectural designs for computer vision tasks. Although these models proved to be effective in many vision tasks such as image recognition, there…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Zhengzhong Tu , Hossein Talebi , Han Zhang , Feng Yang , Peyman Milanfar , Alan Bovik , Yinxiao Li

The automatic segmentation of perinatal brain structures in magnetic resonance imaging (MRI) is of utmost importance for the study of brain growth and related complications. While different methods exist for adult and pediatric MRI data,…

To date, several methods have been developed to explain deep learning algorithms for classification tasks. Recently, an adaptation of two of such methods has been proposed to generate instance-level explainable maps in a semantic…

The development of effective treatments for Cerebral Palsy (CP) can begin with the early identification of affected children while they are still in the early stages of the disorder. Pathological issues in the brain can be better diagnosed…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra