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Results and tools on discrete interaction networks are often concerned with Boolean variables, whereas considering more than two levels is sometimes useful. Multivalued networks can be converted to partial Boolean maps, in a way that…

Discrete Mathematics · Computer Science 2018-12-11 Elisa Tonello

Boolean Networks (BNs) describe the time evolution of binary states using logic functions on the nodes of a network. They are fundamental models for complex discrete dynamical systems, with applications in various areas of science and…

Discrete Mathematics · Computer Science 2025-03-26 Van-Giang Trinh , Samuel Pastva , Jordan Rozum , Kyu Hyong Park , Réka Albert

Identification of attractors, that is, stable states and sustained oscillations, is an important step in the analysis of Boolean models and exploration of potential variants. We describe an approach to the search for asynchronous cyclic…

Discrete Mathematics · Computer Science 2024-03-29 Elisa Tonello , Loïc Paulevé

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. We here derive an expression for the number of attractors in…

Molecular Networks · Quantitative Biology 2007-05-23 Björn Samuelsson , Carl Troein

The deterministic dynamics of randomly connected neural networks are studied, where a state of binary neurons evolves according to a discreet-time synchronous update rule. We give a theoretical support that the overlap of systems' states…

Statistical Mechanics · Physics 2015-03-10 Taro Toyoizumi , Haiping Huang

Discrete dynamic models are a powerful tool for the understanding and modeling of large biological networks. Although a lot of progress has been made in developing analysis tools for these models, there is still a need to find approaches…

Molecular Networks · Quantitative Biology 2013-06-14 Jorge G. T. Zañudo , Réka Albert

Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the formalism of Boolean dynamical networks, analyzing the…

Molecular Networks · Quantitative Biology 2021-09-13 Enrico Borriello , Bryan C. Daniels

This paper addresses the problem of finding cycles in the state transition graphs of synchronous Boolean networks. Synchronous Boolean networks are a class of deterministic finite state machines which are used for the modeling of gene…

Molecular Networks · Quantitative Biology 2009-01-29 Elena Dubrova , Maxim Teslenko

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

Molecular Networks · Quantitative Biology 2014-04-23 Yi Ming Zou

Asynchronous Boolean networks are a type of discrete dynamical system in which each variable can take one of two states, and a single variable state is updated in each time step according to pre-selected rules. Boolean networks are popular…

Molecular Networks · Quantitative Biology 2024-10-08 Samuel Pastva , Kyu Hyong Park , Ondrej Huvar , Jordan C Rozum , Reka Albert

We present a computational method for finding attractors (ergodic sets of states) of Boolean networks under asynchronous update. The approach is based on a systematic removal of state transitions to render the state transition graph…

Disordered Systems and Neural Networks · Physics 2010-08-24 Thomas Skodawessely , Konstantin Klemm

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

Systems with many stable configurations abound in nature, both in living and inanimate matter. Their inherent nonlinearity and sensitivity to small perturbations make them challenging to study, particularly in the presence of external…

Adaptation and Self-Organizing Systems · Physics 2023-12-12 Hridesh Kedia , Deng Pan , Jean-Jacques Slotine , Jeremy L. England

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2007-11-21 German A. Enciso , Winfried Just

Random Boolean networks, originally invented as models of genetic regulatory networks, are simple models for a broad class of complex systems that show rich dynamical structures. From a biological perspective, the most interesting networks…

Disordered Systems and Neural Networks · Physics 2009-11-07 Joshua E. S. Socolar , Stuart A. Kauffman

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

We study the stable attractors of a class of continuous dynamical systems that may be idealized as networks of Boolean elements, with the goal of determining which Boolean attractors, if any, are good approximations of the attractors of…

Molecular Networks · Quantitative Biology 2009-11-13 Johannes Norrell , Björn Samuelsson , Joshua E. S. Socolar

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2008-01-30 Winfried Just , German Enciso

Complex diseases can be modeled as damage to intracellular networks that results in abnormal cell behaviors. Network-based dynamic models such as Boolean models have been employed to model a variety of biological systems including those…

Biological Physics · Physics 2016-12-30 Gang Yang , Colin Campbell , Réka Albert

Continuous attractor neural networks generate a set of smoothly connected attractor states. In memory systems of the brain, these attractor states may represent continuous pieces of information such as spatial locations and head directions…

Disordered Systems and Neural Networks · Physics 2019-01-16 Chi Chung Alan Fung , Tomoki Fukai
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