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We propose DiRL, a Diversity-inducing Representation Learning technique for histopathology imaging. Self-supervised learning techniques, such as contrastive and non-contrastive approaches, have been shown to learn rich and effective…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Saarthak Kapse , Srijan Das , Jingwei Zhang , Rajarsi R. Gupta , Joel Saltz , Dimitris Samaras , Prateek Prasanna

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Cervical cancer is a very common and fatal type of cancer in women. Cytopathology images are often used to screen for this cancer. Given that there is a possibility that many errors can occur during manual screening, a computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Wanli Liu , Chen Li , Md Mamunur Rahamana , Tao Jiang , Hongzan Sun , Xiangchen Wu , Weiming Hu , Haoyuan Chen , Changhao Sun , Yudong Yao , Marcin Grzegorzek

Self-supervised learning approaches leverage unlabeled samples to acquire generic knowledge about different concepts, hence allowing for annotation-efficient downstream task learning. In this paper, we propose a novel self-supervised method…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Aiham Taleb , Christoph Lippert , Tassilo Klein , Moin Nabi

Data labeling is often the most challenging task when developing computational pathology models. Pathologist participation is necessary to generate accurate labels, and the limitations on pathologist time and demand for large, labeled…

Quantitative Methods · Quantitative Biology 2021-11-12 Lantian Zhang , Mohamed Amgad , Lee A. D. Cooper

Self-supervised learning has become a popular approach in recent years for its ability to learn meaningful representations without the need for data annotation. This paper proposes a novel image augmentation technique, overlaying images,…

Computer Vision and Pattern Recognition · Computer Science 2023-01-25 Yinheng Li , Han Ding , Shaofei Wang

Recent advances in deep learning have achieved promising performance for medical image analysis, while in most cases ground-truth annotations from human experts are necessary to train the deep model. In practice, such annotations are…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Jianbo Jiao , Richard Droste , Lior Drukker , Aris T. Papageorghiou , J. Alison Noble

We propose a method for representing malignant lymphoma pathology images, from high-resolution cell nuclei to low-resolution tissue images, within a single hyperbolic space using self-supervised learning. To capture morphological changes…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Kei Taguchi , Kazumasa Ohara , Tatsuya Yokota , Hiroaki Miyoshi , Noriaki Hashimoto , Ichiro Takeuchi , Hidekata Hontani

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Applications on Medical Image Analysis suffer from acute shortage of large volume of data properly annotated by medical experts. Supervised Learning algorithms require a large volumes of balanced data to learn robust representations. Often…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Siladittya Manna , Rakesh Dey , Souvik Chakraborty

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

Machine Learning · Computer Science 2021-03-04 Takato Yasuno

Unsupervised learning has made substantial progress over the last few years, especially by means of contrastive self-supervised learning. The dominating dataset for benchmarking self-supervised learning has been ImageNet, for which recent…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Karin Stacke , Jonas Unger , Claes Lundström , Gabriel Eilertsen

Advance in medical imaging is an important part in deep learning research. One of the goals of computer vision is development of a holistic, comprehensive model which can identify tumors from histology slides obtained via biopsies. A major…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Vidit Gautam

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

Self-supervised visual representation learning traditionally focuses on image-level instance discrimination. Our study introduces an innovative, fine-grained dimension by integrating patch-level discrimination into these methodologies. This…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Ali Javidani , Mohammad Amin Sadeghi , Babak Nadjar Araabi

Self-supervised learning (SSL) has recently shown tremendous potential to learn generic visual representations useful for many image analysis tasks. Despite their notable success, the existing SSL methods fail to generalize to downstream…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Chetan L Srinidhi , Anne L Martel

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Recent advances in digital imaging has transformed computer vision and machine learning to new tools for analyzing pathology images. This trend could automate some of the tasks in the diagnostic pathology and elevate the pathologist…

Computer Vision and Pattern Recognition · Computer Science 2020-05-11 Manit Zaveri , Shivam Kalra , Morteza Babaie , Sultaan Shah , Savvas Damskinos , Hany Kashani , H. R. Tizhoosh

High content imaging assays can capture rich phenotypic response data for large sets of compound treatments, aiding in the characterization and discovery of novel drugs. However, extracting representative features from high content images…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Johan Fredin Haslum , Christos Matsoukas , Karl-Johan Leuchowius , Erik Müllers , Kevin Smith
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