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Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

Computer Vision and Pattern Recognition · Computer Science 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

In numerous applications, Fourier-domain optical coherence tomography (FD-OCT) suffers from a limited imaging depth due to signal roll-off, a limited focal range, and autocorrelation noise. Here, we propose a parallel full-field FD-OCT…

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Automatic and accurate segmentation for retinal and choroidal layers of Optical Coherence Tomography (OCT) is crucial for detection of various ocular diseases. However, because of the variations in different equipments, OCT data obtained…

Computer Vision and Pattern Recognition · Computer Science 2019-09-02 Jiexiang Wang , Cheng Bian , Meng Li , Xin Yang , Kai Ma , Wenao Ma , Jin Yuan , Xinghao Ding , Yefeng Zheng

In minimally invasive endovascular procedures, contrast-enhanced angiography remains the most robust imaging technique. However, it is at the expense of the patient and clinician's health due to prolonged radiation exposure. As an…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Alex Ranne , Liming Kuang , Yordanka Velikova , Nassir Navab , Ferdinando Rodriguez y Baena

A new formulation of lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sample…

We present a new approach for constructing optical phase-space-time-frequency tomography (OPSTFT) of an optical wave field. This tomography can be measured by using a novel four-window optical imaging system based on two local oscillator…

Quantum Physics · Physics 2015-05-27 Paul Rojas , Rachel Blaser , Yong Meng Sua , Kim Fook Lee

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

In today's clinics, a cellular-resolution view of the cornea can be achieved only with an in vivo confocal microscope (IVCM) in contact with the eye. Here, we present a common-path Full-field/Spectral-domain OCT microscope (FF/SD OCT),…

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

Optical imaging of blood flow yields critical functional insights into the circulatory system, but its clinical implementation has typically been limited to shallow depths (~1 millimeter) due to light scattering in biological tissue. Here,…

Medical Physics · Physics 2024-06-25 Yang Zhang , Joshua Olick-Gibson , Karteekeya Sastry , Lihong V. Wang

Computational corrections of defocus and aberrations in optical coherence tomography (OCT) offers a promising approach to realize high-resolution imaging with deep imaging depth, but without additional high hardware costs. However, these…

Optics · Physics 2025-10-28 Shuichi Makita , Naoki Fukutake , Lida Zhu , Yoshiaki Yasuno

The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…

The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small…

Medical Physics · Physics 2020-10-21 Jules Scholler , Kassandra Groux , Kate Grieve , Claude Boccara , Pedro Mecê

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

Optics · Physics 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Many biological and soft matter processes occur at high speeds in complex 3D environments, and developing imaging techniques capable of elucidating their dynamics is an outstanding experimental challenge. Here, we introduce Fourier…

Quantum-optical coherence tomography (Q-OCT) is an interferometric technique for axial imaging offering several advantages over conventional methods. Chirped-pulse interferometry (CPI) was recently demonstrated to exhibit all of the…

Quantum Physics · Physics 2009-09-07 Jonathan Lavoie , Rainer Kaltenbaek , Kevin J. Resch

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Optical coherence Doppler tomography (ODT) is an emerging blood flow imaging technique. The fundamental unit of ODT is the 1D depth-resolved trace named raw A-scans (or A-line). A 2D ODT image (B-scan) is formed by reconstructing a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Zhenghong Li , Jiaxiang Ren , Wensheng Cheng , Yanzuo Liu , Congwu Du , Yingtian Pan , Haibin Ling
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