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Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis.…

Purpose: Summarize ICU delirium prediction models published within the past five years. Methods: Electronic searches were conducted in April 2019 using PubMed, Embase, Cochrane Central, Web of Science, and CINAHL to identify peer reviewed…

Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…

Quantitative Methods · Quantitative Biology 2019-09-26 Shigehiko Schamoni , Holger A. Lindner , Verena Schneider-Lindner , Manfred Thiel , Stefan Riezler

We developed MLHO (pronounced as melo), an end-to-end Machine Learning framework that leverages iterative feature and algorithm selection to predict Health Outcomes. MLHO implements iterative sequential representation mining, and feature…

Machine Learning · Statistics 2021-04-28 Hossein Estiri , Zachary H. Strasser , Shawn N. Murphy

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

Machine Learning · Computer Science 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

Predicting time-to-event outcomes in large databases can be a challenging but important task. One example of this is in predicting the time to a clinical outcome for patients in intensive care units (ICUs), which helps to support critical…

Computation · Statistics 2019-08-06 Yingying Xu , Joon Lee , Joel A. Dubin

Recent advances in causal inference techniques, more specifically, in the theory of structural causal models, provide the framework for identification of causal effects from observational data in the cases where the causal graph is…

Machine Learning · Computer Science 2020-10-29 Md Osman Gani , Shravan Kethireddy , Marvi Bikak , Paul Griffin , Mohammad Adibuzzaman

During the coronavirus disease 2019 (COVID-19) pandemic, rapid and accurate triage of patients at the emergency department is critical to inform decision-making. We propose a data-driven approach for automatic prediction of deterioration…

Intensive care occupancy is an important indicator of health care stress that has been used to guide policy decisions during the COVID-19 pandemic. Toward reliable decision-making as a pandemic progresses, estimating the rates at which…

Methodology · Statistics 2023-07-18 Achal Awasthi , Volodymyr M. Minin , Jenny Huang , Daniel Chow , Jason Xu

Intensive Care Unit (ICU) patients often present with complex, overlapping signs of physiological deterioration that require timely escalation of care. Traditional early warning systems, such as SOFA or MEWS, are limited by their focus on…

Machine Learning · Computer Science 2025-09-24 Syed Ahmad Chan Bukhari , Amritpal Singh , Shifath Hossain , Iram Wajahat

Current research efforts largely focus on employing at most one interpretable method to elucidate machine learning (ML) model performance. However, significant barriers remain in translating these interpretability techniques into actionable…

Computers and Society · Computer Science 2025-08-05 Ling Liao , Eva Aagaard

Forecasting models have been influential in shaping decision-making in the COVID-19 pandemic. However, there is concern that their predictions may have been misleading. Here, we dissect the predictions made by four models for the daily…

Populations and Evolution · Quantitative Biology 2020-08-12 Vincent Chin , Noelle I. Samia , Roman Marchant , Ori Rosen , John P. A. Ioannidis , Martin A. Tanner , Sally Cripps

Acute kidney injury (AKI) in critically ill patients is associated with significant morbidity and mortality. Development of novel methods to identify patients with AKI earlier will allow for testing of novel strategies to prevent or reduce…

Machine Learning · Computer Science 2018-11-12 Yikuan Li , Liang Yao , Chengsheng Mao , Anand Srivastava , Xiaoqian Jiang , Yuan Luo

Background: Accurate survival time estimates aid end-of-life medical decision-making. Objectives: Develop an interpretable survival model for elderly residential aged care residents using advanced machine learning. Setting: A major…

Machine Learning · Computer Science 2023-12-11 Teo Susnjak , Elise Griffin

Accurate time prediction of patients' critical events is crucial in urgent scenarios where timely decision-making is important. Though many studies have proposed automatic prediction methods using Electronic Health Records (EHR), their…

Machine Learning · Computer Science 2023-04-14 Kwanhyung Lee , John Won , Heejung Hyun , Sangchul Hahn , Edward Choi , Joohyung Lee

Monitoring patients in ICU is a challenging and high-cost task. Hence, predicting the condition of patients during their ICU stay can help provide better acute care and plan the hospital's resources. There has been continuous progress in…

Computation and Language · Computer Science 2020-01-03 Swaraj Khadanga , Karan Aggarwal , Shafiq Joty , Jaideep Srivastava

We sample aggravated cases following age-structured probabilities from confirmed cases and use ICU occupation data to find a subnotification factor. A logistic fit is then employed to project the progression of the COVID-19 epidemic with…

Physics and Society · Physics 2024-02-14 Rodrigo Veiga , Rodrigo Murta , Renato Vicente

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

Machine Learning · Computer Science 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

Intracerebral hemorrhage (ICH) is a life-risking condition characterized by bleeding within the brain parenchyma. ICU readmission in ICH patients is a critical outcome, reflecting both clinical severity and resource utilization. Accurate…

Machine Learning · Computer Science 2025-01-03 Shuheng Chen , Junyi Fan , Armin Abdollahi , Negin Ashrafi , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The COVID-19 pandemic has had high mortality rates in the elderly and frail worldwide, particularly in care homes. This is driven by the difficulty of isolating care homes from the wider community, the large population sizes within care…

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