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Related papers: Characterizing interdisciplinarity in drug researc…

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Interdisciplinary collaborations now sweep most fields of the natural and life sciences, necessary to tackle the world's most challenging problems. Yet, the scientific enterprise continues to be dominated by old stereotypes:…

Physics and Society · Physics 2018-11-05 Michael Szell , Yifang Ma , Roberta Sinatra

Nowadays, scientific challenges usually require approaches that cross traditional boundaries between academic disciplines, driving many researchers towards interdisciplinarity. Despite its obvious importance, there is a lack of studies on…

Physics and Society · Physics 2016-07-25 Elisa Omodei , Manlio De Domenico , Alex Arenas

Although interdisciplinarity is often touted as a necessity for modern research, the evidence on the relative impact of sectorial versus to interdisciplinary science is qualitative at best. In this paper we leverage the bibliographic data…

Massively multitask neural architectures provide a learning framework for drug discovery that synthesizes information from many distinct biological sources. To train these architectures at scale, we gather large amounts of data from public…

Machine Learning · Statistics 2015-02-10 Bharath Ramsundar , Steven Kearnes , Patrick Riley , Dale Webster , David Konerding , Vijay Pande

Interdisciplinary research is fundamental when it comes to tackling complex problems in our highly interlinked world, and is on the rise globally. Yet, it is unclear why--in an increasingly competitive academic environment--one should…

Digital Libraries · Computer Science 2021-04-28 Ye Sun , Giacomo Livan , Athen Ma , Vito Latora

Causality and causal inference have emerged as core research areas at the interface of modern statistics and domains including biomedical sciences, social sciences, computer science, and beyond. The field's inherently interdisciplinary…

Methodology · Statistics 2025-08-26 Carlos Cinelli , Avi Feller , Guido Imbens , Edward Kennedy , Sara Magliacane , Jose Zubizarreta

The features of collaboration patterns are often considered to be different from discipline to discipline. Meanwhile, collaborating among disciplines is an obvious feature emerged in modern scientific research, which incubates several…

Physics and Society · Physics 2018-03-22 Zheng Xie , Miao Li , Jianping Li , Xiaojun Duan , Zhenzheng Ouyang

Interdisciplinary research has gained prominence as a necessity for addressing complex challenges, yet its impact on early academic careers remains unclear. This study examines how interdisciplinarity during doctoral training influences…

Computers and Society · Computer Science 2025-11-06 Xiang Zheng , Anli Peng , Xi Hong , Cassidy R. Sugimoto , Chaoqun Ni

This paper analyzes the effect of interdisciplinarity on the scientific impact of individual papers. Using all the papers published in Web of Science in 2000, we define the degree of interdisciplinarity of a given paper as the percentage of…

Physics and Society · Physics 2009-08-13 Vincent Lariviere , Yves Gingras

Biomedical research encompasses diverse types of activities, from basic science ("bench") to clinical medicine ("bedside") to bench-to-bedside translational research. It, however, remains unclear whether different types of research receive…

Digital Libraries · Computer Science 2019-12-17 Qing Ke

Drug discovery is lengthy and expensive, with traditional computer-aided design facing limits. This paper examines integrating quantum computing across the drug development cycle to accelerate and enhance workflows and rigorous…

In recent years, numerous machine learning models which attempt to solve polypharmacy side effect identification, drug-drug interaction prediction and combination therapy design tasks have been proposed. Here, we present a unified…

Machine Learning · Computer Science 2021-12-14 Benedek Rozemberczki , Stephen Bonner , Andriy Nikolov , Michael Ughetto , Sebastian Nilsson , Eliseo Papa

Drug repurposing has attracted increasing attention from both the pharmaceutical industry and the research community. Many existing computational drug repurposing methods rely on preclinical data (e.g., chemical structures, drug targets),…

Quantitative Methods · Quantitative Biology 2020-07-28 Qianlong Wen , Ruoqi Liu , Ping Zhang

A significant amount of high-impact contemporary scientific research occurs where biology, computer science, engineering and chemistry converge. Although programmes have been put in place to support such work, the complex dynamics of…

General Literature · Computer Science 2012-11-26 Naomi Jacobs , Martyn Amos

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Large Language Models (LLMs) have demonstrated their transformative potential across numerous disciplinary studies, reshaping the existing research methodologies and fostering interdisciplinary collaboration. However, a systematic…

Computation and Language · Computer Science 2025-07-14 Lu Xiang , Yang Zhao , Yaping Zhang , Chengqing Zong

Drug discovery is a complex process that involves sequentially screening and examining a vast array of molecules to identify those with the target properties. This process, also referred to as sequential experimentation, faces challenges…

Artificial Intelligence · Computer Science 2024-05-08 Jinghai He , Cheng Hua , Yingfei Wang , Zeyu Zheng

Keeping track of translational research is essential to evaluating the performance of programs on translational medicine. Despite several indicators in previous studies, a consensus measure is still needed to represent the translational…

Digital Libraries · Computer Science 2022-11-24 Xin Li , Xuli Tang , Wei Lu

The present paper takes its place in the stream of studies that analyze the effect of interdisciplinarity on the impact of research output. Unlike previous studies, in this study the interdisciplinarity of the publications is not inferred…

Digital Libraries · Computer Science 2018-10-31 Giovanni Abramo , Ciriaco Andrea D'Angelo , Flavia Di Costa

While "complexity science" has achieved significant successes in several interdisciplinary fields such as economics and biology, it is only a very recent observation that legal systems -- from the way legal texts are drafted and connected…

Physics and Society · Physics 2025-01-08 Pierpaolo Vivo , Daniel M. Katz , J. B. Ruhl