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Aim: In the present work, we aimed to evaluate a comprehensive radiomics framework that enabled prediction of EGFR and KRAS mutation status in NSCLC cancer patients based on PET and CT multi-modalities radiomic features and machine learning…

This paper proposes a deep learning-based denoising method for noisy low-dose computerized tomography (CT) images in the absence of paired training data. The proposed method uses a fidelity-embedded generative adversarial network (GAN) to…

Computer Vision and Pattern Recognition · Computer Science 2019-08-13 Hyoung Suk Park , Jineon Baek , Sun Kyoung You , Jae Kyu Choi , Jin Keun Seo

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted…

Due to privacy concerns, obtaining large datasets is challenging in medical image analysis, especially with 3D modalities like Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). Existing generative models, developed to address…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Jonghun Kim , Inye Na , Eun Sook Ko , Hyunjin Park

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo

Pathologies systematically induce morphological changes, thus providing a major but yet insufficiently quantified source of observables for diagnosis. The study develops a predictive model of the pathological states based on morphological…

Deep learning has been used extensively for medical image analysis applications, assuming the training and test data adhere to the same probability distributions. However, a common challenge arises when dealing with medical images generated…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Mohd Usama , Emma Nyman , Ulf Naslund , Christer Gronlund

While lung cancer is the second most diagnosed form of cancer in men and women, a sufficiently early diagnosis can be pivotal in patient survival rates. Imaging-based, or radiomics-driven, detection methods have been developed to aid…

Neural and Evolutionary Computing · Computer Science 2017-10-23 Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Early diagnosis of pathological invasiveness of pulmonary adenocarcinomas using computed tomography (CT) imaging would alter the course of treatment of adenocarcinomas and subsequently improve the prognosis. Most of the existing systems use…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Xiang Li , Jiechao Ma , Hongwei Li

In the context of brain tumor characterization, we focused on two key questions: (a) stability of radiomics features to variability in multiregional segmentation masks obtained with fully-automatic deep segmentation methods and (b)…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Maria Nadeem , Asma Shaheen , Muhammad F. A. Chaudhary , Hassan Mohy-ud-Din

Radiomics and deep learning both offer powerful tools for quantitative medical imaging, but most existing fusion approaches only leverage global radiomic features and overlook the complementary value of spatially resolved radiomic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Zengtian Deng , Yimeng He , Yu Shi , Lixia Wang , Touseef Ahmad Qureshi , Xiuzhen Huang , Debiao Li

Objectives: To develop and evaluate a radiomics machine learning model for detecting liver fibrosis on CT of the liver. Methods: For this retrospective, single-centre study, radiomic features were extracted from Regions of Interest (ROIs)…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Jay J. Yoo , Khashayar Namdar , Sean Carey , Sandra E. Fischer , Chris McIntosh , Farzad Khalvati , Patrik Rogalla

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…

This study leverages graph neural networks to integrate MELC data with Radiomic-extracted features for melanoma classification, focusing on cell-wise analysis. It assesses the effectiveness of gene expression profiles and Radiomic features,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Luis Carlos Rivera Monroy , Leonhard Rist , Martin Eberhardt , Christian Ostalecki , Andreas Bauer , Julio Vera , Katharina Breininger , Andreas Maier

Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on…

Computer Vision and Pattern Recognition · Computer Science 2015-11-12 Mohammad Javad Shafiee , Audrey G. Chung , Devinder Kumar , Farzad Khalvati , Masoom Haider , Alexander Wong

Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Removing the shape noise from the observed weak lensing field, i.e., denoising, enhances the potential of WL by accessing information at small scales where the shape noise dominates without denoising. We utilise two machine learning (ML)…

Cosmology and Nongalactic Astrophysics · Physics 2026-05-13 Shohei D. Aoyama , Ken Osato , Masato Shirasaki

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang