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This study introduces a new method of visualizing complex tree structured objects. The usefulness of this method is illustrated in the context of detecting unexpected features in a data set of very large trees. The major contribution is a…

Applications · Statistics 2012-02-14 Burcu Aydin , Gabor Pataki , Haonan Wang , Alim Ladha , Elizabeth Bullitt , J. S. Marron

Multimodal medical image fusion helps in combining contrasting features from two or more input imaging modalities to represent fused information in a single image. One of the pivotal clinical applications of medical image fusion is the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Nishant Kumar , Nico Hoffmann , Martin Oelschlägel , Edmund Koch , Matthias Kirsch , Stefan Gumhold

Joint modeling of multiview graphs with a common set of nodes between views and auxiliary predictors is an essential, yet less explored, area in statistical methodology. Traditional approaches often treat graphs in different views as…

Methodology · Statistics 2026-03-24 Sharmistha Guha , Jose Rodriguez-Acosta , Ivo Dinov

Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be…

Machine Learning · Computer Science 2020-05-26 Cooper J. Mellema , Alex Treacher , Kevin P. Nguyen , Albert Montillo

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Change point analysis has applications in a wide variety of fields. The general problem concerns the inference of a change in distribution for a set of time-ordered observations. Sequential detection is an online version in which new data…

Methodology · Statistics 2013-10-16 David S. Matteson , Nicholas A. James

In this paper, we review widely used statistical analysis frameworks for data defined along cortical and subcortical surfaces that have been developed in last two decades. The cerebral cortex has the topology of a 2D highly convoluted…

Neurons and Cognition · Quantitative Biology 2022-03-15 Moo K. Chung , Jamie L. Hanson , Seth D. Pollak

Finding the underlying relationships among multiple imaging modalities in a coherent fashion is one of challenging problems in the multimodal analysis. In this study, we propose a novel multimodal network approach based on multidi-…

Quantitative Methods · Quantitative Biology 2016-02-26 Hyekyoung Lee , Hyejin Kang , Moo K. Chung , Seonhee Lim , Bung-Nyun Kim , Dong Soo Lee

There is a widespread need for statistical methods that can analyze high-dimensional datasets with- out imposing restrictive or opaque modeling assumptions. This paper describes a domain-general data analysis method called CrossCat.…

Artificial Intelligence · Computer Science 2015-12-07 Vikash Mansinghka , Patrick Shafto , Eric Jonas , Cap Petschulat , Max Gasner , Joshua B. Tenenbaum

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

We study nonparametric methods for the setting where multiple distinct networks are observed on the same set of nodes. Such samples may arise in the form of replicated networks drawn from a common distribution, or in the form of…

Methodology · Statistics 2020-01-15 Swati Chandna , Pierre-Andre Maugis

-Background. Network neuroscience examines the brain as a complex system represented by a network (or connectome), providing deeper insights into the brain morphology and function, allowing the identification of atypical brain connectivity…

Neurons and Cognition · Quantitative Biology 2020-09-01 Mert Lostar , Islem Rekik

Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas.…

Neurons and Cognition · Quantitative Biology 2015-04-13 Tiago Simas , Mario Chavez , Pablo Rodriguez , Albert Diaz-Guilera

Structures of brain arterial networks (BANs) - that are complex arrangements of individual arteries, their branching patterns, and inter-connectivities - play an important role in characterizing and understanding brain physiology. One would…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Xiaoyang Guo , Aditi Basu Bal , Tom Needham , Anuj Srivastava

In clinical practice, medical segmentation datasets are often limited and heterogeneous, with variations in modalities, protocols, and anatomical targets across institutions. Existing deep learning models struggle to jointly learn from such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Weiwei Ma , Xiaobing Yu , Peijie Qiu , Jin Yang , Pan Xiao , Xiaoqi Zhao , Xiaofeng Liu , Tomo Miyazaki , Shinichiro Omachi , Yongsong Huang

Multi-view data, that is matched sets of measurements on the same subjects, have become increasingly common with advances in multi-omics technology. Often, it is of interest to find associations between the views that are related to the…

Machine Learning · Statistics 2020-10-02 Yunfeng Zhang , Irina Gaynanova

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Brain tissue segmentation from multimodal MRI is a key building block of many neuroscience analysis pipelines. It could also play an important role in many clinical imaging scenarios. Established tissue segmentation approaches have however…

Image and Video Processing · Electrical Eng. & Systems 2020-04-15 Reuben Dorent , Wenqi Li , Jinendra Ekanayake , Sebastien Ourselin , Tom Vercauteren